Anodic Oxidation of Amines. V. Cyclic Voltammetry and Controlled Potential Electrolysis of Ephedrine and the Related Compounds in Aqueous Buffer Solution
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概要
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The anodic oxidations of ephedrine and several realted compounds have been studied in aqueous buffer solutions at a glassy-carbon electrode. The oxidation potentials of these alkanol amines are less positive than those of simple alkyl amines without β-hydroxy group. On controlled potential electrolysis, these compounds consume about two electrons per molecule, and substantially give 1-hydroxy-1-phenyl-2-propanone and the counterpart alkylamines. The relative amount of dealkylation from the amino-nitrogen is quite different from that predicted on the basis of the number of α-protons.
- 公益社団法人日本薬学会の論文
- 1978-07-25
著者
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枡井 雅一郎
Faculty Of Pharmaceutical Sciences Osaka University
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尾崎 茂子
Faculty Of Pharmaceutical Sciences Osaka University
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