Isolation of Peridinin-Related Norcarotenoids with Cell Growth-Inhibitory Activity from the Cultured Dinoflagellate of Symbiodinium sp., a Symbiont of the Okinawan Soft Coral Clavularia viridis, and Analysis of Fatty Acids of the Dinoflagellate
スポンサーリンク
概要
- 論文の詳細を見る
Two norcarotenoids, 1 and 2, related to peridinin (3) were isolated from the cultured dinoflagellate of the genus Symbiodinium, a symbiont of the Okinawan soft coral Clavularia viridis, which contains in abundance anti-tumor marine prostanoids such as clavulones. The structures of 1 and 2 were elucidated on the basis of spectroscopic analysis. These compounds showed significant growth-inhibitory activity in vitro toward cancer cells. Analysis of fatty acids of the dinoflagellate was also carried out, suggesting that the marine prostanoids are produced by the host soft coral itself.
- 社団法人日本薬学会の論文
- 2003-06-01
著者
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WATANABE Kinzo
School of Life Sciences, Tokyo University of Pharmacy and Life Sciences
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IGUCHI Kazuo
School of Life Sciences, Tokyo University of Pharmacy and Life Sciences
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Iguchi K
東京薬科大学
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Watanabe K
School Of Life Science Tokyo University Of Pharmacy And Life Science
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Watanabe Kinzo
School Of Life Science Tokyo University Of Pharmacy And Life Science
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Yamori Takao
Cancer Chemotherapy Center Japanese Foundation For Cancer Research
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Yamori Takao
Cancer Chemotherapy Center Cancer Center
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Iguchi Kazuo
School Of Life Science Tokyo University Of Pharmacy And Life Science
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FUJIWARA Shoko
School of Life Science, Tokyo University of Pharmacy and Life Science
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WAKABAYASHI Takako
School of Life Science, Tokyo University of Pharmacy and Life Science
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TSUZUKI Mikio
School of Life Science, Tokyo University of Pharmacy and Life Science
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SUZUKI Motoya
School of Life Science, Tokyo University of Pharmacy and Life Science
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KURASAWA Toshie
School of Life Science, Tokyo University of Pharmacy and Life Science
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Tsuzuki Mikio
School Of Life Science Tokyo University Of Pharmacy And Life Science
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Fujiwara Shoko
School Of Life Science Tokyo University Of Pharmacy And Life Science
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Fujiwara S
School Of Life Science Tokyo University Of Pharmacy And Life Science
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Fujiwara Shoko
School Of Life Sciences Tokyo University Of Pharmacy And Life Sciences
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Fujiwara Shoko
Second Department Of Internal Medicine Osaka Medical College
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Fujiwara Shoko
Department Of Bacteriology Faculty Of Medicine Tottori University
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Suzuki Motoya
School Of Life Science Tokyo University Of Pharmacy And Life Science
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Wakabayashi T
School Of Life Science Tokyo University Of Pharmacy And Life Science
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Kurasawa Toshie
School Of Life Science Tokyo University Of Pharmacy And Life Science
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Wakabayashi Takako
School Of Life Science Tokyo University Of Pharmacy And Life Science
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Watanabe Kazuki
Faculty Of Pharmaceutical Sciences Aomori University
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Tsuzuki Mikio
School of Life Sciences, Tokyo University of Pharmacy and Life Sciences
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Yamori Takao
Cancer Chemotherapy Center
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