食行動異常者の成長ホルモン分泌動態 : 特に経口糖負荷に対するparadoxical riseを中心に

概要

論文の詳細を見る
Thirty patients with eating disorder were classified into 3 groups : 1) anorexia nervosa, 2) dysorexia nervosa and 3) simple obesity groups. Nine patints belonged to the anorexia nervosa group, which was characterized by only anorexia, weight loss of more than 20% from ideal body weight and amenorrhea. Eleven patients belonged to the dysorexia nervosa group who had not only the anorexic phase but the polyphagic phase. Ten patients belonged to the simple obesity group who showed the weight gain of more than 20% from ideal body weight. Growth hormone secretions after oral glucose loads were studied in the three groups. The results were as follows : 1) Paradoxical rises of grouth hormone after oral glucose loads were found in 4 out of 11 patients with dysorexia nervosa, which is of high frequency compared with anorexia nervosa and simple obesity. These results suggest that patients with dysorexia nervosa may have some dysfunction in the satiety center of the hypothalamus. 2) Growth homone suppressions after oral glucose loads were found in 9 out of 10 patients with simple obesity. 3) The basal value of growth homone in patients with anorexia nervosa and dysorexia nervosa was signficantly higher than that in patients with simple obesity.
日本心身医学会の論文
1983-06-01