Synthetic Studies on Indoles and Related Compounds. XII. A Simple General Method for the C-3 Acylation of Ethyl Indole-2-carboxylates

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概要

• 論文の詳細を見る

• Ethyl indole-2-carboxylate (1a) and its derivatives were reacted with various carboxylic acids by using trifluoroacetic anhydride and phosphoric acid (or polyphosphoric acid) to yield effectively the corresponding ethyl 3-acylindole-2-carboxylates (3). However, strongly acidic carboxylic acids and nitrogen-containing carboxylic acids were poor acylating agents. Ethyl 3-acylindole-2-carboxylate (3) could easily be converted to 3-acylindole (5)

• 公益社団法人日本薬学会の論文
• 1985-11-25

著者

• 谷 正宣

  School of Pharmaceutical Sciences, Toho University

• 横山 祐作

  School of Pharmaceutical Sciences, Toho University

• 村上 泰興

  School of Pharmaceutical Sciences, Toho University

• 田中 健二郎

  School Of Pharmaceutical Science Toho University

• 谷 正宣

  School Of Pharmaceutical Sciences Toho University

• 村上 泰興

  東邦大・薬

• 村上 泰興

  School Of Pharmaceutical Science Toho University

• 鈴木 通夫

  School of Pharmaceutical Science, Toho University

• 須藤 敬三

  School of Pharmaceutical Science, Toho University

• 上里 みどり

  School of Pharmaceutical Science, Toho University

• 鈴木 通夫

  School Of Pharmaceutical Science Toho University

• 須藤 敬三

  School Of Pharmaceutical Science Toho University

• 上里 みどり

  School Of Pharmaceutical Science Toho University

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