THE EFFECT OF DIQUAT ON THE GAP JUNCTIONAL INTERCELLULAR COMMUNICATION BETWEEN RAT HEPATOCYTES IN PRIMARY CULTURE
スポンサーリンク
概要
- 論文の詳細を見る
- 日本トキシコロジー学会の論文
- 1994-11-30
著者
-
OHNO Yasuo
Division of Pharmacology, National Institute of Health Science
-
Ohe Yuichiro
国立医薬品食品衛生研究所
-
Ohe Yuichiro
Department Of Medical Oncology National Cancer Center Hospital
-
MIYAJIMA Atsuko
Project Team for Pharmacogenetics, National Institute of Health Sciences
-
MIYAJIMA Atsuko
Division of Pharmacology, National Institute of Health Sciences
-
Miyajima Atsuko
Project Team For Pharmacogenetics National Institute Of Health Sciences
-
SUNOUCHI Momoko
Division of Pharmacology, National Institute of Health Sciences
-
SUNOUCHI Momoko
Div. Pharmacol., Natl. Inst. Health Sci.
-
MIYAJIMA Atsuko
Div. Pharmacol., Natl. Inst. Health Sci.
-
ZHANG Baoxu
Natl. Inst. Health Sci.
-
Zhang Baoxu
Division of pharmacology, National Institute of Health Sciences
-
TAKANAKA Akira
Division of Pharmacology, BSRC, National Institute of Hygienic Sciences
-
Miyajima A
Project Team For Pharmacogenetics National Institute Of Health Sciences
-
Miyajima Atsuko
Division Of Pharmacology Biological Safety Research Center National Institute Of Health Sciences
-
Ohno Yasuo
Div. Of Pharmacology Biological Safty Research Center National Institute Of Hygienic Sciences
-
Takahashi Atsushi
Division Of Pharmacology National Institute Of Hygienic Sciences
-
Miyajima Atsuko
Div. Pharmacol. Natl. Inst. Health Sci.
-
TAKANAKA Akira
The Organization for Pharmaceutical Safety and Research
-
Takanaka Akira
Division Of Pharmacology Bsrc National Institute Of Hygienic Sciences
-
Takanaka A
National Inst. Hygienic Sciences Tokyo Jpn
-
Sunouchi Momoko
Div. Pharmacol. Natl. Inst. Health Sci.
-
Sunouchi Momoko
Div. Of Pharmacology National Institute Of Hygienic Sciences
-
Sunouchi Momoko
Division Of Pharmacol. Mutagen. Nihs
-
Ohno Yasuo
Division Of Internal Medicine And Thoracic Oncology National Cancer Center Hospital
-
Takahashi A
Division Of Pharmacology Bsrc National Institute Of Hygienic Sciences
関連論文
- Genetic Variations and Haplotypes of ABCC2 Encoding MRP2 in a Japanese Population
- 日本人におけるGSTT1及びGSTM1の遺伝子多型の同定及びハプロタイプ構造の解析
- Genetic Variations of VDR/NR1I1 Encoding Vitamin D Receptor in a Japanese Population
- Genetic Variations and Frequencies of Major Haplotypes in SLCO1B1 Encoding the Transporter OATP1B1 in Japanese Subjects : SLCO1B1^*17 is More Prevalent Than ^*15
- Expression of CYP2A6 in Tumor Cells Augments Cellular Sensitivity to Tegafur
- Three novel single nucleotide polymorphisms in UGT1A10
- Sequence-based Analysis of the CYP2D6^*36-CYP2D6^*10 Tandem-type Arrangement, a Major CYP2D6^*10 Haplotype in the Japanese Population
- Novel Nonsynonymous Single Nucleotide Polymorphisms in the CYP2D6 Gene
- 21C-03-4 Effects of 2-Mercaptobenzimidazole (MBI) and its methyl derivatives MMBI on rat hepatic drug metabolizing enzymes.
