Syntheses of 2-Hydroxymethylnicotinic Acid Lactone, 2-Hydroxymethylpyridine-3-acetic Acid Lactone, and Some of their Derivatives
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概要
- 論文の詳細を見る
New type 2,3-disubstituted pyridine lactones were prepared from 2-methylnicotinic acid. The lactones, 2-hydroxymethylnicotinic acid lactone and 2-hydroxymethylpyridine-3-acetic acid lactone, were reacted with various amines to form the corresponding lactams, and the lactams were reduced with lithium aluminium hydride, yielding pyrrolopyridine and 1,7-naphthyridine derivatives which possessed a fair degree of hypotensive action.
- 公益社団法人日本薬学会の論文
- 1960-05-25
著者
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宮寺 哲男
Takamine Forschungslaboratorium, Sankyo-AG.
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宮寺 哲男
Chemical Research Laboratories, Sankyo Co., Ltd.
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岩重 忠博
Takamine Research Laboratory, Sankyo Co. Ltd.
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岩重 忠博
三共中研
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岩重 忠博
Takamine Research Laboratory Sankyo Co. Ltd.
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宮寺 哲男
Chemical Research Laboratories Sankyo Co. Ltd.
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佐藤 義信
Takamine Research Laboratory Sankyo Co. Ltd.
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佐藤 義信
Takamine Research Laboratory, Sankyo Co., Ltd.
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