Synthesis of N-Acetylbenzimidazole Derivatives
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概要
- 論文の詳細を見る
For the structure determination of thiazolo [3,2-a] benzimidazol-3 (2H)-one derivatives (2 or 3) they were converted to the corresponding 1-acetylbenzimidazoles (4) by desulfurization. The latter compounds (4) were alternatively prepared by the cyclization of 2-aminoacetanilide derivatives (5) with CS_2 in dimethylformamide (DMF), followed by desulfurization with Raney Ni. However, the reactions of 5 with ethyl orthoformate/H_2SO_4 in DMF gave a mixture of 4 and its acetyl-rearranged product (7).
- 公益社団法人日本薬学会の論文
- 1982-08-25
著者
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田中 健二郎
School Of Pharmaceutical Science Toho University
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村上 泰興
School Of Pharmaceutical Science Toho University
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島崎 美知子
School of Pharmaceutical Science, Toho University
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島崎 美知子
School Of Pharmaceutical Science Toho University
関連論文
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- Fischer Indolization of Ethyl Pyruvate 2-[2-(Trifluoromethyl)phenyl]-phenylhydrazone and New Insight into the Mechanism of the Goldberg Reaction. (Fischer Indolization and Its Related Compounds. XXVI)
- A NEW SYNTHESIS OF EUPOLAURAMINE FROM A BENZ [f] INDOLE DERIVATIVE
- Synthetic Studies of Indoles and Related Compounds. XXVIII. Intramolecular Vinylation of Pyrrole Derivatives Using Palladium : a New Synthetic Method for Substituted Indoles
- A NEW GENERAL SYNTHETIC ROUTE FOR 1-SUBSITUTED 4-OXYGENATED β-CARBOLINES
- Synthetic Studies on Indoles and Related Compounds. XXVI. The Debenzylation of Protected Indole Nitrogen with Aluminum Chloride. (2)
- Fischer Indolization of Ethyl Pyruvate 2-Bis(2-methoxyphenyl)hydrazone and New Insight into the Mechanism of Fischer Indolization.(Fischer Indolization and Its Related Compounds. XXVII)
- Fischer Indolization and Its Related Compounds. XXIV. Fischer Indolization of Ethyl Pyruvate 2-(2-Methoxyphenyl)phenylhydrazone
- Fischer Indolization and Its Related Compounds. XXIII. Fischer Indolization of Ethyl Pyruvate 2-(2,6-Dimethoxyphenyl)phenylhydrazone
- New Synthetic Method for Dehydrotryptophan Derivatives. Synthetic Studies on Indoles and Related Compounds. XXXIV
- Synthetic Studies on Indoles and Related COmpounds. XXIX. Attempted Syntheses of Benz[f]indoles by Cyclization Reactions
- Abnormal Fischer Indolization and Its Related Compounds. XXII. : Fischer Indolization of Ethyl Pyruvate 2-(2-Chloro- and 2,6-Dichlorophynyl)methylhydrazones
- Reaction of Ethyl Acylindole-2-carboxylates with Thallium Trinitrate (Synthetic Studies on Indoles and Related Compounds. XXXIII)
- Synthetic Studies on Indoles and Related Compounds. XV. : An Unusual Acylation of Ethyl Indole-2-carboxylate in the Friedel-Crafts Acylation
- Synthetic Studies on Indoles and Related Compounds. XII. A Simple General Method for the C-3 Acylation of Ethyl Indole-2-carboxylates
- Determination of the Absolute Configuration of (-)-2-Bromosuccinamic Acid by X-Ray Diffraction Method
- An Efficient Synthesis of 1,1-Disubstituted Hydrazines
- Synthesis of N-Acetylbenzimidazole Derivatives
- Cyclization of [(4- or 5-Substituted-2-benzimidazolyl) thio] acetic Acids. Isolation and Identification of Two Possible Isomers of Substituted Thiazolo [3,2-a] benzimidazol-3 (2H)-one
- Fischer Indolization and Its Related Compounds. XVI. Vilsmeier-Haack Reaction of N-Methyl-1,2,3,4-tetrahydrocarbazole Derivatives
- Fischer Indolization and Its Related Compounds. XV. Vilsmeier-Haack Reaction of 1,2,3,4-Tetrahydrocarbazole Derivatives