Modification of the Cysteamine Side Chain of Thienamycin. I
スポンサーリンク
概要
- 論文の詳細を見る
A new type of thienamycin derivative (2) having a monothioacetal side chain at the C-2 position was prepared by means of a replacement reaction of protected thienamycin sulfoxide (13) with the monothiohemiacetal (16) liberated in situ by the retro-Michael reaction of the masked thiol (12) with 1,8-diazabicyclo[5.4.0]undec-7-ene.
- 社団法人日本薬学会の論文
- 1986-03-25
著者
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藤原 弘之
Exploratory Research Laboratories Iii Daiichi Pharmaceutical Co. Ltd.
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東 邦雄
Drug Delivery System Institute Ltd.
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佐藤 誠
Faculty of Pharmaceutical Sciences Toyama Medical and Pharmaceutical University
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竹村 真
Research Institute, Daiichi Seiyaku Co., Ltd.,
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東 邦雄
Research Institute, Daiichi Seiyaku Co., Ltd.,
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藤原 弘之
Research Institute, Daiichi Seiyaku Co., Ltd.,
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佐藤 誠
Research Institute, Daiichi Seiyaku Co., Ltd.,
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古川 稔
Research Institute, Daiichi Seiyaku Co., Ltd.,
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古川 稔
Research Institute Daiichi Seiyaku Co. Ltd.
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竹村 真
Research Institute Daiichi Seiyaku Co. Ltd.
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