Growth Inhibition of Human Glioma Cells by Superinduced Human Interferon-β
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概要
- 論文の詳細を見る
ヒトグリオーマ細胞から超誘発法によって得られたヒトインターフェロンβは高い細胞障害活性を持っている。しかし超誘発法に用いられる試剤の細胞障害活性を排除するためにその用量を最小限度に抑えてachnomycinDは除外した。超誘発法における試剤の組み合せにおいて全ての増殖抑制効果はヒトインターフェロンβモノクローナル抗体(YSB-1)によって完全に中和され、試剤自身には細胞増殖抑制効果がないことを証明した。また超誘発法からカラムクロマトグラフィーによって精製された内因性のインターフェロンβは同種と異種のグリオーマ細胞株に対して細胞増殖抑制効果を示し、オートクリンとパラクリンの効果を持つと思われた。
- 日本脳神経外科学会の論文
- 1995-10-15
著者
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Yoshida Jun
Department Of Neurosurgery Nagoya University Graduate School Of Medicine
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NARUSE NORIO
Basic Research Laboratories, Toray Industries, Inc.
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Wakabayashi Toshihiko
Department of Neurosurgery, Nagoya University Graduate School of Medicine
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SUGITA Kenichiro
Department of Neurosurgery,Nagoya University School of Medicine
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Nagata Masaaki
厚生連加茂病院脳神経外科
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Wakabayashi Toshihiko
Department Of Neurosurgery Nagoya University Graduate School Of Medicine
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Sugita Kenichiro
Department Of Neurosurgery Nagoya University School Of Medicine
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UTSUMI Jun
Basic Research Laboratories, Toray Industries, Inc.
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Utsumi Jun
Basic Research Laboratories Toray Industries Inc.
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Naruse Norio
Basic Research Laboratories Toray Industries Inc.
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根橋 京子
Department of Neurosurgery, Nagoya University School of Medicine
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根橋 京子
Department Of Neurosurgery Nagoya University School Of Medicine:(present Address)department Of Neuro
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Wakabayashi Toshihiko
Department Of Neurosurgery Graduate School Of Medicine Nagoya University
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Yoshida Jun
Department Of Basic Science Graduate School Of Arts And Sciences The University Of Tokyo
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