TERATOLOGICAL STUDIES OF ZINC ETHYLPHENYLDITHIOCARBAMATE (ZEPC), A VULCANIZATION ACCELERATOR FOR RUBBERS, IN RATS
スポンサーリンク
概要
- 論文の詳細を見る
- 日本トキシコロジー学会の論文
- 1983-11-25
著者
-
Kawashima Kunio
Division of Toxicology, National Institute of Health Sciences
-
Tanaka Satoru
Division of Toxicology, National Institute of Health Sciences
-
TAKANAKA Akira
Division of Pharmacology, BSRC, National Institute of Hygienic Sciences
-
TANAKA Satoru
Toxicology Laboratory, Kissei Pharmaceutical Co., Ltd.
-
Ohno Yasuo
Div. Of Pharmacology Biological Safty Research Center National Institute Of Hygienic Sciences
-
Kitaura K
Univ. Tokushima School Of Medicine Tokushima
-
Kitaura Keisuke
Second Department Of Pathology The University Of Tokushima School Of Medicine
-
Takahashi Atsushi
Division Of Pharmacology National Institute Of Hygienic Sciences
-
NAKAURA Shinsuke
Division of Pharmacology, Biological Safty Research Centet, National Institute of Hygienic Sciences
-
OMORI Yoshihito
Division of Pharmacology, Biological Safty Research Centet, National Institute of Hygienic Sciences
-
Tanaka Satoru
Division Of Pharmacology National Institute Of Hygienic Sciences
-
TAKANAKA Akira
The Organization for Pharmaceutical Safety and Research
-
Takanaka Akira
Division Of Pharmacology Bsrc National Institute Of Hygienic Sciences
-
Takanaka A
National Inst. Hygienic Sciences Tokyo Jpn
-
Kawashima Kunio
Division Of Pharmacology National Institute Of Hygienic Sciences
-
Kawashima Kunio
Division Of Pharmacology Biological Safety Research Center National Institute Of Health Sciences
-
Omori Yoshihito
Division Of Pharmacology Biological Safety Research Center National Institute Of Hygienic Sciences:d
-
Nakaura Shinsuke
Biosafety Research Center Food Drugs And Pesticides
-
Tanaka Satoru
Division Of Internal Medicine Shizuoka City Hospital
-
Takahashi A
Division Of Pharmacology Bsrc National Institute Of Hygienic Sciences
-
Kawashima Kunio
Division Of Biological Evaluation National Institute Of Health Science Osaka Branch
-
Tanaka Satoru
Division Of Internal Medicine And Thoracic Surgery Shizuoka City Hospital
-
Kawashima Kunio
Department Of Pathology National Institute Of Health Sciences
-
Takayama Satoshi
Research Department Saitama Daiichi Pharmaceutical Co. Ltd. Japanese Pharmaceutical Manufacturers Association
関連論文
- Genetic Variations and Haplotypes of ABCC2 Encoding MRP2 in a Japanese Population
- 日本人におけるGSTT1及びGSTM1の遺伝子多型の同定及びハプロタイプ構造の解析
- Genetic Variations of VDR/NR1I1 Encoding Vitamin D Receptor in a Japanese Population
- Genetic Variations and Frequencies of Major Haplotypes in SLCO1B1 Encoding the Transporter OATP1B1 in Japanese Subjects : SLCO1B1^*17 is More Prevalent Than ^*15
- Expression of CYP2A6 in Tumor Cells Augments Cellular Sensitivity to Tegafur
- Three novel single nucleotide polymorphisms in UGT1A10
- Sequence-based Analysis of the CYP2D6^*36-CYP2D6^*10 Tandem-type Arrangement, a Major CYP2D6^*10 Haplotype in the Japanese Population
- Salbutamol inhibits lipopolysaccharide-induced inflammatory responses in rat peritoneal macrophages
- "C-1 Reproductive and Developmental Toxicity Studies of Toluene. : II. Effects of inhalation exposure on fertility in rats.
- Reproductive and Developmental Toxicity Studies of Toluene.I.Teratogenicity Study of Inhalation Exposure in Pregnant Rats.
