Facilitated Disassembly of Polyplexes Composed of Self-assembling Amphiphilic Polycations Enhances the Gene Transfer Efficacy

スポンサーリンク

概要

• 論文の詳細を見る
• 2005-11-05

著者

• MURAKAMI Akira

  Department of Ophthalmology, Juntendo University School of Medicine

• Ishihara Kazuhiko

  Department of Regulation Biochemistry, Kitasato University School of Medicine

• KITAGAWA Tatsuya

  Department of Polymer Science and Engineering, Kyoto Institute of Technology

• YAMAOKA Tetsuji

  Department of Polymer Science and Engineering, Kyoto Institute of Technology

• Ishihara Kazuhiko

  Department Of Materials Engineering The University Of Tokyo

• Murakami Akira

  Department Of Polymer Science And Engineering Kyoto Institute Of Technology

• IWASE Reiko

  Department of Bioscience, Teikyo University of Science and Technology

• Iwase Reiko

  Department Of Biosciences Teikyo University Of Science And Technology

• Ishihara Kazuhiko

  Department Of Biochemistry Kitasato University Graduate School Of Medical Sciences

• Murakami Akira

  Department Of Biomolecular Engineering Kyoto Institute Of Technology

• Yamaoka Tetsuji

  Department Of Biomedical Engineering Advanced Medical Engineering Center National Cardiovascular Cen

• Kitagawa Tatsuya

  Department Of Polymer Science And Engineering Kyoto Institute Of Technology

• Murakami Akira

  Department Of Biomolecular Engineering Graduate School Of Science And Technology Kyoto Institute Of

