The Mucin Box and Signal/Anchor Sequence of Rat Neutral Ceramidase Recruit Bacterial Sphingomyelinase to the Plasma Membrane

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概要

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• Sphingolipid metabolites act as lipid mediators in various cellular events. We found that the mucin box and signal/anchor sequence of a rat neutral ceramidase recruit bacterial sphingomyelinase to the plasma membranes of mammalian cells. The mucin box-fused sphingomyelinase hydrolyzed cellular sphingomyelin efficiently to generate ceramide.

• 2011-05-23

著者

• Takahashi N

  Plant Functions Laboratory Riken

• Nakano Takeshi

  Riken Advanced Sci. Inst.

• Ito Makoto

  Department Of Cardiovascular And Respiratory Medicine Shiga University Of Medical Science

• Nakagawa Tetsuto

  Department Of Bioscience And Biotechnology Division Of Bioresource And Bioenvironmental Sciences Gra

• Sueyoshi Noriyuki

  Department Of Bioscience And Biotechnology Graduate School Of Bioresource And Bioenvironmental Scien

• Ito Masaki

  Science And Biotechnology Graduate School Of Bioresource And Bioenvironmental Sciences Kyusyu Univer

• NAKANO Takeshi

  The Institute of Physical and Chemical Research (RIKEN)

• Tani M

  Science And Biotechnology Graduate School Of Bioresource And Bioenvironmental Sciences Kyusyu Univer

• Tani Motohiro

  Department Of Bioscience And Biotechnology Division Of Bioresource And Bioenvironmental Sciences Gra

• Nakagawa T

  Department Of Bioscience And Biotechnology Division Of Bioresource And Bioenvironmental Sciences Gra

• Takahashi Nobuyuki

  Hokkaido University Of Education

• Nakano Takeshi

  Plant Functions Lab.

• Sueyoshi Noriyuki

  Department Of Bioscience And Biotechnology Graduate School Of Bioresource And Bioenvironmental Scien

• Ito Makoto

  Department Of Bioscience And Biotechnology Graduate School Of Bioresource And Bioenvironmental Scien

• ITO Makoto

  Department of Bioresources, Faculty of Agriculture, Ehime University

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