麹菌の変異に關する研究(第8報) : C 化學物質による誘發變異について(2)

概要

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We in vestigated various amino acids and organic acids that were ptoduced by the normal strains of Aspergillus oryzae and its variants which were obtained from the cultures on the madia containing merallic salts, in order to know whether any defference exists between the metabolic products of both these groups.1) Of the amino acids, cystine, aspartic acid and leucine were found in the matabolic products, especially cystine in a large amount. It is remarkable that the variants accumulate more cystine than the normal strains.2) In the absence of metallic complex salts, the normal strains were induced to vary by adding cystine in a concentration of 5 mg per 10 ml, but in their presence the strains needed cystine in a higher concentration ranging from 5 to 15 mg per 10 ml for variation.Any other amino acid in the above-mentioned concentrations could not induce the variation of the normal strains.
公益社団法人日本生物工学会の論文
1955-10-15