- REPRODUCTIVE AND DEVELOPMENTAL TOXICITY STUDIES OF TOLUENE I. TERATOGENICITY STUDY OF INHALATION EXPOSURE IN PREGNANT RATS
- 21C-03-4 Effects of 2-Mercaptobenzimidazole (MBI) and its methyl derivatives MMBI on rat hepatic drug metabolizing enzymes.
- 21C-03-3 Effects of Diphenyl on Hepatic Peroxysomal Enzyme and Drug-Metabolizing Enzyme Activities in BDF1 Mice.
- Sulfating-Activity and Stability of cDNA-Expressed Allozymes of Human Phenol Sulfotransferase, ST1A31 (^Arg) and ST1A32 (^His), Both of Which Exist in Japanese as Well as Caucasians^1
- 2C-17 Effects of Substituted Phenylurea Pesticides and Their Metabolites in Freshly Isolated and Cultured Rat Hepatocytes.
- "B-11 Effects of triazine herbicides on isolated and primary cultured hepatocytes of rat.
- EFFECT OF CARBAMATES ON RAT HEPATOCYTES IN THE PRIMARY CULTURE
- EFFECT OF CARBAMATES ON RAT FRESHLY ISOLATED HEPATOCYTES
- THE EFFECT OF DIQUAT ON THE GAP JUNCTIONAL INTERCELLULAR COMMUNICATION BETWEEN RAT HEPATOCYTES IN PRIMARY CULTURE
- EFFECT OF ORGANOPHOSPHORUS COMPOUNDS AND THEIR METABOLITES ON RAT FRESHLY ISOLATED HEPATOCYTES
- EFFECTS OF ORGANIC PHOSPHOROUS COMPOUNDS AND THEIR METABOLITES ON RAT HEPATOCYTES IN THE PRIMARY CULTURE
- Salbutamol inhibits lipopolysaccharide-induced inflammatory responses in rat peritoneal macrophages
- Induction of Squamous Cell Carcinomas in the Salivary Glands of Rats by Potassium Iodide
- -3-CORONARY ARTERIAL SPASM AS A CAUSE OF EXERTIONAL ANGINA PECTORIS : Ischemic Heart Disease : PROCEEDINGS OF THE 42nd ANNUAL MEETING OF THE JAPANESE CIRCULATION SOCIETY
- RESPONSE OF ANGINA AT REST TO VARIOUS DRUGS : Vth Auditorium : PROCEEDINGS OF THE 40TH ANNUAL MEETING OF THE JAPANESE CIRCULATION SOCIETY
- Gene Expression Property of High-Density Three-Dimensional Tissue of HepG2 Cells Formed in Radial-Flow Bioreactor(BIOINFORMATICS)
- Three-Dimensional High-Density Culture of HepG2 Cells in a 5-ml Radial-Flow Bioreactor for Construction of Artificial Liver(Biochemical Engineering)
- P1-IS-1 Transcriptional expression of survivin and its splice variants in cervical carcinomas
- 日本人で新たに見いだされた低活性型CYP2D6ハプロタイプ
- CYP3A4 Gene Polymorphisms Influence Testosterone 6β-hydroxylation
- 22A-10-2 Application of Zona-Free Hamster Egg Sperm Penetration Tests for Testing Fertility of Male Rats Treated with Adriamycin
- P-103 Collaborative Work to Evaluate Toxicity on Male Reproductive Organs by A 2-Week Repeated-Dose Toxicity Study in Rats : 29)Summary.(Proceedings of the 27th Annual Meeting)
- COLLABORATIVE WORK TO EVALUATE TOXICITY ON MALE REPRODUCTIVE ORGANS BY REPEATED DOSE STUDIES IN RATS : OVERVIEW OF THE STUDIES
- EFFECT OF PHOSPHORIC ACID TRI-ESTERS FLAME RETARDANTS ON THE PRENATAL AND POSTNATAL DEVELOPMENTS OF THE RATS
- Ethnic Differences in Genetic Polymorphisms of CYP2D6, CYP2C19, CYP3As and MDR1/ABCB1
- PRINZMETAL'S VARIANT FORM OF ANGINA AND ALPHA ADRENERGIC RECEPTOR MEDIATED CORONARY ARTERIAL SPASM
- THE ROLE OF AUTONOMIC NERVOUS SYSTEM IN THE PATHOGENESIS OF PRINZMETAL'S VARIANT FORM OF ANGINA : PROCEEDINGS OF THE 38TH ANNUAL MEETING OF THE JAPANESE CIRCULATION SOCIETY
- STUDY ON THE SPERM MOTILITY, COUNT OR MORPHOLOGICAL CHANGE AND MALE FERTILITY DISTURBANCE INDUCED BY CHEMICALS
- Bodyweight change during the first 5 days of chemotherapy as an indicator of cisplatin renal toxicity
- 2A-13 Reproductive and Developmental Toxicity Studies of Toluene. III. Prenatal and postnatal study by inhalation exposure in rats.
