STUDY OF EXAMINATION METHODS FOR ASSESSING MALE FERTILITY DISTURBANCES 2.THE SPERM EVALUATION USING ADRIAMYCIN
スポンサーリンク
概要
- 論文の詳細を見る
- 日本トキシコロジー学会の論文
- 1994-11-30
著者
-
Kawashima Kunio
Division of Toxicology, National Institute of Health Sciences
-
SAKEMI Kazue
Division of Pharmacology, National Institute of Health Sciences
-
TAKANAKA Akira
Division of Pharmacology, BSRC, National Institute of Hygienic Sciences
-
Ueda Makoto
Division Of Pathology National Institute Of Health Sciences
-
Sakemi Kazue
Division Of Pharmacology National Institute Of Health Sciences
-
Usami Makoto
Division of Pharmacology, National Institute of Health Sciences
-
Kitaura K
Univ. Tokushima School Of Medicine Tokushima
-
KAWASHIMA Kunio
National Institute of Health Sciences
-
Takahashi Atsushi
Division Of Pharmacology National Institute Of Hygienic Sciences
-
Sakemi K
Division Of Pharmacology National Institute Of Health Sciences
-
Sakemi Kazue
Division Of Pharmacology And Biological Safety Research Center National Institute Of Health Sciences
-
Sakemi Kazue
Division Of Pharmacology National Institute Of Hygienic Sciences
-
Kitaura Keisuke
Department Of Pathology National Institute Of Health Sciences
-
TAKANAKA Akira
The Organization for Pharmaceutical Safety and Research
-
Usami Makoto
Division Of Pharmacology Biological Safety Research Center National Institute Of Health Sciences
-
Takanaka Akira
Division Of Pharmacology Bsrc National Institute Of Hygienic Sciences
-
Takanaka A
National Inst. Hygienic Sciences Tokyo Jpn
-
Kawashima Kunio
Division Of Pharmacology National Institute Of Hygienic Sciences
-
Kawashima Kunio
Division Of Pharmacology Biological Safety Research Center National Institute Of Health Sciences
-
Usami M
Division Of Pathology National Institute Of Health Sciences
-
Sakemi Kazue
国立医薬品食品衛生研究所
-
Takahashi A
Division Of Pharmacology Bsrc National Institute Of Hygienic Sciences
-
Usami Makoto
Division Of Pathology National Institute Of Health Sciences
-
Kawashima Kunio
Division Of Biological Evaluation National Institute Of Health Science Osaka Branch
-
Kawashima Kunio
Department Of Pathology National Institute Of Health Sciences
-
Usami Makoto
Division of Nutrition and Metabolism, Department of Biophysics, Kobe University Graduate School of Health Sciences
関連論文
- Comparison of enhancing effects of different goitrogen treatments in combination with β-estradiol-3-benzoate for establishing a rat two-stage thyroid carcinogenesis model to detect modifying effects of estrogenic compounds
- Lack of Modifying Effect of Glycerol in Pulmonary Carcinogenesis in rasH2 Mice Induced by Urethane or 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)
- Modulatory effects of hepatic, renal or thyroidal impairments on amitrole-induced thyroid carcinogenesis in rats pretreated with DHPN (CARCINOGENICITY) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
- Inhibiting Effects of Ethinylestradiol on N-ethyl-M-nitrosourea-Initiated Uterine Carcinogenesis in Transgenic Mice Carrying a Human Prototype C-Ha-ras Gene (rasH2 mice) (CARCINOGENICITY) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th A
- Safety evaluetion of Bt protein by dietary administration to a gastro-intestinal impairment rat model (GENERAL TOXICITY) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
- Promoting Effects of Ethinylestradiol but not Atrazine on N-ethyl-N-nitrosourea-induced Uterine Carcinogenesis in ICR Mice
- Difference in the Types of Uterine Tumors between Heterozygous p53-deficient and Wild Type CBA Mice Treated with Ethinylestradiol after N-ethyl-N-nitrosourea Initiation
- Modifying effect of atrazine on DMBA-induced mammary carcinogenesis in ovariectomized rats.(GENERAL SESSION BY POSTER PRESENTATION)(CARCINOGENICITY)
- Modifying Effects of Genistein, 4-Nonylphenol and Methoxychlor on N-ethyl-N-nitrosourea-induced Uterine Carcinogenesis in RasH2 Transgenic Mice Harboring a Human Prototype C-Ha-ras Gene
- Enhancing Effects β-Estradiol 3-Benzoate but Not Methoxychlor on the Promotion/Progression Stage of Chemically-induced Mammary Carcinogenesis in Ovariectomized Rats
- GONADAL TOXICITY OF AN ETHANOL EXTRACT OF PSORALEA CORYLIFOLIA IN A RAT 90-DAY REPEATED DOSE STUDY
- Prevention by 2-Mercaptoethane Sulfonate and N-Acetylcysteine of Renal Oxidative Damage in Rats Treated with Ferric Nitrilotriacetate
- "C-1 Reproductive and Developmental Toxicity Studies of Toluene. : II. Effects of inhalation exposure on fertility in rats.
