Lipase-Catalyzed Resolution of Sterically Crowded 1,2-Diols
スポンサーリンク
概要
- 論文の詳細を見る
An enzymatic method for preparation of the enantiomers of chiral diols 2a, b and their monoacetates 3a, b with 100% enantiomeric purity by using lipase-catalyzed esterification and/or hydrolysis was established, The (R)-enantiomers were more reactive in both acetylation of (±)-2a, b and hydrolysis of (±)-3a, b catalyzed by lipase OF-360 from Candida cylindracea.
- 社団法人日本薬学会の論文
- 1995-10-15
著者
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TANAKA Yasuko
Showa College of Pharmaceutical Sciences
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佐藤 誠
Research Institute, Daiichi Seiyaku Co., Ltd.,
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佐藤 誠
日本ヘキスト・マリオン・ルセル(株)研究開発本部開発研究所滋賀サイト
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Tanaka Y
Osaka University Of Pharmaceutical Science
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寺島 幸司
Research Laboratories, Roussel Morishita Co., Ltd.,
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田中 裕二
Research Laboratories, Roussel Morishita Co., Ltd.,
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KHLEBNIKOV Vladimir
Research Laboratories, Roussel Morishita Co., Ltd.,
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森 謙治
Department of Chemistry, Science University of Tokyo
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田中 裕二
Research Laboratories Roussel Morishita Co. Ltd.
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森 謙治
Department Of Chemistry Science University Of Tokyo
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Khlebnikov Vladimir
Research Laboratories Roussel Morishita Co. Ltd.
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寺島 幸司
Research Laboratories Roussel Morishita Co. Ltd.
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