Silencing of the gene for homeobox protein HOXB13 by siRNA confers resistance to methylmercury on HEK293 cells
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概要
- 論文の詳細を見る
Methylmercury is an environmental pollutant that causes severe central nervous system disorders. We searched for transcription factors involved in the development of methylmercury toxicity and found that the decreased expression of a homeobox protein, HOXB13, in HEK293 cells conferred strong resistance to methylmercury.
- 2010-12-01
著者
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Takahashi Tsutomu
Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Toho
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Naganuma Akira
Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Toho
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Naganuma Akira
Lab. Of Molecular And Biochemical Toxicology Graduate School Of Pharmaceutical Sciences Tohoku Univ.
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HWANG Gi-Wook
Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Toho
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Hwang Gi-wook
Laboratory Of Molecular And Biochemical Toxicology Graduate School Of Pharmaceutical Sciences Tohoku
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Naganuma A
Tohoku Univ. Sendai Jpn
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RYOKE Katsunori
Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Toho
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Naganuma Akira
Laboratory Of Molecular And Biochemical Toxicology Graduate School Of Pharmaceutical Science Tohoku
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Takahashi Tsutomu
Laboratory Of Kampo-pharmaceutics Faculty Of Pharmacy Osaka Ohtani University
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Naganuma Akira
Laboratory Of Molecular And Biochemical Toxicology Graduate School Of Pharmaceutical Sciences Tohoku
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Naganuma Akira
Department Of Public Health And Molecular Toxicology School Of Pharmaceutical Sciences Kitasato Univ
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Hwang Gi-wook
Laboratory Of Molecular And Biochemical Toxicology Graduate School Of Pharmaceutical Sciences Tohoku
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Ryoke Katsunori
Laboratory Of Molecular And Biochemical Toxicology Graduate School Of Pharmaceutical Sciences Tohoku
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Takahashi Tsutomu
Laboratory Of Molecular And Biochemical Toxicology Graduate School Of Pharmaceutical Sciences Tohoku
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Takahashi Tsutomu
Laboratory Of Molecular And Biochemical Toxicology Graduate School Of Pharmaceutical Sciences Tohoku
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