Seasonal Changes in Luteal Progesterone Concentration and mRNA Expressions of Progesterone Synthesis-related Proteins in the Corpus Luteum of Mares
スポンサーリンク
概要
- 論文の詳細を見る
Although circulating progesterone (P4) levels tend to change with the season, little is known about the seasonal changes of P4 synthesis-related proteins in the corpus luteum (CL) of mares. To examine these changes, seventy-four ovaries containing a CL were collected from Anglo-Norman mares at a local abattoir in Kumamoto, Japan (~N32°), five times during one year. The stages of the CLs were classified as early, mid and regressed by macroscopic observation of the CL and follicles. The mid CL, which had the highest P4 concentration, was used to evaluate the seasonal changes in P4 synthesis. The luteal P4 concentration and mRNA expression of luteinizing hormone receptor (LHCGR) were lowest during early winter and highest during late winter. The mRNA expressions of steroidogenic acute regulatory protein (StAR), P450 cholesterol side-chain cleavage enzyme (P450scc) and 3β-hydroxysteroid dehydrogenase/Δ5-Δ4 isomerase (3β-HSD) were lowest during early winter and increased during late winter. These results suggest that P4 synthesis in the CL is affected by the seasonal changes in the mRNA expressions of P4 synthesis-related proteins in mares.
- 2012-08-01
著者
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TAKAHASHI Masashi
National Agricultural Research Center for Kyushu Okinawa Region
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Okuda Kiyoshi
Laboratory Of Reproductive Endocrinology Graduate School Of Natural Science And Technology Okayama U
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Acosta Tomas
Laboratory Of Reproductive Endocrinology Graduate School Of Natural Science And Technology Okayama U
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Hojo Takuo
Laboratory Of Reproductive Endocrinology Graduate School Of Natural Science And Technology Okayama U
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Nambo Yasuo
Hidaka
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KOZAI Keisuke
Laboratory of Reproductive Physiology, Graduate School of Natural Science and Technology, Okayama University
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HOJO Takuo
Laboratory of Reproductive Physiology, Graduate School of Natural Science and Technology, Okayama University
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ACOSTA Tomas
Laboratory of Reproductive Physiology, Graduate School of Natural Science and Technology, Okayama University
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ACOSTA Tomas
Laboratory of Animal Genetics and Reproduction, Obihiro University of Agriculture and Veterinary Medicine
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KOZAI Keisuke
Laboratory of Reproductive Physiology, Graduate School of Environmental and Life Science, Okayama University, Okayama 700–8530, Japan
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