ラット肝臓ミクロソームにおける, 硫酸マグネシウムによるチトクロームP450 2C, 3Aの活性化およびブピバカインの酸化代謝に及ぼす影響

スポンサーリンク

概要

• 論文の詳細を見る
• 2006-06-30

著者

• Matsumoto Y

  Department Of Clinical Pharmacology And Toxicology Showa Pharmaceutical University

• Shimizu Makiko

  Showa Pharmaceutical University

• SAITO Miwako

  Department of Anesthesiology, Kitasato University School of Medicine

• OKUTOMI Toshiyuki

  Department of Anesthesiology, Kitasato University School of Medicine

• MATSUMOTO Yoshiaki

  College of Pharmacy, Nihon University

• YAMAZAKI Hiroshi

  Showa Pharmaceutical University

• HOKA Sumio

  Department of Anesthesiology, Kitasato University School of Medicine

• 松本 宣明

  Division Of Applied Life Science Graduate School Of Engineering Sojo University

• Saito Miwako

  Department Of Anesthesiology Kitasato University School Of Medicine

• Okutomi Toshiyuki

  Department Of Anesthesiology Kitasato University School Of Medicine

• Hoka Sumio

  Department Of Anesthesiology And Critical Care Medicine Faculty Of Medicine Kyushu University

