Antitumor Agents. III. : A Novel Procedure for Inversion of the Configuration of a Tertiary Alcohol Related to Camptothecin
スポンサーリンク
概要
- 論文の詳細を見る
As part of our attempts to employ the unnatural (R)-type compound (8), which was produced by optical resolution of the pyranoindolizine 6,in the synthesis of natural (20S)-camptothecin, inversion of the configuration at the tertiary alcohol of the (4R)-pyranoindolizine 11 to give the (4S)-isomer 14 was achieved in 33% yield via the methanesulfonate 12.
- 公益社団法人日本薬学会の論文
- 1989-12-25
著者
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田川 博昭
Research Institute, Daiichi Seiyaku Co., Ltd.
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江島 明男
Exploratory Research Laboratories I, Daiichi Pharmaceutical Co., Ltd.
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寺沢 弘文
Exploratory Research Laboratories I, Daiichi Pharmaceutical Co., Ltd.
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杉森 正道
Exploratory Research Laboratories I, Daiichi Pharmaceutical Co., Ltd.
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江島 明男
Research Institute, Daiichi Seiyaku Co., Ltd.,
-
寺沢 弘文
Research Institute, Daiichi Seiyaku Co., Ltd.,
-
杉森 正道
Research Institute, Daiichi Seiyaku Co., Ltd.,
-
杉森 正道
Exploratory Research Laboratories I Daiichi Pharmaceutical Co. Ltd.
-
江島 明男
Exploratory Research Laboratories I Daiichi Pharmaceutical Co. Ltd.
-
田川 博昭
Exploratory Research Laboratories I Daiichi Pharmaceutical Co. Ltd.
-
寺沢 弘文
Exploratory Research Laboratories I Daiichi Pharmaceutical Co. Ltd.
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