- 21C-03-4 Effects of 2-Mercaptobenzimidazole (MBI) and its methyl derivatives MMBI on rat hepatic drug metabolizing enzymes.
- "B-11 Effects of triazine herbicides on isolated and primary cultured hepatocytes of rat.
- THE EFFECT OF DIQUAT ON THE GAP JUNCTIONAL INTERCELLULAR COMMUNICATION BETWEEN RAT HEPATOCYTES IN PRIMARY CULTURE
- EFFECTS OF ORGANIC PHOSPHOROUS COMPOUNDS AND THEIR METABOLITES ON RAT HEPATOCYTES IN THE PRIMARY CULTURE
- Development of invasive follicular cell carcinomas in a rat thyroid carcinogenesis model : Biological impact of capsular inflammation and reduced cyclooxygenase-2 expression
- Induction of Squamous Cell Carcinomas in the Salivary Glands of Rats by Potassium Iodide
- Possible enhancing effects of atrazine on growth of 7, 12-dimethylbenz(a) anthracene-induced mammary tumors in ovariectomized Sprague-Dawley rats
- P1-IS-1 Transcriptional expression of survivin and its splice variants in cervical carcinomas
- P-IS-43 Vascular endothelial growth factor-C expression and invasive phenotype in ovarian carcinomas(Oncology 11,Group 98,International Session)
- P-IS-28 Germline polymorphism of p53 codon 72 in gynecological cancer(Oncology 7,Group 94,International Session)
- P-IS-19 Transcriptional expression of the genes implicated in angiogenesis and tumorinvasion in cervical carcinomas(Oncology 5,Group 92,International Session)
- P-IS-15 Fas gene promoter-670 polymorphism in cervical carcinogenesis(Oncology 4,Group 91,International Session)
- P-IS-10 Therapeutic potential of neoadjuvant intraarteial chemotherapy in patients with locally advanced cervical adenocarcinoma(Oncology 3,Group 90,International Session)
- Homeobox gene expression and mutation in cervical carcinoma cells
- Homeobox gene expression and mutation in cervical carcinoma cells(Session5 Oncology5)
- Biological implications of survivin gene expression in the development of endometriosis and endometrial carcinoma(Session3 Oncology3)
- Regulation of Dihydropyrimidine Dehydrogenase and Pyrimidine Nucleoside Phosphorylase Activities by Growth Factors and Subsequent Effects on 5-Fluorouracil Sensitivity in Tumor Cells
- Effects of Sex Steroids and Growth Factors on Invasive Activity and 5'-Deoxy-5-fluorouridine Sensitivity in Ovarian Adenocarcinoma OMC-3 Cells
- Sexing of postimplantation rat embryos in stored two-dimensional electrophoresis (2-DE) samples by polymerase chain reaction (PCR) of an Sry sequence
- 22D-10-5 Effect of WY-14643 on Hepatocyte Proliferation in Male Rats.