• Matsumoto Yoshiaki

  College Of Pharmacy Nihon University

関連論文

• 肝P450等の薬物代謝酵素活性を指標とした日本発新規ヒト型モデル動物"マイクロミニブタ"の非臨床試験における高い将来性
• P-283 救命病棟における薬剤師業務活動
• P-345 抗 MRSA 用剤の治療効果に及ぼす栄養因子の検討
• 日本人肝におけるフラビン含有モノオキシゲナーゼ3発現の個人差 : 肝転写因子との相関
• Complex Mechanism Underlying Transcriptional Control of the Haplotyped Flavin-containing Monooxygenase 3 (FMO3) Gene in Japanese : Different Regulation between Mutations in 5'-Upstream Distal Region and Common Element in Proximal Region
• P-36 非定常状態を含むフェニトインの体内動態解析ツールの開発
• Sulfating-Activity and Stability of cDNA-Expressed Allozymes of Human Phenol Sulfotransferase, ST1A31 (^Arg) and ST1A32 (^His), Both of Which Exist in Japanese as Well as Caucasians^1
• 高気圧酸素療法を施した患者の抗がん薬カルボプラチン血漿中濃度測定用HPLC法について
• 非ステロイド性抗炎症剤の薬物動態と薬効の評価 : 健康成人, 外来高齢者, 寝たきり高齢者の比較
• ハイブリッドリポソームを用いた大腸がんの肝転移抑制に関する基礎研究
• コトンラット胃腫瘍由来腹水性がん細胞株に対するハイブリッドリポソームの増殖抑制効果
• 糖含有三成分系ハイブリッドリポソームの物性と制がん効果に関する基礎研究
• 焼酎粕からの抗腫瘍性物質の生産
• ハイブリッドリポソーム単独投与によるマウス神経芽腫肝転移抑制効果
• アポトーシス誘導ハイブリッドリポソームによるがん治療
• 副作用のないがん治療への挑戦--ハイブリッドリポソーム・生理活性物質 (特集 次世代バイオテクノロジーの展開)
• アポトーシス誘導リポソームのがん治療
• 糖尿病モデルラットを用いたインシュリン含有複合脂質膜の経口治療に関する基礎的研究
• リポソームによるがん治療と診断 (特集 先端治療システム開発の最前線)
• 1C15-5 キノコ抽出物の培養がん細胞に対する増殖抑制効果
• 抗がん剤を含まないハイブリッド型リポソームのみによるin Vivoでのがん化学療法
• アポトーシス誘導ハイブリッドリポソームの癌治療効果 (化学と生物学の接点がつくるNewバイオテクノロジー) -- (遺伝子発現をあやつる)
• 複合脂質膜の制がんメカニズムと臨床への応用
• 焼酎蒸留粕 (廃液) を利用した新素材転換システムに関する基礎研究 : がん細胞増殖抑制効果
• ハイブリッド型リポソームの種々の腫瘍細胞に対する特異的増殖抑制効果
• 肺癌モデルマウスに対するハイブリッド型リポソームの治療効果
• 温度感受性ハイブリッド型リポソームの創製と薬物送達システムへの応用
• 制がん性ハイブリッド型リポソームのアポトーシス誘導
• 担癌モデルマウスに対するハイブリッド型リポソームの治療効果
• Possibility of Influence of Midazolam Sedation on the Diagnosis of Brain Death: Concentrations of Active Metabolites after Cessation of Midazolam
• CHDF 施行患者におけるミダゾラム体内動態に関する検討
• 低体温療法施行患者におけるミダゾラム体内動態に関する検討
• Missense and Nonsense Mutations of the Flavin-containing Monooxygenase 3 Gene in a Japanese Cohort
• Stop codon mutations in the flavin-containing monooxygenase 3 (FMO3) gene responsible for trimethylaminuria in a Japanese population.
• 日本人トリメチルアミン尿症の原因となるフラビン含有モノオキシゲナーゼ3遺伝子の新規遺伝子変異
• Pharmacokinetic Investigation of Increased Efficacy Against Malignant Gliomas of Carboplatin Combined With Hyperbaric Oxygenation
• Correlation between the Physicochemical Property of Some Nonsteroidal Anti-inflammatory Drugs and Changes in Adenosine Triphosphate, Glutathione and Hemoglobin in Rat Erythrocytes(Biopharmacy)
• Evaluation of Pharmacokinetic parameters of Cibenzoline after Administration of a Single Oral Dose in Healthy Volunteers
• Evaluation of Pharmacokinetic Parameters of Cibenzoline after Administration of a Single Oral Dose in Healthy Volunteers
• Determination of concentrations of flecainide in human serum by high-performance liquid chromatography on a fluorocarbon-bonded silica gel column
• 2SP5-06 がん細胞膜の揺らぎをターゲットとする制がん効果(2SP5 生体分子の揺らぎをはかる,第47回日本生物物理学会年会)
• ラット肝臓ミクロソームにおける, 硫酸マグネシウムによるチトクロームP450 2C, 3Aの活性化およびブピバカインの酸化代謝に及ぼす影響
• Population Pharmacokinetic-Pharmacodynamic Modeling of TF-505 Using Extension of Indirect Response Model by Incorporating a Circadian Rhythm in Healthy Volunteers(Biopharmacy)
• 4'-Hydroxylation of Flurbiprofen by Rat Liver Microsomes in Fasting and Feeding Conditions(Biopharmacy)
• Effects of Aspirin and/or Salicylate on Hydrolysis and Glucuronidation of Indomethacin in Rat Erythrocytes and Hepatocytes
• Glucuronidation of Propofol and Its Analogs by Human and Rat Liver Microsomes
• Testicular Toxicity of Mono-n-Butyl Phthalate and Related Phthalates on Bound Iron in Rat Red Blood Cells
• Possible Origin of Rat Testicular Atrophy Induced by Di-n-Butyl Phthalate : Changes in the Activities of Some Enzymes during Rat Testis Perfusion under a Hypoxic Condition and with Mono-n-Butyl Phthalate
• A Computer Program for Pharmacokinetics Based on Maximum Likelihood Estimation Using the Gamma Distribution with a Probability Density Function : Comparison with the Normal Distribution
• Pharmacokinetics of Fluconazole and Fosfluconazole after Intraperitoneal Administration to Peritoneal Dialysis Rats
• 新規ドラッグデリバリ-システムの開発 (特集 新しい研究開発と課題)
• CARDIOPULMONARY BAROREFLEX IS AFFECTED BY AGING : PROCEEDINGS OF THE 47th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY : Peripheral Circulation
• Study on the Discrepancy in Responses Given by Patients to Questions Regarding Subjective Symptoms
• Study on Factors that Contribute to Poor Patient Compliance with Medication in Japan
• Nanoparticles of Hybrid Liposomes for the Inhibition of Breast Tumor Growth along with Apoptosis
• Specific Fixed Aqueous Layer of Three-component Hybrid Liposomes Related to Inhibition of Hepatoma Cells Growth
• Induction of Apoptosis by Hybrid Liposomes for Human Breast Tumor Cells along with Activation of Caspases(Medicinal Chemistry)
• Marked Inhibitory Effects of Extracts from Barley-Koji Miso Encapsulated in Hybrid Liposomes on the Growth of Human Stomach Tumor Cells in Vitro
