高齢者向け新規剤形の開発 : ゼラチンで調製した乾燥ゲル層の吸水膨潤に及ぼす要因

概要

論文の詳細を見る
Investigated for the purpose of developing a new dosage form for elderly patients were the effect of the gel concentration in preparation of the dry gel, the particle size of the dry gel, and additives in preparation of the dry gel on the water absorption and swelling behavior of a dry gel layer prepared with gelatin. Three principal results were obtained, First, the dry gel layer prepared at the 10% gel concentration demonstrated the fastest water absorption and swelling rate. Second, the water absorption and swelling behavior of the dry gel layer prepared at the 10% gel concentration was not affected by the particle size of the dry gel. Third, the water absorption and swelling rate of the dry gel layer was greatly increased by the more than 10% addition of sodium citrate in the amount of gelatin.
日本医療薬学会の論文
1994-10-20