Decomposition of Usnic Acid. VI. Studies on the Ozonolytic Products of O, O-Diacetylusnic Acid.
スポンサーリンク
概要
- 論文の詳細を見る
The structure of the ethyl ester, C_<18>H_<22>O_<8>, m.p. 116°, which was obtained from O, O-diacetylusnic acid by the ozonolysis followed by alcoholysis was established by infrared spectral analyses as being ethyl 2-(2-hydroxy-3-acetyl-5-methyl-4,6-diacetoxy-phenyl)-propionate (VI). An alternative possible structure of usnic acid (IV) has therefore been excluded, and the structure of usnic acid (III) has been confirmed. The behaviors of lactone A, m.p. 132°, an ozonolytic product of O, O-diacetylusnic acid was reexamined. It was proved by infrared and nuclear magnetic resonance spectra, that reacetylation of deacetyl-lactone A with acetic anhydride and pyridine was affected at the 3-position of 2-coumaranone ring to furnish lactone B, m.p. 132°. Acetylating with acetic anhydride and conc. H_2SO_4,lactone A was regenerated from deacetyllactone A. Thus the earlier conclusions concerning with the lactones A and B have been corrected.
- 公益社団法人日本薬学会の論文
- 1962-06-25
著者
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庄司 順三
昭和大学薬学部
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柴田 承二
Meiji College of Pharmacy
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柴田 承二
Faculty of Pharmaceutical Sciences, University of Tokyo
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庄司 順三
Faculty of Pharmaceutical Sciences, Showa University
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柴田 承二
明治薬科大学
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清水 博
Faculty of Pharmaceutical Sciences, University of Tokyo
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江 雪郷
Faculty of Pharmaceutical Sciences, University of Tokyo
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Tokutake Norio
Faculty of Pharmaceutical Sciences, University of Tokyo
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Kaneko Yoshiyuki
Faculty of Pharmaceutical Sciences, University of Tokyo
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柴田 承二
Faculty Of Pharmaceutical Sciences University Of Tokyo
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Kaneko Yoshiyuki
Faculty Of Pharmaceutical Sciences University Of Tokyo
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Tokutake Norio
Faculty Of Pharmaceutical Sciences University Of Tokyo
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清水 博
Faculty Of Pharmaceutical Sciences University Of Tokyo
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江 雪郷
Faculty Of Pharmaceutical Sciences University Of Tokyo
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