Experimental Head Injury & Concussion in Monkey Using Pure Linear Acceleration Impact
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概要
- 論文の詳細を見る
Translational acceleration head injury experiment was performed on 12 Japanese monkeys and one baboon using a HYGE sled and a slider-impactor system. All the monkeys became concussed by force ranging 241 to 366G in slider average acceleration and two of them died of concussion (fatal or irreversible concussion). The fatal concussion animals as well as the delayed death ones showed almost unexceptionally rib and clavicle fractures and mediastinal hemorrhage. Subarachnoid hemorrhage seen in six animals were not correlated with the outcome. We were unable to produce visible brain lesions, such as brain confusion, subdural hematoma, or intracerebral hematoma, by using pure translational acceleration impacts to the head. It should be misleading to draw a human or primate head injury tolerance limit from the fatal concussion level. Interestingly seven monkeys showed spontaneous eyelid blinking and four showed pupillary light reaction immediately post-impact and at least six animals showed "normal" EEG activity ten seconds after the impact. The cause of concussion was discussed and the role of cardiorespiratory supression by the primary shock is suggested.
- 社団法人日本脳神経外科学会の論文
著者
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Sano Keiji
Department Of Neurosurgery Faculty Of Medicine University Of Tokyo; Department Of Neurosurgery Tokyo
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Sano Keiji
Neurosurgery University Of Tokyo
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Sekino Hiroaki
Department Of Neurosurgery The Jikei University School Of Medicine
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Sekino Hiroaki
Department Of Neurosurgery University Of Tokyo
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NAKAMURA Norio
Department of Metabolic Engineering, Institute of Natural Medicine, Toyama Medical and Pharmaceutica
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HIRAKAWA Kimiyoshi
Department of Pulmonary Medicine, and University Medical School Teaching Hospital, Tokyo Medical and
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ABE Yuji
Department of Surgery, Kitakyushu Municipal Medical Center
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Hirakawa Kimiyoshi
Department Of Neurosurgery University Of Tokyo
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Hirakawa Kimiyoshi
Department Of Neurosurgery Faculty Of Medicine University Of Tokyo; Department Of Neurosurgery Tokyo
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Mii Koji
Department of Neurosurgery,University of Tokyo
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Masuzawa Hideaki
Department of Neurosurgery,University of Tokyo
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MATSUNO Masanori
Department of Neurosurgery, Faculty of Medicine, University of Tokyo; Department of Neurosurgery, To
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Hirakawa Kimiyoshi
University of Tokyo
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Matsuno Masanori
Department Of Neurosurgery Faculty Of Medicine University Of Tokyo; Department Of Neurosurgery Tokyo
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Mii Koji
Department Of Neurosurgery University Of Tokyo Faculty Of Medicine
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Mii Koji
Department Of Emergency Medicine Faculty Of Medicine University Of Tokyo
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Mii Koji
Department Of Neurosurgery University Of Tokyo
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Hirakawa Kimiyoshi
Deparmtent Of Neurosurgery:faculty Of Medicine University Of Tokyo
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Masuzawa Hideaki
Department Of Neurosurgery University Of Tokyo Faculty Of Medicine
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Masuzawa Hideaki
Department Of Neurosurgery Kanto Teishin Hospital
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Masuzawa Hideaki
Dept. Of Neurosurgery University Of Tokyo
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Shimizu Hiroyuki
Department Of Neurosurgery Faculty Of Medicine University Of Tokyo
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Sekino Hiroaki
Department Of Neurological Surgery Central Hospital Of Japanese National Rialways
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Sekino Hiroaki
Department Of Neurosurgery Tokyo Police Hospital:bokuto Hospital
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Nakamura Norio
Department Of Neurosurgery The Jikei University School Of Medicine
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Abe Yuji
Department Of Obstetrics And Gynecology Toho University School Of Medicine
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Nakamura Norio
Neurosurgery Faculty Of Medicine University Of Tokyo
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Sekino Hiroaki
Dept. Of Neurosurgery University Of Tokyo
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Sano Keiji
Department Of Hepato-biliary-pancreatic Surgery Japanese Red Cross Medical Center
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Abe Yuji
Department Of Chest Surgery Kitakyushu Municipal Medical Center
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Abe Yuji
Department Of Neurosurgery Faculty Of Medicine University Of Tokyo; Department Of Neurosurgery Tokyo
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Sano Keiji
Department Of Neurosurgery Faculty Of Medicine University Of Tokyo; Department Of Neurosurgery Tokyo
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Nakamura Norio
Department Of Biology Yokohama City University
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Abe Yuji
Department Of Biofunctional Research National Institutefor Longeviiy Sciences
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Nakamura Norio
Department Of Anatomy Gunma University School Of Medicine
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Masuzawa Hideaki
Neurosurgery Faculty Of Medicine University Of Tokyo
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Sano Keiji
Department Neurosurgery University Of Tokyo
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Masuzawa Hideaki
Neurosurgical Service Toritsu Fuchu General Hospital:department Of Neurosurgery Faculty Of Medicine
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Sano Keiji
Deparmtent Of Neurosurgery:faculty Of Medicine University Of Tokyo
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Shimizu Hiroyuki
Department Of Neurosurgery Tokyo Police Hospital:bokuto Hospital
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Hirakawa Kimiyoshi
Department Of Neurosurgery Faculty Of Medicine University Of Tokyo; Department Of Neurosurgery Tokyo
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