- 21C-03-3 Effects of Diphenyl on Hepatic Peroxysomal Enzyme and Drug-Metabolizing Enzyme Activities in BDF1 Mice.
- Sulfating-Activity and Stability of cDNA-Expressed Allozymes of Human Phenol Sulfotransferase, ST1A31 (^Arg) and ST1A32 (^His), Both of Which Exist in Japanese as Well as Caucasians^1
- 2C-17 Effects of Substituted Phenylurea Pesticides and Their Metabolites in Freshly Isolated and Cultured Rat Hepatocytes.
- "B-11 Effects of triazine herbicides on isolated and primary cultured hepatocytes of rat.
- EFFECT OF CARBAMATES ON RAT HEPATOCYTES IN THE PRIMARY CULTURE
- EFFECT OF CARBAMATES ON RAT FRESHLY ISOLATED HEPATOCYTES
- THE EFFECT OF DIQUAT ON THE GAP JUNCTIONAL INTERCELLULAR COMMUNICATION BETWEEN RAT HEPATOCYTES IN PRIMARY CULTURE
- EFFECT OF ORGANOPHOSPHORUS COMPOUNDS AND THEIR METABOLITES ON RAT FRESHLY ISOLATED HEPATOCYTES
- EFFECTS OF ORGANIC PHOSPHOROUS COMPOUNDS AND THEIR METABOLITES ON RAT HEPATOCYTES IN THE PRIMARY CULTURE
- Interferon-γ-inducing Factor Gene Transfection into Lewis Lung Carcinoma Cells Reduces Tumorigenicity in vivo
- Epidermal growth factor receptor mutation status and clinicopathological features of combined small cell carcinoma with adenocarcinoma of the lung
- Functional and physical interaction between Sgs1 and Top3 and Sgs1-independent function of Top3 in DNA recombination repair
- Different domains of Sgs1 are required for mitotic and meiotic functions
- Characterization of the Properties of a Human Homologue of Escherichia coli RecQ from Xeroderma Pigmentosum Group C and from HeLa Cells
- Gene Expression Property of High-Density Three-Dimensional Tissue of HepG2 Cells Formed in Radial-Flow Bioreactor(BIOINFORMATICS)
- Three-Dimensional High-Density Culture of HepG2 Cells in a 5-ml Radial-Flow Bioreactor for Construction of Artificial Liver(Biochemical Engineering)
- 日本人で新たに見いだされた低活性型CYP2D6ハプロタイプ
- The Novel Compounds That Activate Farnesoid X Receptor : the Diversity of Their Effects on Gene Expression
- Sexing of postimplantation rat embryos in stored two-dimensional electrophoresis (2-DE) samples by polymerase chain reaction (PCR) of an Sry sequence
- CYP3A4 Gene Polymorphisms Influence Testosterone 6β-hydroxylation
- P-103 Collaborative Work to Evaluate Toxicity on Male Reproductive Organs by A 2-Week Repeated-Dose Toxicity Study in Rats : 29)Summary.(Proceedings of the 27th Annual Meeting)
- COLLABORATIVE WORK TO EVALUATE TOXICITY ON MALE REPRODUCTIVE ORGANS BY REPEATED DOSE STUDIES IN RATS : OVERVIEW OF THE STUDIES
- EFFECT OF PHOSPHORIC ACID TRI-ESTERS FLAME RETARDANTS ON THE PRENATAL AND POSTNATAL DEVELOPMENTS OF THE RATS
- Ethnic Differences in Genetic Polymorphisms of CYP2D6, CYP2C19, CYP3As and MDR1/ABCB1
- Expression vector with DNA of bovine papilloma virus 1 for keratinocyte gene therapy
- STUDY ON THE SPERM MOTILITY, COUNT OR MORPHOLOGICAL CHANGE AND MALE FERTILITY DISTURBANCE INDUCED BY CHEMICALS
- Bodyweight change during the first 5 days of chemotherapy as an indicator of cisplatin renal toxicity
- Problems with Registration-Directed Clinical Trials for Lung Cancer in Japan
- Phase I study of cisplatin, vinorelbine, and concurrent thoracic radiotherapy for unresectable stage III non-small cell lung cancer
- Tumor response to chemotherapy : The validity and reproducibility of RECIST guidelines in NSCLC patients
- Prospective Evaluation of the Feasibility of Cisplatin-based Chemotherapy for Elderly Lung Cancer Patients with Normal Organ Functions
- Interindividual Variability in 5-Fluorouracil Metabolism and Procainamide N-Acetylation in Human Liver Cytosol(Biochemistry/Molecular Biology)
- Interindividual Variability in 2-Hydroxylation, 3-Sulfation, and 3-Glucuronidation of Ethynylestradiol in Human Liver(Biochemistry/Molecular Biology)
- 21C-01-3 Genetic polymorphisms of carcinogen-activating human phenol sulfotransferase and arylamine n-acetyltransferase, and urothelial cancer susceptibiltiy.