• Inhibitory Effects of Extracts from Shochu Distillation Remnants on the Growth of Human Stomach Tumor Cells
• Inhibitory Effects of Extracts from Peels of Citrus natsudaidai Encapsulated in Hybrid Liposomes on the Growth of Tumor Cells in Vitro(Medicinal Chemistry)
• Brain oxygenation monitored by near-infrared spectroscopy during recovery from hemorrhagic shock
• Overexpression of Ca^-permeable AMPA receptor promotes delayed cell death of hippocampal CA1 neurons following transient forebrain ischemia
• HIGH SALT INTAKE REDUCES VENOUS DISTENSIBILITY IN SALT SENSITIVE HYPERTENSIVE PATIENTS : Hypertension (II) : 46th Annual Scientific Meeting, Japanese Circulation Society
• A High-Performance Liquid Chromatographic Determination of Cibenzoline Using Solid-Phase Extraction
• Bonitos with Low Content of Malodorous Trimethylamine as Palliative Care for Self-reported Japanese Trimethylaminuria Subjects
• Induction of Apoptosis by Hybrid Liposomes without Antitumor Drugs toward Human Breast Tumor Cells
• Steric-Control for the Enantioselective Hydrolysis of Amino Acid Esters in Hybrid Membrane Systems
• Cyclodextrin-Mediated Deacylation of Amino Acid Esters with Marked Stereoselectivity
• Remarkably Enhanced Inhibitory Effects of Three-Component Hybrid Liposomes Including Sugar Surfactants on the Growth of Lung Carcinoma Cells
• Method of ranking of heart valve characteristics at mitral position based on statistical model analysis
• Marked Therapeutic Effect of Dimyristoylphosphatidylcholine Liposomes on Carcinoma Mice Model in Vivo
• Tube obstruction of CobraPLA in a patient with fixed flexed neck
• Impaired acquisition of skilled behavior in rotarod task by moderate depletion of striatal dopamine in a pre-symptomatic stage model of Parkinson's disease
• Clinical characteristics of perioperative coronary spasm : reviews of 115 case reports in Japan
• Anesthetic management of a patient with a history of Batista procedure for dilated cardiomyopathy undergoing gastric surgery
• Noninvasive assessment of left ventricular pressure-area relationship using transesophageal echocardiography and tonometry during cardiac and abdominal aortic surgery
• Preoperative non-invasive assessment of stress response to breath-holding test
• Changes in left ventricular end-diastolic area, end-systolic wall stress, and fractiona area change during anesthetic induction with propofol or thiamylal
• Effect of nicardipine on vascular capacitance: comparison with sodium nitroprusside during induced hypotension
• Pharmacokinetics and Variation in the Clearance of Oxycodone and Hydrocotarnine in Patients with Cancer Pain(Miscellaneous)
• Relationship between Serum Fentanyl Concentration and Transdermal Fentanyl Dosage, and Intra-individual Variability in Fentanyl Concentration after Application of Fentanyl Patches in Patients with Cancer Pain
• Spinal anesthesia using a continuous spinal catheter for cesarean section in a parturient with prior surgical correction of scoliosis
• Patient-controlled epidural analgesia during labor using ropivacaine and fentanyl provides better maternal satisfaction with less local anesthetic requirement
• デュシェンヌ型筋ジストロフィーに伴う高度な脊柱変形に対する第三世代脊椎インストゥルメントを用いた手術的治療の成績
• Intracellular Responses of Hybrid Liposomes against Leukemia Cells Related to Apoptosis with Antitumor Activity
• Novel Potassium Chennel Activators. II. Synthesis and Pharmacological Evaluation of 3,4-Dihydro-2H-1,4-benzoxazine Derivatives : Modificaiton of the Aromatic Part
• Comparison of the effects of sevoflurane and isoflurane anesthesia on the maternal-fetal unit in sheep
• Novel Potassium Channel Activators. III. Synthesis and Pharmacological Evaluation of 3,4-Dihydro-2H-1,4-benzoxazine Derivatives : Modification at the 2 Position
• Development of a Computer Program, MDGP, for Population Pharmacokinetic Analysis Written Using ANSI C Language on Wide Platforms
• Acute Drug Poisoning at Critical Care Departments in Japan
• Two-year results for scoliosis secondary to Duchenne muscular dystrophy fused to lumbar 5 with segmental pedicle screw instrumentation
• Does the Inhibitor of Nitric Oxide Synthase Improve Hemodynamics and Oxygen Metabolism in Hemorrhagic Hypotension?
• Chemotherapy with Hybrid Liposomes for Melanomatosis
• Optimization and validation of a high-performance liquid chromatographic method with UV detection for the determination of pyrrole-imidazole polyamides in rat plasma
• Comparison of Cytochrome P450 3A Enzymes in Cynomolgus Monkeys and Humans
• Clustering of Lipid Rafts in Plasma Membranes by Hybrid Liposomes for Leukemia Cells along with Apoptosis
• イタドリ生理活性物質含有ハイブリッドリポソームのリンパ腫細胞に対する増殖抑制効果
• REMARKABLE INHIBITORY EFFECTS OF HYBRID LIPOSOMES ON THE GROWTH OF HL-60 CELLS COUPLED TO INDUCTION OF APOPTOSIS
• 人工細胞膜の制がん効果 (化学工学の新潮流)
• 人工膜および細胞膜の揺らぎとがん治療

もっと見る 閉じる

スポンサーリンク