• MURAKAMI Akira

  Department of Polymer Science and Engineering, Kyoto Institute of Technology

• Murakami Akira

  Departmemt of Cardiology, Surugadai Nihon University Hospital

関連論文

• A Novel Mutation (967-970+2)delAAAGGT in the Choroideremia Gene Found in a Japanese Family and Related Clinical Findings
• Chromosomal AmpC β-lactamase-mediated β-lactam resistance of gram-negative bacteria enhances host inflammatory mediator production via nucleotide-binding oligomerization domain 1
• ROLE OF RENAL SYMPATHETIC NERVE IN DEVELOPMENT OF HYPERTENSION IN SPONTANEOUSLY HYPERTENSIVE RAT (SHR) : PROCEEDINGS OF THE 47th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY : Hypertension
• THE ROLE OF THE AUTONOMIC NERVOUS ACTIVITY IN ESSENTIAL HYOERTENSION : Cardiac Surgery II, Hemodialysis, Hypertension II : IInd Auditorium : Proceedings of the 43rd Annual Meeting of the Japanese Circulation Society, Tokyo, 1979
• STUDIES ON HYPERTENSION: EFFECTS OF SALT ADMINISTRATION ON HUMORAL FACTORS AND HISTOLOGICAL CHANGES IN SHR : IInd Auditorium
• Anti-tumor Promoting Activity of Bufadienolides from Kalanchoe pinnata and K.daigremontiana×tubiflora
• In Vitro Absorption and Metabolism of Nobiletin, a Chemopreventive Polymethoxyflavonoid in Citrus Fruits
• An Avocado Constituent, Persenone A, Suppresses Expression of Inducible Forms of Nitric Oxide Synthase and Cyclooxygenase in Macrophages, and Hydrogen Peroxide Generation in Mouse Skin
• Inhibition by (-)-Persenone A-related Compounds of Nitric Oxide and Superoxide Generation from Inflammatory Leukocytes
• Suppression of N-Nitrosomethylbenzylamine-induced Rat Esophageal Tumorigenesis by Dietary Feeding of 1'-Acetoxychavicol Acetate
• Screening for the In Vitro Anti-tumor-promoting Activities of Edible Plants from Malaysia
• Identification of Zerumbone in Zingiber zerumbet Smith as a Potent Inhibitor of 12-O-Tetradecanoylphorbol-13-acetate-induced Epstein-Barr Virus Activation
• Inhibitory Effects of Curcumin and Tetrahydrocurcuminoids on the Tumor Promoter-induced Reactive Oxygen Species Generation in Leukocytes in vitro and in vivo
• Chemoprevention of Azoxymethane-induced Rat Colon Carcinogenesis by a Xanthine Oxidase Inhibitor, 1'-Acetoxychavicol Acetate
• Auraptene, a Citrus Coumarin, Inhibits 12-O-Tetradecanoylphorbol-13-acetate-induced Tumor Promotion in ICR Mouse Skin, Possibly through Suppression of Superoxide Generation in Leukocytes
• Identitication of Pheophorbide a and Its Related Compounds as Possible Anti-tumor Promoters in the Leaves of Neptunia oleracea
• Chemopreventive Effect of a Xanthine Oxidase Inhibitor, 1'-Acetoxychavicol Acetate, on Rat Oral Carcinogenesis
• Stem Cell Factor in the Tear Fluid of Vernal Keratoconjunctivitis Patients
• Mast Cells in Pterygium : Number and Phenotype
• Inhibitory Effects of 1'-Acetoxychavicol Acetate on N-Nitrosobis(2-oxopropyl)-amine-induced Initiation of Cholangiocarcinogenesis in Syrian Hamsters
• Experimantal Study of Inclusive Reaction ^C(γ,π^-) at 44.2°
• Possible Anti-tumor Promoting Properties of Edible Plants from Thailand, and Identification of an Active Constituent, Cardamonin, of Boesenbergia pandurata
• A Novel Mutation in the Cornea-Specific Keratin 12 Gene in Meesmann Corneal Dystrophy
• Novel Mutation (V505D) of the TGFBI Gene Found in A Chinese Family with Lattice Corneal Dystrophy, Type I
• Mutations in the Membrane Component, Chromosome 1, Surface Marker 1 (M1S1) Gene in Gelatinous Drop-like Corneal Dystrophy
• Analysis of COL8A2 Gene Mutation in Japanese Patients with Fuchs' Endothelial Dystrophy and Posterior Polymorphous Dystrophy
• Mutation Analysis of the TGFBI Gene in Vietnamese with Granular and Avellino Corneal Dystrophy
• OPA1 Gene Mutations in Japanese Patients with Bilateral Optic Atrophy Unassociated with Mitochondrial DNA Mutations at nt 11778, 3460, and 14484