- STUDY ON THE TOXICITY OF 2,2'-METHYLENE-bis(4-ETHYL-6-tert-BUTYLPHENOL) IN RAT (NO.1)
- "C-5 Validation of alternatives to eye irritation tests for cosmetic ingredients (Results of the first, second, and third validation).
- Effect of Estradiol and Nonyiphenol on mRNA Expression of Estrogen Receptors α and β, and Cytochrome P450 Aromatase in the Gonad of Chicken Embryos
- Suppressive Effect of p-Nonylphenol on Male-Specific mRNA Expression in the Embryonic Gonad of Chickens
- Effect of Estradiol and Nonylphenol on mRNA Levels of VitellogeninII in the Liver of Chicken Embryos
- Improvement in Reliability of Probabilistic Test of Significant Differences in GeneChip Experiments
- TOXICITY STUDIES OF A SYNTHETIC ANTIOXIDANT, 2,2'-METHYLENEBIS (4-ETHYL-6-TERT-BUTYLPHENOL) IN RATS 2. UNCOUPLING EFFECT ON OXIDATIVE PHOSPHORYLATION OF LIVER MITOCHONDRIA
- Long-term follow-up of patients with unresectable locally advanced non-small cell lung cancer treated with chemoradiotherapy: A retrospective analysis of the data from the Japan Clinical Oncology Group trials (JCOG0003A)
- Chemoradiotherapy for lung cancer : current status and perspectives
- A-1 MECHANISM UNDERLING NEUROTOXICITY OF CHLORDECONE : AN ELECTROPHYSIOLOGICAL APPROACH USING PC12 PHEOCHROMOCYTOMA CELLS
- STUDIES ON NITROSAMINE FORMATION BY THE INTERACTION BETWEEN DRUGS AND NITRITE. I. : Measurement of the amount of nitrosamine formed in rat and guinea pig stomachs.
- EFFECTS ON FETAL GROWTH OF REPEATED BLOOD COLLECTION FOR TOXICOKINETICS FROM PREGNANT RATS
- Genetic Polymorphisms of Copper- and Platinum Drug-efflux Transporters ATP7A and ATP7B in Japanese Cancer Patients
- STUDY OF EXAMINATION METHODS FOR ASSESSING MALE FERTILITY DISTURBANCES 1.QUANTITATIVE MORPHOMETRICAL EVALUATION OF TESTICULAR TOXICITY OF ADRIAMYCIN
- O-35 Benefits of surgical materials in drug development(Proceedings of the 27th Annual Meeting)
- "B-3 Toxicokinetic Study of 2-Mercaptobenzimidazole (MBI) and its Methylated Derivative (MMBI) in Rats after Single Oral-Dose Administration.
- Phase I study of TLR9 agonist PF-3512676 in combination with carboplatin and paclitaxel in patients with advanced non-small-cell lung cancer
- "B-2 Metabolic Study of Tris(2-Chloroethyl) Phosphate (TCEP) in vivo and in vitro.