- Problems with Registration-Directed Clinical Trials for Lung Cancer in Japan
- Phase I study of cisplatin, vinorelbine, and concurrent thoracic radiotherapy for unresectable stage III non-small cell lung cancer
- Tumor response to chemotherapy : The validity and reproducibility of RECIST guidelines in NSCLC patients
- Prospective Evaluation of the Feasibility of Cisplatin-based Chemotherapy for Elderly Lung Cancer Patients with Normal Organ Functions
- 21C-01-3 Genetic polymorphisms of carcinogen-activating human phenol sulfotransferase and arylamine n-acetyltransferase, and urothelial cancer susceptibiltiy.
- STUDY ON THE TOXICITY OF 2,2'-METHYLENE-bis(4-ETHYL-6-tert-BUTYLPHENOL) IN RAT (NO.1)
- TISSUE- AND DOSE-DEPENDENT ALTERATION OF STRESS-INDUCIBLE PROTEINS BY β_2-ADRENOCEPTOR AGONIST, SALBUTAMOL, IN RATS
- QUANTITATIVE ESTIMATION OF MYOCARDIAL FIBROSIS BASED ON RECEPTOR OCCUPANCY FOR β_2-ADRENERGIC RECEPTOR AGONISTS IN RATS
- Improvement in Reliability of Probabilistic Test of Significant Differences in GeneChip Experiments
- CONFIRMATION STUDY, USING NITROBENZENE, OF THE COMBINED REPEAT DOSE AND REPRODUCTIVE/DEVELOPMENTAL TOXICITY TEST PROTOCOL PROPOSED BY THE ORGANIZATION FOR ECONOMIC COOPERATION AND DEVELOPMENT (OECD)
- Strain differences in phenobarbital metabolism between SD and Wistar rats(Proceedings of the 32nd Annual Meeting)
- TOXICITY STUDIES OF A SYNTHETIC ANTIOXIDANT, 2,2'-METHYLENEBIS (4-ETHYL-6-TERT-BUTYLPHENOL) IN RATS 2. UNCOUPLING EFFECT ON OXIDATIVE PHOSPHORYLATION OF LIVER MITOCHONDRIA
- Long-term follow-up of patients with unresectable locally advanced non-small cell lung cancer treated with chemoradiotherapy: A retrospective analysis of the data from the Japan Clinical Oncology Group trials (JCOG0003A)
- A-1 MECHANISM UNDERLING NEUROTOXICITY OF CHLORDECONE : AN ELECTROPHYSIOLOGICAL APPROACH USING PC12 PHEOCHROMOCYTOMA CELLS
- STUDIES ON NITROSAMINE FORMATION BY THE INTERACTION BETWEEN DRUGS AND NITRITE. I. : Measurement of the amount of nitrosamine formed in rat and guinea pig stomachs.
- Sperm test using CASA (HTM-IVOS) 1. α-chlorohydrin.