• Multiplex Polymerase Chain Reaction for Detection of Herpes Simplex Virus Type 1, Type 2, Cytomegalovirus, and Varicella-Zoster Virus in Ocular Viral Infections
• A Novel Mutation of the TGFBI Gene Found in a Vietnamese Family with Atypical Granular Corneal Dystrophy
• Transferrin-Polyethylenimine Conjugate, FuGENE6 and TransIT-LT as Nonviral Vectors for Gene Transfer to the Corneal Endothelium
• MISSENSE MUTATION OF RHODOPSIN GENE CODON 15 FOUND IN JAPANESE AUTOSOMAL DOMINANT RETINITIS PIGMENTOSA
• A Case of Oculodentodigital Dysplasia Syndrome with Novel GJA1 Gene Mutation
• Long-term Follow-up of Two Sisters with Leber's Hereditary Optic Neuropathy
• Expression and Distribution of Junctional Adhesion Molecule-1 in the Human Cornea
• Preparation and properties of ProNectin F-coated biodegradable hollow fibers
• Effect of Cation Content of Polycation-type Gene Carriers on in vitro Gene Transfer
• Characterization of Rat Gastric Mucins Using a Monoclonal Antibody, RGM23, Recognizing Surface Mucous Cell-Type Mucins
• Rat Gastric Mucins Recognized by Monoclonal Antibodies RGM21 and HIK1083: Isolation of Mucin Species Characteristic of the Surface and Glandular Mucosa
• Expression of Stem Cell Factor in Pterygium
• Aldosterone Synthesis and Cytokine Production in Human Peripheral Blood Mononuclear Cells
• Anti-inflammatory Effect of Spironolactone on Human Peripheral Blood Mononuclear Cells
• 1'-Acetoxychavicol Acetate as a Potent Inhibitor of Tumor Promoter-induced Epstein-Barr Virus Activation from Languas galanga, a Traditional Thai Condiment
• Monitoring Cellular Events in Living Mast Cells Stimulated with an Extremely Small Amount of Fluid on a Microchip
• Synthesis and Properties of Segmented Poly(urethane-urea)s Containing Phosphorylcholine Moiety in the Side-Chain
• Preparations of Aromatic Diamine Monomers and Copolyamides Containing Phosphorylcholine Moiety and the Biocompatibility of Copolyamides
• Anti-tumor Promotion with Food Phytochemicals: A Strategy for Cancer Chemoprevention
• Difference in Prognostic Factors between Stage IB and II Uterine Cervical Carcinoma Patients Treated with Radical Hysterectomy and Postoperative Radiation Therapy
• Heterozygous Ala137Pro Mutation in Keratin 12 Gene Found in Japanese with Meesmann's Corneal Dystrophy
• Reaction of Various Lectins to Mucin Derived from the Different Layers of Rat Gastric Mucosa : Comparison of Enzyme-Linked Lectin Binding Assay with Lectin Histochemistry
• Rat Gastric Mucous Gel Layer Contains Sialomucin Not Produced by the Stomach
• Selection of RNA-binding Peptides Containing an Arg-rich Motif
• Design of RNA-Binding Oligopeptides Based on Information of RNA-Binding Protein
• Apoptosis in Retinal Ganglion Cell Decrease in Human Glaucomatous Eyes
• Biocompatibility of MPC : in vivo evaluation for clinical application
• Bacterial Reduction of Azo Compounds as a Model Reaction for the Degradation of Azo-Containing Polyurethane by the Action of Intestinal Flora
• Enhanced Expression of Foreign Gene Transferred to Mammalian Cells in vitro Using Chemically Modified Poly(L-lysine)s as Gene Carriers
• Beating behavior of primary neonatal cardiomyocytes and cardiac-differentiated P19. CL6 cells on different extracellular matrix components
• Intraperitoneal administration of paclitaxel solubilized with poly(2-methacryloxyethyl phosphorylcholine-co n-butyl methacrylate) for peritoneal dissemination of gastric cancer
• Higher Water Intrusion Property on Novel Porous Matrix Composed of Bioinspired Polymer Stereocomplex for Tissue Engineering
• Immunohistochemical Characterization of Epithelial Cells Implanted in the Flap-Stroma Interface of the Cornea
• Possible Inhibitor of Tumor Promotion and Related Polyphenol from Lophira alata, a Medicinal Plant in Tropical West Africa(Organic Chemistry)
• PB67 SYNTHESIS OF CAPPED OLIGORIBONUCLEOTIDES BY USE OF PROTECTED 7-METHYLGUANOSINE 5'-DIPHOSPHATE DERIVATIVES
• Electrical Transport Ability of Nanostructured Potassium-Doped Titanium Oxide Film