- Changes of plasma lipid metabolism in hypothyroid rats
- Effects of various drugs on biliary excretion of thyroid hormones in rats
- Collaborative work on evaluation of ovarian toxicity : 7) Effects of 2- or 4-week repeated dose studies and fertility study of cyclophosphamide in female rats
- Lack of Role of Platelet Aggregation on 2-Bromoethylamine Hydrobromide-induced Renal Papillary Necrosis in Rats
- P-94 Collaboratie Work to Evaluate Toxicity on Male Reproductive Organs by Repeated Dose Studies in Rats. : 15)Effects of a Single Oral Dose of Cyclophosphamide.(Proceedings of the 27th Annual Meeting)
- COLLABORATIVE WORK TO EVALUATE TOXICITY ON MALE REPRODUCTIVE ORGANS BY REPEATED DOSE STUDIES IN RATS : 13)EFFECTS OF A SINGLE ORAL DOSE OF CYCLOPHOSPHAMIDE
- 22A-10-2 Application of Zona-Free Hamster Egg Sperm Penetration Tests for Testing Fertility of Male Rats Treated with Adriamycin
- MECHANISTIC STUDY ON INHIBITION OF SERUM THYROID HORMONE PRODUCTION BY THIOUREA
- THYROID PROLIFERATIVE LESIONS INDUCED BY ANTI-THYROID DRUGS IN RATS ARE NOT ALWAYS ACCOMPANIED BY SUSTAINED INCREASES IN SERUM TSH
- Low Susceptibility of Long-Evans Cinnamon Rats to N-Butyl-N-(4-hydroxybutyl)-nitrosamine-induced Urinary Bladder Carcinogenesis and Inhibitory Effect of Urinary Copper
- Effects of D-Galactosamine Hydrochloride and Partial Hepatectomy on Spontaneous Hepatic Injury and Hepatocarcinogenesis in Long-Evans Cinnamon Rats
- Role of Copper Accumulation in Spontaneous Renal Carcinogenesis in Long-Evans Cinnamon Rats
- Effects of tacrolimus (FK506) on induction of glutathione S-transferase P-positive foci and liver cell regeneration after partial hepatectomy in F344 rats
- P-103 Collaborative Work to Evaluate Toxicity on Male Reproductive Organs by A 2-Week Repeated-Dose Toxicity Study in Rats : 29)Summary.(Proceedings of the 27th Annual Meeting)
- COLLABORATIVE WORK TO EVALUATE TOXICITY ON MALE REPRODUCTIVE ORGANS BY REPEATED DOSE STUDIES IN RATS : OVERVIEW OF THE STUDIES
- EFFECT OF PHOSPHORIC ACID TRI-ESTERS FLAME RETARDANTS ON THE PRENATAL AND POSTNATAL DEVELOPMENTS OF THE RATS
- STUDY ON THE SPERM MOTILITY, COUNT OR MORPHOLOGICAL CHANGE AND MALE FERTILITY DISTURBANCE INDUCED BY CHEMICALS
- TOXICITY STUDY OF A RUBBER ANTIOXIDANT, 2-MERCAPTOBENZIMIDAZOLE, BY REPEATED ORAL ADMINISTRATION TO RATS
- A 13-WEEK TOXICITY STUDY OF SIMULTANEOUS ADMINISTRATION OF COCHINEAL AND ALUMINUM POTASSIUM SULFATE IN RATS
- 416 ACUTE AND SUBCHRONIC TOXICITY STUDIES OF 2, 2'-METHYLENEBIS (4-METHYL-6-TERT-BUTYLPHENOL) (MBMBP) IN RATS
- A20 STUDY ON THE DEPRESSED BODY WEIGHT GAIN INDUCED BY 2, 2'-METHYLENE-bis(4-ETHYL-6-tert-BUTYLPHENOL)(MBEBP) IN RAT
- ACUTE, SUBCHRONIC AND CHRONIC TOXICITY STUDIES OF A SYNTHETIC ANTIOXIDANT, 2,2'-METHYLENEBIS(4-METHYL-6-TERT-BUTYLPHENOL) IN RATS
- CHRONIC ORAL TOXICITY STUDY OF A SYNTHETIC ANTIOXIDANT, 2, 2'-METHYLENEBIS(4-ETHYL-6-TERT-BUTYLPHENOL)(MBEBP)IN RATS
- B38 COMPARISON OF TOXICITY OF p-DCB IN MALE AND FEMALE RATS
- The Rab GTPase-Activating Protein AS160 as a Common Regulator of Insulin- and Gαq-Mediated Intracellular GLUT4 Vesicle Distribution
- Effect of Estradiol and Nonyiphenol on mRNA Expression of Estrogen Receptors α and β, and Cytochrome P450 Aromatase in the Gonad of Chicken Embryos
- Suppressive Effect of p-Nonylphenol on Male-Specific mRNA Expression in the Embryonic Gonad of Chickens
- Effect of Estradiol and Nonylphenol on mRNA Levels of VitellogeninII in the Liver of Chicken Embryos
- O11-12 Modifying effects of endocrine disrupting chemicals on ENU-induced uterine carcinogenesis in heterozygous p53 deficient CBA mice.
