静注用γ-グロブリン製剤の検討 : 主として溶解時における起泡の比較

概要

論文の詳細を見る
Recently, different kinds of intravenous γ-globulin are introduced to medical field, where they are used in combination with antibiotics for infections, autoimmune disease, malignant tumors and so forth. γ-Globulin preparations are manufactured by various pharmaceutical companies in different prescription, method of preparation and reconstruction, and kits and containers for reconstruction. Considering the safety of drug in use, we investigated the stability and effervescence at dissolution of 5 commercial intravenous γ-globulin products, change with time in effervescence volume as well as sensitive manual test method on product handling from the standpoint of the drug management. In addition, problems related to intravenous γ-globulin in use were studied to make an overall evaluation of γ-globulin.
日本医療薬学会の論文
1981-10-20