硬カプセル剤の内容医薬品とカプセルの強度との関係

概要

論文の詳細を見る
In the study on bioavailability of hard capsules, basic physical properties of hard capsules and their preparations were examined. Results of the study on the film and strength of hard capsules and their preparations, as well as on the relationship between the cap-body joint methods of capsules and physical properties of capsules, are reported in the following. The strength was largest at the ends of both cap and body of capsules, followed by that of the side and shoulder of the cap, and then the side and shoulder of the body. The thickness was largest also at the ends of the cap and body. There was a great correlation between the thickness of the film of capsules and its strength, so far as the end of the capsules is concerned. Thanks to the recent improvement, the joint method produced only a slight effect on physical properties of capsules when the pressure is applied to the ends of the cap and body.
日本医療薬学会の論文
1979-02-20