散剤調剤のし易さへの検討(1)

概要

論文の詳細を見る
There are many factors affecting practicableness of powder preparations for dispensing, such as angle of repose, angle of spatula, compressibility, flocculation, uniformity, particle diameter, specific gravity and porosity. In this study, the practicableness of powders for dividing with Konishi's automatic powder divider or pile packer and for weighing was examined by sensory evaluation. It was found out that there is a significant relationship between practicableness for dispensing and the factors above mentioned. The practicableness was also studied in terms of the powder fluidity index of Ralph L. Carr. Dividing and folding services have become convenient with an introduction of imporved automatic dividers or change of dosage form from powder to granules or fine granules. But there are some problems in dispensing granules and fine granules. Fluidity and other properties concern directly not only with the practicableness for weighing but with mixing and dividing errors and practicableness for taking drugs by patients. Therefore, such factors have to be further studied.
日本医療薬学会の論文
1979-08-20