- LOSS OF VIABILITY AFTER DISULFIRAM TREATMENT WITHOUT PRECEDING DEPLETION OF INTRACELLULAR GSH
- ORIGIN AND CHARACTERISTICS OF FRESHLY ISOLATED RENAL CELLS OBTAINED BY PERFUSION OF COLLAGENASE IN VITRO
- MORPHINE METABOLISM IN ISOLATED HEPATOCYTES AND ITS IMPLICATIONS FOR HEPATOTOXICITY
- COMPARISONS OF THE TOXICOKINETIC PARAMETERS IN RATS DETERMINED FOR LOW AND HIGH DOSE OF γ-CHLORDANE
- FETAL TOXICITY OF ZINC ETHYLPHENYLDITHIOCARBAMATE(ZEPC)(3). MECHANISM OF FORMATION OF METHEMOGLOBIN CAUSED BY ZEPC
- COMPARATIVE STUDY ON METABOLISM OF N-NITROSODIMETHYLAMINE AND N-NITROSOMETHYLBENZYLAMINE IN RAT LIVER
- RENAL MICROSOMAL N-NITROSODIMETHYLAMINE DEMETHYLASE DETERMINED BY A SENSITIVE RADIOMETRIC METHOD
- INFLUENCE OF DOSE ON THE TOXICOKINETICS OF γ-CHLORDANE
- STUDIES ON NITROSAMINE FORMATION BY THE INTERACTION BETWEEN DRUGS AND NITRITE. II. : Hepatotoxicity by the simultaneous administration of several drugs and nitrite.
- COMPARATIVE TOXICOKINETIC STUDY OF RUBBER ANTIOXIDANTS, 2-MERCAPTOBENZIMIDAZOLE AND 2-MERCAPTOMETHYLBENZIMIDAZOLE, BY SINGLE ORAL ADMINISTRATION IN RATS
- 22D-11-3 Increased Liver and Kidney Toxicities in Rats Caused by Co-administration of 2-Mercaptobenzimidazole (MBI) and Lipopolysaccharide (LPS) and Their Toxicokinetics (TK).
- Comparison of Thyroid Toxicity and Toxicokinetics of 2-Mercapto-4-methylbenzimidazole (4MeMBI) and its 5-Methyl Isomer (5MeMBI), Rubber antioxidant, in Rats by Single and Repeated Oral-Dose Administrations
- Endogenous Nitric Oxide Formation Stimulated by LPS in Hypothyroid Rats Induced by 2-Mercaptobenzimidazole (MBI)
- 2C-13 Toxicokinetic Study of 2-Mercapto-benzimidazole(MBI) and its Methylated Derivative (MMBI) in Rats Treated by Repeated Oral Administration - Metabolism and urinary Excretion
- 2C-12 Toxicokinetic Study of 2-Mercapto-benzimidazole(MBI) and its Methylated Derivative (MMBI) in Rats Treated by Repeated Oral Administration.