- 231 ANALYSIS OF THE NATIONAL TOXICOLOGY PROGRAM DATA ON IN VITRO GENETIC TOXICITY TESTS, OCTANOL/WATER PARTITION COEFFICIENTS AND ACUTE TOXICITY USING MULTIVARIATE STATISTICAL METHOD
- "P-35 Contribution of Oxidative Stress to Rat Hepatotoxicity induced by 2-Nitropropane : Lipid Peroxidation and Inhibitory Effect of Green Tea.
- CONFIRMATION STUDY, USING NITROBENZENE, OF THE COMBINED REPEAT DOSE AND REPRODUCTIVE/DEVELOPMENTAL TOXICITY TEST PROTOCOL PROPOSED BY THE ORGANIZATION FOR ECONOMIC COOPERATION AND DEVELOPMENT (OECD)
- COMMUTATIVITY OF OPERATORS
- A-1 MECHANISM UNDERLING NEUROTOXICITY OF CHLORDECONE : AN ELECTROPHYSIOLOGICAL APPROACH USING PC12 PHEOCHROMOCYTOMA CELLS
- Sperm test using CASA (HTM-IVOS) 1. α-chlorohydrin.
- EFFECTS ON FETAL GROWTH OF REPEATED BLOOD COLLECTION FOR TOXICOKINETICS FROM PREGNANT RATS
- STUDY OF EXAMINATION METHODS FOR ASSESSING MALE FERTILITY DISTURBANCES 1.QUANTITATIVE MORPHOMETRICAL EVALUATION OF TESTICULAR TOXICITY OF ADRIAMYCIN
- "B-3 Toxicokinetic Study of 2-Mercaptobenzimidazole (MBI) and its Methylated Derivative (MMBI) in Rats after Single Oral-Dose Administration.
- ORIGIN AND CHARACTERISTICS OF FRESHLY ISOLATED RENAL CELLS OBTAINED BY PERFUSION OF COLLAGENASE IN VITRO
- COMPARISONS OF THE TOXICOKINETIC PARAMETERS IN RATS DETERMINED FOR LOW AND HIGH DOSE OF γ-CHLORDANE
- COMPARATIVE STUDY ON METABOLISM OF N-NITROSODIMETHYLAMINE AND N-NITROSOMETHYLBENZYLAMINE IN RAT LIVER
- RENAL MICROSOMAL N-NITROSODIMETHYLAMINE DEMETHYLASE DETERMINED BY A SENSITIVE RADIOMETRIC METHOD
- COMPARATIVE TOXICOKINETIC STUDY OF RUBBER ANTIOXIDANTS, 2-MERCAPTOBENZIMIDAZOLE AND 2-MERCAPTOMETHYLBENZIMIDAZOLE, BY SINGLE ORAL ADMINISTRATION IN RATS
- 22D-11-3 Increased Liver and Kidney Toxicities in Rats Caused by Co-administration of 2-Mercaptobenzimidazole (MBI) and Lipopolysaccharide (LPS) and Their Toxicokinetics (TK).
- Comparison of Thyroid Toxicity and Toxicokinetics of 2-Mercapto-4-methylbenzimidazole (4MeMBI) and its 5-Methyl Isomer (5MeMBI), Rubber antioxidant, in Rats by Single and Repeated Oral-Dose Administrations
- Endogenous Nitric Oxide Formation Stimulated by LPS in Hypothyroid Rats Induced by 2-Mercaptobenzimidazole (MBI)
- 2C-13 Toxicokinetic Study of 2-Mercapto-benzimidazole(MBI) and its Methylated Derivative (MMBI) in Rats Treated by Repeated Oral Administration - Metabolism and urinary Excretion
- 2C-12 Toxicokinetic Study of 2-Mercapto-benzimidazole(MBI) and its Methylated Derivative (MMBI) in Rats Treated by Repeated Oral Administration.