- Strain differences in hepatic cytochrome P450 1A and 3A expression between Sprague-Dawley and Wistar rats
- EFFECTS ON FETAL GROWTH OF REPEATED BLOOD COLLECTION FOR TOXICOKINETICS FROM PREGNANT RATS
- Genetic Polymorphisms of Copper- and Platinum Drug-efflux Transporters ATP7A and ATP7B in Japanese Cancer Patients
- STUDY OF EXAMINATION METHODS FOR ASSESSING MALE FERTILITY DISTURBANCES 1.QUANTITATIVE MORPHOMETRICAL EVALUATION OF TESTICULAR TOXICITY OF ADRIAMYCIN
- O-35 Benefits of surgical materials in drug development(Proceedings of the 27th Annual Meeting)
- "B-3 Toxicokinetic Study of 2-Mercaptobenzimidazole (MBI) and its Methylated Derivative (MMBI) in Rats after Single Oral-Dose Administration.
- Phase I study of TLR9 agonist PF-3512676 in combination with carboplatin and paclitaxel in patients with advanced non-small-cell lung cancer
- LOSS OF VIABILITY AFTER DISULFIRAM TREATMENT WITHOUT PRECEDING DEPLETION OF INTRACELLULAR GSH
- ORIGIN AND CHARACTERISTICS OF FRESHLY ISOLATED RENAL CELLS OBTAINED BY PERFUSION OF COLLAGENASE IN VITRO
- MORPHINE METABOLISM IN ISOLATED HEPATOCYTES AND ITS IMPLICATIONS FOR HEPATOTOXICITY
- COMPARISONS OF THE TOXICOKINETIC PARAMETERS IN RATS DETERMINED FOR LOW AND HIGH DOSE OF γ-CHLORDANE
- FETAL TOXICITY OF ZINC ETHYLPHENYLDITHIOCARBAMATE(ZEPC)(3). MECHANISM OF FORMATION OF METHEMOGLOBIN CAUSED BY ZEPC
- COMPARATIVE STUDY ON METABOLISM OF N-NITROSODIMETHYLAMINE AND N-NITROSOMETHYLBENZYLAMINE IN RAT LIVER
- RENAL MICROSOMAL N-NITROSODIMETHYLAMINE DEMETHYLASE DETERMINED BY A SENSITIVE RADIOMETRIC METHOD
- INFLUENCE OF DOSE ON THE TOXICOKINETICS OF γ-CHLORDANE
- STUDIES ON NITROSAMINE FORMATION BY THE INTERACTION BETWEEN DRUGS AND NITRITE. II. : Hepatotoxicity by the simultaneous administration of several drugs and nitrite.
- COMPARATIVE TOXICOKINETIC STUDY OF RUBBER ANTIOXIDANTS, 2-MERCAPTOBENZIMIDAZOLE AND 2-MERCAPTOMETHYLBENZIMIDAZOLE, BY SINGLE ORAL ADMINISTRATION IN RATS
- 22D-11-3 Increased Liver and Kidney Toxicities in Rats Caused by Co-administration of 2-Mercaptobenzimidazole (MBI) and Lipopolysaccharide (LPS) and Their Toxicokinetics (TK).
- Comparison of Thyroid Toxicity and Toxicokinetics of 2-Mercapto-4-methylbenzimidazole (4MeMBI) and its 5-Methyl Isomer (5MeMBI), Rubber antioxidant, in Rats by Single and Repeated Oral-Dose Administrations
- Endogenous Nitric Oxide Formation Stimulated by LPS in Hypothyroid Rats Induced by 2-Mercaptobenzimidazole (MBI)
- 2C-13 Toxicokinetic Study of 2-Mercapto-benzimidazole(MBI) and its Methylated Derivative (MMBI) in Rats Treated by Repeated Oral Administration - Metabolism and urinary Excretion
- 2C-12 Toxicokinetic Study of 2-Mercapto-benzimidazole(MBI) and its Methylated Derivative (MMBI) in Rats Treated by Repeated Oral Administration.
