Synthesis of Spiro [4-hydroxycyclohexane-1,4'-2', 3'-dihydro-6'-methoxy-2'-methyl-1'H-isoquinoline]
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概要
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For the purpose of testing the biological activity, spiro [4-hydroxycyclohexane-1,4'-2', 3'-dihydro-6'-methoxy-2'-methyl-1'H-isoquinoline] (III) was synthesized by a sequence of reactions including the Schmidt reaction on the indanone (XIV). The compound (III) was found to have a considerably lower anti-cholinesterase activity than galanthamine (I).
- 公益社団法人日本薬学会の論文
- 1969-08-25
著者
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八代 有
Faculty of Pharmaceutical Sciences Nagoya City University
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佐藤 隆司
Kyoto College Of Pharmacy
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佐藤 隆司
Faculty of Pharmacy, Meijo University
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白井 秀明
Faculty of Pharmaceutical Sciences, Nagoya City University
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