Direct Transformation of O-Glycoside into Glyosyl Bromide with the Combination of Trimethylsilyl Bromide and Zinc Bromide
スポンサーリンク
概要
- 論文の詳細を見る
A novel direct transformation of O-glycoside into glycosyl bromide by using trimethylsilyl bromide and zinc bromide has been developed. Treatment of various glycosides (3a-5a, 10,12 and 14) with trimethylsilyl bromide and zinc bromide in dichloromethane afforded the glycosyl bromides (6,11,13 and 15) in 53,85,94,47,41 and 40% yields, respectively.
- 社団法人日本薬学会の論文
- 1991-10-25
著者
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東 邦雄
Drug Delivery System Institute Ltd.
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日馬 恒雄
Exploratory Research Laboratories I Daiichi Pharmaceutical Co. Ltd.
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東 邦雄
Research Institute, Daiichi Seiyaku Co., Ltd.,
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中山 清
Exploratory Research Laboratories I, Daiichi Pharmaceutical Co. Ltd.,
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塩谷 恵美子
Exploratory Research Laboratories I, Daiichi Pharmaceutical Co., Ltd.,
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中山 清
Research Institute, Daiichi Pharmaceutical Co., Ltd.,
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塩谷 恵美子
Research Institute, Daiichi Pharmaceutical Co., Ltd.,
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日馬 恒雄
Research Institute, Daiichi Pharmaceutical Co., Ltd.,
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中山 清
Exploratory Research Laboratories I Daiichi Pharmaceutical Co. Ltd.
-
塩谷 恵美子
Exploratory Research Laboratories I Daiichi Pharmaceutical Co. Ltd.
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- Synthesis and Biological Activities of Lipid A Analogs : Modification of a Glycosidically Bound Group with Chemically Stable Polar Acidic Groups and Lipophilic Groups on the Disaccharide Backbone with Tetradecanoyl or N-Dodecanoylglycyl Groups
- Direct Transformation of O-Glycoside into Glyosyl Bromide with the Combination of Trimethylsilyl Bromide and Zinc Bromide
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