Depressive State With Anxiety in Repeated Cold-Stressed Mice in Forced Swimming Tests
スポンサーリンク
概要
- 論文の詳細を見る
The effects of various types of stress and drugs were studied to assess mouse performance in forced swimming tests, following characterization of SART (specific alternation of rhythm in environmental temperature) stress. Immobility time in the test decreased in mice subjected to SART, acute cold and restraint stress. No change was noted due to chronic cold stress or repeated fasting. The shortened time did not recover even 24 hr after the end of SART and chronic restraint stress. The time in SART-stressed mice finally recovered at 5 - 7 days. Shortening of immobility time in SART-stressed mice was inhibited by diazepam and repeated imipramine but not by lithium carbonate. In chronic restraint-stressed mice, this time was inhibited by repeated lithium carbonate but not diazepam or imipramine. SART stress would thus appear related to anxiety and depression and may be useful for detecting new types of antidepressants.
- 社団法人 日本薬理学会の論文
- 1999-02-01
著者
-
NISHIKAWA Hiroyuki
Department of Chemistry, Graduate School of Science, Tokyo Metropolitan University
-
Nojiri Hiroyuki
Graduate School Of Pure And Applied Sciences University Of Tsukuba
-
Itoh Eiji
Department Of Pharmacology Faculty Of Pharmacy Kinki University
-
Itoh Eiji
Department Of Bioresources Science Faculty Of Agriculture Kochi University
-
Itoh E
Kochi Univ. Nankoku Jpn
-
Hata Toshiyuki
Biotechnology Fukuyama University
-
Nishikawa H
Graduate School Of Pure And Applied Sciences University Of Tsukuba
-
Nishikawa H
Tokyo Metropolitan Univ. Tokyo Jpn
-
Nishikawa H
Department Of Pharmacology Faculty Of Pharmaceutical Sciences Kinki University
-
HATA Taeko
Department of Pharmacology, Faculty of Pharmaceutical Sciences, Kinki University
-
WATANABE Akiko
Department of Pharmacology, Faculty of Pharmaceutical Sciences, Kinki University
-
NISHIKAWA Hiroyuki
Graduate School of Pure and Applied Sciences, University of Tsukuba
-
Nishikawa Hiroyuki
Graduate School Of Pure And Applied Sciences University Of Tsukuba
-
Nishikawa Hiroyuki
Department Of Breast And Endocrine Surgery St. Marianna University School Of Medicine
-
Hata Taeko
Department Of Pharmacology Faculty Of Pharmaceutical Sciences Kinki University
-
Watanabe Akiko
Department Of Pharmacology Faculty Of Pharmaceutical Sciences Kinki University
-
Nishikawa Hiroyuki
Department of Applied Physics and Chemistry, The University of Electro-Communications, Chofu, Tokyo 182-8585, Japan
-
Hata Taeko
Biotechnology, Fukuyama University
関連論文
- Specific Alternation of Rhythm in Temperature (SART) Stress-Induced Irritable Bowel Syndrome-Like Changes in Mice and Effects of Drugs
- Development and Applications of Magnetooptical Measurement System Equipped with a Rotational Resonant Cavity in the Millimeter-Wave Region
- ac Calorimetry and EPR Study on Metal-Insulator Transition and Glass Transition in an Organic Conductor with Double-Column Structure, (DIMET)_2BF_4 : Condensed Matter: Electronic Properties, etc.
- Calorimetric Study of Metal-Insulator Transition in (DIMET)_2I_3 : Phase Separation in Ternary Mixtures
- In-Plane Angular Effect of Magnetoresistance of Quasi-One-Dimensional Organic Metals,(DMET)_2AuBr_2 and (TMTSF)_2ClO_4
- Fine Structure of In-Plane Angular Effect of Magnetoresistance of (DMET)_2I_3
- Sharp Anomaly in Magnetoresistance of the Spin-Density-Wave State of (TMTSF)_2PF_6
- Anomalous Angular Dependence of Magnetoresistance of an Organic Superconductor, (DMET)_2I_3
- Current-Voltage Characteristics of Porphyrin/C60 Multi-Layered Organic Photovoltaic Device with and without Hole Collection Oxide Films
- Proteomic analysis of immature murine melanocytes at different stages of maturation : A crucial role for calreticulin
- Model Analysis of Anomalies in Highly Oriented Pyrolytic Graphite Images by Scanning Tunneling Microscope in Air
- Model Analysis of Current-Mode Images of Highly Oriented Pyrolytic Graphite by Scanning Tunneling Microscope in Air
- Observation of Surface Corrugation of Highly Oriented Pyrolylic Graphite by Scanning Tunneling Microscope in Air
