A Case of Ambiguous External Genitalia in a Thoroughbred Male Horse with the 63,XO/64,XY Mosaic Karyotype
スポンサーリンク
概要
- 論文の詳細を見る
A Thoroughbred colt with ambiguous external genitalia was presented for clinical and histological examinations. The colt had a short penis that faced backward between his hind limbs. The measurements of luteinizing hormone, follicle stimulating hormone, testosterone and ir-inhibin showed a tendency to increase gradually from April. Both the sex-determining region of the Y chromosome and amelogenin gene fragments were detected by the PCR method. A cytogenetic analysis revealed the 63,XO/64,XY mosaic karyotype (ratio 83:17). In autopsy, immature symmetrical subcutaneous testes were found in the inguinal regions. The testes and other accessory sex organs were histologically normal. These results add to our knowledge of chromosomal abnormality and information concerning disorders of sex development in the horse.
著者
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HIROTA Keiichi
Laboratory of Racing Chemistry
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Taya Kazuyoshi
Laboratory Of Veterinary Physiology Department Of Veterinary Medicine Faculty Of Agriculture Tokyo U
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TOZAKI Teruaki
Department of Molecular Genetics, Laboratory of Racing Chemistry
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Nambo Yasuo
Hidaka
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Ito Katsumi
Hidaka Breeders' Association
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Sato Fumio
Hidaka Training And Res. Centre Japan Racing Assoc.
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ENDO Yoshiro
Hidaka Training and Research Center, JRA
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HIROTA Keiichi
Department of Molecular Genetics, Laboratory of Racing Chemistry
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DHAKAL Pramod
Laboratory of Veterinary Physiology, Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology
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MURASE Harutaka
Hidaka Training and Research Center, Japan Racing Association
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Endo Yoshiro
Hidaka Training And Research Center Jra
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ITO Katsumi
Hidaka Horse Breeders Assosiation
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ENDO Yoshiro
Hidaka Training and Research Center, Japan Racing Association
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