- In Vivo Effect of Nucleotide and Nucleosides (OG-VI) Solution and Dietary Nucleotide Deficiency on Tumor Proliferation With Coadministration of 5-Fluorouracil (5 FU)
- Developmental toxicity of indium : Embryotoxicity and teratogenicity in experimental animals
- 219 EFFECTS OF 2-MONOCHLORODIBENZOFURAN AND 3-MONOCHLORODIBENZOFURAN ON THE P450-MEDIATED DRUG METABOLIZING ENZYME ACTIVITIES OF PRIMARY CULTURED RAT HEPATOCYTES : COMPARISION WITH THE EFFECTS OF DIOXINS AND METHLCHOLANTHRENE
- STUDIES ON THE ESTABLISHMENT OF APPROPRIATE SPERMATOGENIC ENDPOINTS FOR MALE FERTILITY DISTURBANCE IN RODENT INDUCED BY DRUGS AND CHEMICALS I. NITROBENZENE
- STUDY OF EXAMINATION METHODS FOR ASSESSING MALE FERTILITY DISTURBANCES 2.THE SPERM EVALUATION USING ADRIAMYCIN
- EFFECTS OF DEPLETION OF EMBRYONIC GLUTATHIONE ON SELENIUM TERATOGENICITY IN CULTURED RAT EMBRYOS
- EFFECTS OF VARIOUS INDUCERS ON THE ACTIVITIES OF CYTOCHROME P-450-MIXED FUNCTION OXIDASES AND AFLATOXIN B_1 ACTIVATION IN MICROSOMES OF HAMSTER LIVERS
- IN VITRO NEUROTOXICITY ASSAY SYSTEM BY NEURONAL CLONES (1) : EFFECTS OF CHLORDANE ON ELECTROPHYSIOLOGICAL PROPERTIES OF HYBRID NEURONAL CLONE NG 108-15
- A-15 IN VITRO TERATOGENICITY TESTING USING THE RAT EMBRYO CULTURE SYSTEM : (3) EFFECTS OF CYCLOPHOSPHAMIDE ON RAT EMBRYONIC DEVELOPMENT IN VITRO AND IN VIVO
- A-6 EFFECT OF BIS (TRIBUTYLTIN) PHTHALATE ON THE FETAL DEVELOPMENT
- C12 IN VITRO TERATOGENICITY TESTING USING THE RAT EMBRYO CULTURE SYSTEM : (1) EFEECTS OF SODIUM SALICYLATE ON RAT EMBRYONIC DEVELOPMENT IN VITRO AND IN VIVO
- C03 SYNERGIC EFFECT OF MESTRANOL ON VIRILIZING ACTIVITY OF NORETHYNODREL IN FEMALE RAT FETUSES
- EFFECT OF INTRAMUSCULAR INJECTION OF DRUGS ON SERUM CPK ACTIVITY IN RABBITS
- TERATOLOGICAL STUDIES OF ZINC ETHYLPHENYLDITHIOCARBAMATE (ZEPC), A VULCANIZATION ACCELERATOR FOR RUBBERS, IN RATS
- "A-13 p-Phenylenediamines, antioxidative ingredients for rubber compound : a quantitative evaluation of their skin sensitization in guinea pig (GPMT)
- The Relationship of IL-6 to Hormonal Mediators,Fuel Utilization,and Systemic Hypermetabolism after Surgical Trauma
- 218 EFFECTS OF 2- AND 3-CHLORODIBENZOFURANS ON THE DEVELOPMENT OF CULTURED POSTIMPLANTATION RAT EMBRYOS
- Toxic effects of a horseradish extract and allyl isothiocyanate in the urinary bladder after 13-week administration in drinking water to F344 rats
- Lack of Modifying Effects of Bisphenol A and Roasted-Ground Soybean (Kinako) on N-ethyl-N-nitrosourea-Induced Uterine Carcinogenesis in Heterozygous p53 Deficient CBA Mice