小児用安全容器の透湿性

概要

論文の詳細を見る
The water vapor permeation behavior of the child resistant package (CRP) with a press-and-turn closure, the polyethylene bottle with a screw cap and the glass bottle with a screw cap was investigated. The water vapor permeation increased in the order of the glass bottle, polyethylene bottle and CRP. The amount of water vapor permeated through the CRP showed a linear increment with the passage of time. The effect of applied sealing torques on the water vapor permeation was also investigated. There was not affect on the water vapor permeation of glass bottle and little influence on the of the polyethylene bottle. On the contrary, the water vapor permeation of the CRP showed dependency on the applied sealing torque. These results suggest that the differences in water vapor permeation were due to the specific structure of the CRP closure. Additionally revealed was that in the CRP the relationship between the log applied sealing torque and the water vapor permeation rate produced a near-straight curve.
日本医療薬学会の論文
1995-04-10