Psychotropic Agents. I. Synthesis of 1-Pyridinyl-1-butanones, 1-Indolyl-1-butanones and the Related Compounds
スポンサーリンク
概要
- 論文の詳細を見る
In order to search for new psychotropic agents, several 1-butanone derivatives (VIII) substituted by pyridine, indole or quinoline were synthesized. And the carbonyl group of VIII was modified to methylene (XII), secondary alcohol (XIII) and vinyl (XIV). The effects of the compounds on spontaneous motor activity and rotarod test in mice were determined. The structure-activity relationships of these derivatives are discussed.
- 社団法人日本薬学会の論文
- 1978-11-25
著者
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桜井 武男
Research Institute Daiichi Seiyaku Co. Ltd.
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佐藤 誠
Faculty of Pharmaceutical Sciences Toyama Medical and Pharmaceutical University
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小島 浩
Research Institute Daiichi Seiyaku Co. Ltd.
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佐藤 誠
Research Institute, Daiichi Seiyaku Co., Ltd.,
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田川 博昭
Research Institute, Daiichi Seiyaku Co., Ltd.
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小笹山 瑛
Research Institute, Daiichi Seiyaku Co., Ltd.
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内丸 文彦
Research Institute, Daiichi Seiyaku Co., Ltd.
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山崎 輝清
Research Institute, Daiichi Seiyaku Co., Ltd.
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小笹山 瑛
第一製薬
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田川 博昭
Exploratory Research Laboratories I Daiichi Pharmaceutical Co. Ltd.
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内丸 文彦
Research Institute Daiichi Seiyaku Co. Ltd.
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小笹山 瑛
Research Institute Daiichi Seiyaku Co. Ltd.
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山崎 輝清
Research Institute Daiichi Seiyaku Co. Ltd.
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