Isolation of Three Marine Prostanoids, Possible Biosynthetic Intermediates for Clavulones, from the Okinawan Soft Coral Clavularia viridis
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概要
- 論文の詳細を見る
Three marine prostanoids, 1, 2, and 3, were isolated from the extract of the Okinawan soft coral Clavularia viridis. The structures of these compounds were assigned based on the results of spectroscopic analysis. Compound 1 was shown to be preclavulone-A methyl ester, and this is the first isolation of the ester of preclavulone-A as a natural product. Preclavulone-A is proposed to be the key intermediate in the biosynthesis of marine prostanoids exemplified by clavulones in C. viridis. The new prostanoid 3 was suggested to be a biosynthetic intermediate from preclavulone-A to clavulones, and a possible biogenetic pathway via 3 is proposed.
- 公益社団法人日本薬学会の論文
- 2003-08-01
著者
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WATANABE Kinzo
School of Life Sciences, Tokyo University of Pharmacy and Life Sciences
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IGUCHI Kazuo
School of Life Sciences, Tokyo University of Pharmacy and Life Sciences
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Iguchi K
東京薬科大学
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Iguchi K
School Of Life Science Tokyo University Of Pharmacy And Life Science
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Watanabe Kinzo
School Of Life Science Tokyo University Of Pharmacy And Life Science
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Iguchi Kazuo
School Of Life Science Tokyo University Of Pharmacy And Life Science
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Sekine Miyuki
School of Life Science, Tokyo University of Pharmacy and Life Science
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Sekine Miyuki
School Of Life Science Tokyo University Of Pharmacy And Life Science
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