ウシXY雌におけるeCG、hCG、GnRH-A投与前後の血中FSH、LH、inhibin、E2、P、T濃度の変化

概要

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To clarify the endocrinological characteristics of bovine gonadal hypoplasia (XY female), peripheral FSH, LH, inhibin, estradiol-17β (E2), progesterone (P) and testosterone (T) levels were measured before and after the administration of eCG, hCG and GnRH-A in the 3 bovine XY females without the Sry gene. Before the administration of hormonal drugs, the concentrations of FSH and LH were higher than in adult bulls, cows in the luteal phase and castrated bulls. On the other hand, the concentrations of inhibin and E2 were lower than those observed in the follicular phase during the estrous cycle. Concentrations of P and T were much lower than those observed in the luteal phase during the estrous cycle and in bulls. Gonads of our XY females did not respond to eCG or hCG stimulation, whereas the pituitary was highly responsive to GnRH-A in LH secretion.
2000-12-01