- STUDIES ON THE OPTIMAL TREATMENT PERIOD AND PARAMETERS FOR DETECTION OF MALE FERTILITY DISORDER IN RATS : INTRODUCTORY SUMMARY (<SPECIAL ISSUE>TESTICULAR TOXICITY)
- 219 EFFECTS OF 2-MONOCHLORODIBENZOFURAN AND 3-MONOCHLORODIBENZOFURAN ON THE P450-MEDIATED DRUG METABOLIZING ENZYME ACTIVITIES OF PRIMARY CULTURED RAT HEPATOCYTES : COMPARISION WITH THE EFFECTS OF DIOXINS AND METHLCHOLANTHRENE
- 215 MUTAGENIC ACTIVATION OF 2- AND 3-CHLORODIBENZOFURANS BY LIVER MICROSOMES AND THE CORRELATION WITH CYTOCHROME P-450 ISOZYMES
- A04 EFFECTS OF METYRAPONE ON THE CYTOCHROME P450 MEDIATED DRUG METABOLIZING ACTIVITIES IN THE PRIMARY CULTURES OF RAT HEPATOCYTES
- Effects of blood sampling for hematological and biochemical parameters in toxicokinetic study of rat.
- STUDIES ON THE ESTABLISHMENT OF APPROPRIATE SPERMATOGENIC ENDPOINTS FOR MALE FERTILITY DISTURBANCE IN RODENT INDUCED BY DRUGS AND CHEMICALS I. NITROBENZENE
- STUDY OF EXAMINATION METHODS FOR ASSESSING MALE FERTILITY DISTURBANCES 2.THE SPERM EVALUATION USING ADRIAMYCIN
- A Pharmacokinetic and Pharmacodynamic Analysis of CPT-11 and Its Active Metabolite SN-38
- EFFECTS OF VARIOUS INDUCERS ON THE ACTIVITIES OF CYTOCHROME P-450-MIXED FUNCTION OXIDASES AND AFLATOXIN B_1 ACTIVATION IN MICROSOMES OF HAMSTER LIVERS
- EFFECTS OF TRIS (2, 3-DIBROMOPROPYL) PHOSPHATE ON THE PRENATAL AND POSTNATAL DEVELOPMENTS OF THE RATS (The 6th Meeting for the Study of Toxic Effect)
- STUDIES ON THE TERATOGENICITY OF FURYLFURAMIDE IN FETUSES AND OFFSPRING OF RATS IN RELATION TO FETAL DISTRIBUTION
- IN VITRO NEUROTOXICITY ASSAY SYSTEM BY NEURONAL CLONES (1) : EFFECTS OF CHLORDANE ON ELECTROPHYSIOLOGICAL PROPERTIES OF HYBRID NEURONAL CLONE NG 108-15
- A-15 IN VITRO TERATOGENICITY TESTING USING THE RAT EMBRYO CULTURE SYSTEM : (3) EFFECTS OF CYCLOPHOSPHAMIDE ON RAT EMBRYONIC DEVELOPMENT IN VITRO AND IN VIVO
- A-6 EFFECT OF BIS (TRIBUTYLTIN) PHTHALATE ON THE FETAL DEVELOPMENT
- Toxicity Evaluation by using primary cultured rat hepatocytes
- W4-3 Toxicity Evaluation by using primary cultured rat hepatocytes
- C12 IN VITRO TERATOGENICITY TESTING USING THE RAT EMBRYO CULTURE SYSTEM : (1) EFEECTS OF SODIUM SALICYLATE ON RAT EMBRYONIC DEVELOPMENT IN VITRO AND IN VIVO
- C03 SYNERGIC EFFECT OF MESTRANOL ON VIRILIZING ACTIVITY OF NORETHYNODREL IN FEMALE RAT FETUSES
- EFFECT OF INTRAMUSCULAR INJECTION OF DRUGS ON SERUM CPK ACTIVITY IN RABBITS
- TERATOLOGICAL STUDIES OF ZINC ETHYLPHENYLDITHIOCARBAMATE (ZEPC), A VULCANIZATION ACCELERATOR FOR RUBBERS, IN RATS
- "A-13 p-Phenylenediamines, antioxidative ingredients for rubber compound : a quantitative evaluation of their skin sensitization in guinea pig (GPMT)
- A new device for the determination of microsomal cytochrome P-450 in renal tissue preparations from various species contaminated with mitochondria and hemoglobin.