• Recovery of mucin content in surface layer of rat gastric mucosa after HCI-aspirin-induced mucosal damage
• Mucosal Protection by Shokyo, a Crude Drug, against Ethanol-induced Gastric Damage in Rat
• Intracellular Enzyme-responsive Fragmentation of Nonviral Gene Carriers Leads to Polyplex Destabilization and Enhanced Transgene Expression
• Facilitated Disassembly of Polyplexes Composed of Self-assembling Amphiphilic Polycations Enhances the Gene Transfer Efficacy
• Solid-Phase Synthesis of Amide-Linked Oligoribonucleosides and Their Properties
• Ex Vivo Transfer of Smad7 Decreases Damage to the Corneal Endothelium After Penetrating Keratoplasty
• Disodium Cromoglycate Inhibits Capsaicin-Induced Eosinophil Infiltration of Conjunctiva Independent of Mast Cells
• Evaluation of Conditions for Release of Mucin-Type Oligosaccharides from Glycoproteins by Hydrazine Gas Treatment
• Chalcone Tetramers, Lophirachalcone and Alatachalcone, from Lophira alata as Possible Anti-tumor Promoters
• Timing-controlled Decompaction of Polyplexes In Vivo Greatly Enhances Transgene Expression
• In Vitro Shoot Development of Eucalyptus citriodora on Rockwool in the Film Culture Vessel under CO_2 Enrichment
• Naphthyridine-tethered Oligodeoxyribonucleotides : Dye/DNA Conjugates for Homogeneous SNPs Assays
• In vitro and ex vivo blood compatibility study of 2-methacryloyloxyethyl phosphorylcholine (MPC) copolymer-coated hemodialysis hollow fibers
• Water-Soluble 2-Methacryloyloxyethyl Phosphorylcholine Copolymer as a Novel Synthetic Blocking Reagent in Immunoassay System
• Polymeric Lipid Nanosphere Consisting of Water-Soluble Poly(2-methacryloyloxyethyl phosphorylcholine-co-n-butyl methacrylate)
• UCST-Type Cononsolvency Behavior of Poly(2-methacryloxyethyl phosphorylcholine in the Mixture of Water and Ethanol)
• Dimension f Poly(2-methacryloyloxyethyl phosphorylcholine) in Aqueous Solutions with Various Ionic Strength
• Effects of indomethacin on the rat small intestinal mucosa : immunohistochemical and biochemical studies using anti-mucin monoclonal antibodies
• Modification of PLA Scaffolds Using Bioactive Peptide-Oligo (Lactic Acid) Conjugates
• Stage IV ovarian clear cell adenocarcinoma treated effectively by chemotherapy with etoposide and cisplatin (EP)
• A Water-Soluble Phospholipid Polymer as a New Biocompatible Synthetic DNA Carrier
• Apoptosis After Butyrate-Induced Differentiation in Retinoblastoma Cell Line Y-79
• Clinical Findings in a Choroideremia Patient Who Underwent Vitrectomy for Retinal Detachment Associated with Macular Hole
• Spatial distribution of intraperitoneally administrated paclitaxel nanoparticles solubilized with poly (2-methacryloxyethyl phosphorylcholine-co n-butyl methacrylate) in peritoneal metastatic nodules
• Physicochemical delivery of amphiphilic copolymers to specific organelles
• Association of gastric acid and mucus secretion level with low-dose aspirin-induced gastropathy
• Live-Cell-Driven Insertion of a Nanoneedle
• Chain dimension of polyampholytes in solution and immobilized brush states
• OPA1 mutations in Japanese patients suspected to have autosomal dominant optic atrophy
• Surface Modification of SiO2 Microchannels with Biocompatible Polymer Using Supercritical Carbon Dioxide
• Effects of Z-300, a New Histamine H2-Receptor Antagonist, on Mucin Biosynthesis in Rat Gastric Mucosa.
• Anti-inflammatory Effect of Spironolactone on Human Peripheral Blood Mononuclear Cells
• Appearance of specific mucins recognized by monoclonal antibodies in rat gastric mucosa healing from HCl-induced gastric mucosal damage
• Detection of microtubules in vivo using antibody-immobilized nanoneedles(CELL AND TISSUE ENGINEERING)
• The helical flow pump with a hydrodynamic levitation impeller
• Elution of Two Separated Peaks after Injection of a Small Sample Volume Using an Autosampler

もっと見る 閉じる

スポンサーリンク