- 219 EFFECTS OF 2-MONOCHLORODIBENZOFURAN AND 3-MONOCHLORODIBENZOFURAN ON THE P450-MEDIATED DRUG METABOLIZING ENZYME ACTIVITIES OF PRIMARY CULTURED RAT HEPATOCYTES : COMPARISION WITH THE EFFECTS OF DIOXINS AND METHLCHOLANTHRENE
- 215 MUTAGENIC ACTIVATION OF 2- AND 3-CHLORODIBENZOFURANS BY LIVER MICROSOMES AND THE CORRELATION WITH CYTOCHROME P-450 ISOZYMES
- A04 EFFECTS OF METYRAPONE ON THE CYTOCHROME P450 MEDIATED DRUG METABOLIZING ACTIVITIES IN THE PRIMARY CULTURES OF RAT HEPATOCYTES
- STUDIES ON THE ESTABLISHMENT OF APPROPRIATE SPERMATOGENIC ENDPOINTS FOR MALE FERTILITY DISTURBANCE IN RODENT INDUCED BY DRUGS AND CHEMICALS I. NITROBENZENE
- STUDY OF EXAMINATION METHODS FOR ASSESSING MALE FERTILITY DISTURBANCES 2.THE SPERM EVALUATION USING ADRIAMYCIN
- A Pharmacokinetic and Pharmacodynamic Analysis of CPT-11 and Its Active Metabolite SN-38
- EFFECTS OF VARIOUS INDUCERS ON THE ACTIVITIES OF CYTOCHROME P-450-MIXED FUNCTION OXIDASES AND AFLATOXIN B_1 ACTIVATION IN MICROSOMES OF HAMSTER LIVERS
- Preservative solution for freeze-storage of surgically excised human colon to enable study of smooth muscle function in vitro
- Report 2 : THE POSSIBILITY OF PREDICTING TISSUE ACCUMULATION AFTER REPEATED DOSING USING A SINGLE-DOSE TISSUE DISTRIBUTION STUDY (Repeated dose tissue distribution studies)
- Report 1 : OUTLINE AND DISCUSSION POINTS OF GUIDANCE FOR REPEATED DOSE TISSUE DISTRIBUTION STUDIES (Repeated dose tissue distribution studies)
- EFFECTS OF TRIS (2, 3-DIBROMOPROPYL) PHOSPHATE ON THE PRENATAL AND POSTNATAL DEVELOPMENTS OF THE RATS (The 6th Meeting for the Study of Toxic Effect)
- STUDIES ON THE TERATOGENICITY OF FURYLFURAMIDE IN FETUSES AND OFFSPRING OF RATS IN RELATION TO FETAL DISTRIBUTION
- IN VITRO NEUROTOXICITY ASSAY SYSTEM BY NEURONAL CLONES (1) : EFFECTS OF CHLORDANE ON ELECTROPHYSIOLOGICAL PROPERTIES OF HYBRID NEURONAL CLONE NG 108-15
- Studies on an Establishment of Cells Expressing Human Vasopressin Receptpr and Its Characterlzation.
- A-15 IN VITRO TERATOGENICITY TESTING USING THE RAT EMBRYO CULTURE SYSTEM : (3) EFFECTS OF CYCLOPHOSPHAMIDE ON RAT EMBRYONIC DEVELOPMENT IN VITRO AND IN VIVO
- A-6 EFFECT OF BIS (TRIBUTYLTIN) PHTHALATE ON THE FETAL DEVELOPMENT
- Toxicity Evaluation by using primary cultured rat hepatocytes
- W4-3 Toxicity Evaluation by using primary cultured rat hepatocytes
- C12 IN VITRO TERATOGENICITY TESTING USING THE RAT EMBRYO CULTURE SYSTEM : (1) EFEECTS OF SODIUM SALICYLATE ON RAT EMBRYONIC DEVELOPMENT IN VITRO AND IN VIVO
- C03 SYNERGIC EFFECT OF MESTRANOL ON VIRILIZING ACTIVITY OF NORETHYNODREL IN FEMALE RAT FETUSES
- EFFECT OF INTRAMUSCULAR INJECTION OF DRUGS ON SERUM CPK ACTIVITY IN RABBITS
- TERATOLOGICAL STUDIES OF ZINC ETHYLPHENYLDITHIOCARBAMATE (ZEPC), A VULCANIZATION ACCELERATOR FOR RUBBERS, IN RATS
- A new device for the determination of microsomal cytochrome P-450 in renal tissue preparations from various species contaminated with mitochondria and hemoglobin.
- Sulfating-Activity and Stability of cDNA-Expressed Allozymes of Human Phenol Sulfotransferase, ST1A3*1 (213Arg) and ST1A3*2 (213His), Both of Which Exist in Japanese as Well as Caucasians.