Immunization of Goats against Inhibin Increased Follicular Development and Ovulation Rate
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概要
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In the present study, two experiments were conducted to induce superovulation in goats using passive and active immunization against inhibin. In the first experiment, two groups of goats were given an intravenous injection of either 10 ml normal goat serum (control; n=6) or inhibin antiserum developed against [Tyro30]-inhibin α (1-30) (passively immunized; n=6) 48 h before treatment with PGF2α. In the second experiment, two groups of goats were immunized with inhibin vaccine (actively immunized; n=5) or Freunds adjuvant (control; n=5) followed by three booster immunizations at 4 week intervals. Blood samples were collected for determination of FSH, LH, estradiol-17 β, and progesterone. Ultrasonography was used to determine ovarian activity at PGF2α injection and ovulation rate one week after estrus. In both experiments, there was a significant increase in plasma FSH concentration compared with the controls. However, the pattern of the FSH levels was different between the passively and actively immunized goats. The numbers of follicles in passively and actively immunized goats (22.4 ± 2.3 and 18.6 ± 2.1, respectively) were significantly greater than those in the controls (2.6 ± 0.4 and 2.3 ± 0.4, respectively). In addition, the ovulation rate was greater in the immunized animals compared with the controls. Therefore, either passive or active immunization against inhibin could be used to induce superovulation in goats.
- 日本繁殖生物学会の論文
- 2006-08-01
著者
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WATANABE Gen
Laboratory of Veterinary Physiology, Department of Veterinary Medicine, Faculty of Agriculture, Toky
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TAYA Kazuyoshi
Laboratory of Veterinary Physiology, Department of Veterinary Medicine, Faculty of Agriculture, Toky
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MEDAN Mohamed
Department of Theriogenology, Faculty of Veterinary Medicine, Suez Canal University
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SHARAWY Sayed
Department of Theriogenology, Faculty of Veterinary Medicine, Suez Canal University
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Taya Kazuyoshi
Laboratory Of Veterinary Physiology Department Of Veterinary Medicine Faculty Of Agriculture Tokyo U
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Taya K
Laboratory Of Veterinary Physiology Department Of Veterinary Medicine Tokyo University Of Agricultur
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SASAKI Kazuaki
Central Research Laboratory, Hitachi, Ltd.
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Watanabe Gen
Laboratory Of Veterinary Physiology Department Of Veterinary Medicine Faculty Of Agriculture Tokyo U
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Medan Mohamed
Faculty Of Veterinary Medicine Suez Canal University
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Medan Mohamed
Department Of Theriogenology Faculty Of Veterinary Medicine Suez Canal University
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Medan Mohamed
東京農工大学 農学部獣医学科獣医生理学研究室
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Sasaki Kazuaki
Central Research Laboratory Hitachi Ltd.
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Sharawy S
Department Of Theriogenology Faculty Of Veterinary Medicine Suez Canal University
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Takimoto Kazuhiro
Department Of Veterinary Science National Institute Of Health
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Medan Mohamed
エジプト
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Watanabe Gen
Laboratories Of Veterinary Physiology Dep. Of Veterinary Medicine Fac. Of Agriculture Tokyo Univ. Of
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Sakaki Kazuaki
Central Research Laboratory, Hitachi, Ltd.
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