- A Role for Corticotropin-Releasing Factor in Repeated Cold Stress-Induced Anxiety-Like Behavior during Forced Swimming and Elevated Plus-Maze Tests in Mice (Pharmacology)
- Anxiety-Like Behavior in Elevated Plus-Maze Tests in Repeatedly Cold-Stressed Mice
- Depressive State With Anxiety in Repeated Cold-Stressed Mice in Forced Swimming Tests
- Production and Characterization of Heteroatom-encapsulated Metallofullerene, CaHo@C_
- Quantum Criticality in Reduced π-Donor System (MeDH-TTP)_2AsF_6(Condensed matter: electronic structure and electrical, magnetic, and optical properties)
- Molecular Conductor Based on Reduced π-System Donor : Insulating State of (MeDH-TTP)_2AsF_6
- Selective Extraction of Endohedral Metallofullerenes Using a Mixed Solvent of Triethylamine and Acetone
- Isolation and Characterization of a New Isomer of Ca@C_
- Dichalcogenane Derivatives of Methylenedithio(ethylenedithio)tetrathiafulvalene (MET) and a Derived Metallic Cation-Radical Salt with Screwed Donor Stacks
- Metal-Insulator,SDW,and Glass Transitions in the Organic Conductors,(DMET)_2BF_4 and (DMET)_2ClO_4,Studied by ac Calorimetry^
- Heat Capacity of TTF-TCNQ and TSF-TCNQ
- Structure and Physical Properties of (TMEO-TTP)_2Au( CN )_2
- Ethylenedioxy Substituted 2,5-Bis(1',3'-dithiol-2'-ylidene)-1,3,4,6-tetrathiapentalenes and Their Conducting Salts
- Structure and Electrical Properties of MeDTET Salts
- 2,5-Bis(1', 3'-dithiol-2'-ylidene)-1, 3, 4, 6-tetrathiapentalene and its Related Unsymmetrical Donors
- Structure and Conducting Properties of TMET-TTP Radical-Cation Salts
- Bis(methylthio) Substituted Unsymmetrical 2,5-Bis(1',3'-dithiol-2'-ylidene)-1,3,4,6-tetrathiapentalenes
- Preparation, Crystal Structure and Electrical Properties of 2-Cyclopentanylidene-1,3-dithiolo[4,5-d]tetrathiafulvalene Derivatives
- Methylthio Substituted 2,5-Bis(1',3'-dithiol-2'-ylidene)-1,3,4,6-tetrathiapentalene. A Bis-Fused Tetrathiafulvalene
- Physicochemical and Crystal Structure Analyses of the Antidiabetic Agent Troglitazone
- Physicochemical Analyses of Phase Transition and Dehydration Processes of a New Oral 1β-Methylcarbapenem Antibiotic Agent, CS-834
- Ether Extract of Fetal Cakf Serum Protects Cultured Rat Cortical Neurons against Glutamate Cytotoxicity
- Alkoxo-bridged Cobalt(II) Cube and Its Radical Adduct
- Effects of Molecular Association in the Radical-Cations of 1,8-Bis (ethylenedithiotetrathiafulvalenyl) naphthalene^1
- 4, 5-Diiodo-4', 5'-ethylenedioxytetrathiafulvalene and Its Metallic Radical Salts
- Crystal stucture of a 1β-Methylcarbapenem Antibiotic, Pivaloyloxymethyl(1R, 5S, 6S)-6-[(R)-1-hydroxyethyl]-1-methyl-2-[(R)-5-oxopyrolidin-3-yl]-1-carbapen-2-em-3carboxylate, CS-834 Dihydrate
- Effects of Particle Size on the Monolayer Structure of Nanoparticles Formed via a Wet-Coating Process
- Multiscale Simulation of Two-Dimensional Self-Organization of Nanoparticles in Liquid Film
- Lipase-Catalyzed Asymmetric Synthesis of Desprenyl-carquinostatin A and Descycloavandulyl-lavanduquinocin
- Effects of Some β-Adrenoceptor Antagonists on Orthostatic Hypotension in Repeatedly Cold-(SART-) Stressed Rats(Pharmacology)
- Effects of AF-DX116 and Other Muscarinic Receptor Antagonists on Orthostatic Hypotension in Autonomic Imbalanced (SART-Stressed) Rats
- In Situ Observation of the Four-step Dehydration Process of the 1β-Methylcarbapenem Antibiotic CS-834 Crystal by X-Rays
- The Absolute Configuration of (+)-Oxopropaline D by Theoretical Calculation of Specific Rotation and Asymmetric Synthesis
- Crystal Structure of an Antidiabetic Agent, (±)-5-[4-(6-Hydroxy-2,5,7,8-tetramethylchroman-2-ylmethoxy)benzyl]-2,4-dioxothiazollidine, Troglitazone Dihydrate
- Blood Pressure and Heart Rate Are Increased by AF-DX 116, a Selective M_2 Antagonist, in Autonomic Imbalanced and Hypotensive Rats Caused by Repeated Cold Stress
- Crystal and Molecular Structure of a 1β-Methylcarbapenem Antibiotic, CS-834
- Crystal and Molecular Structure of (±)-(5R)-[4-(6-Hydroxy-(2R)-2, 5, 7, 8-tetramethylchroman-2-ylmethoxy)benzyl] -2, 4-dioxothiazolidine Monohydrate
- Insecticidal Activity of α-Methylene-γ-butyrolactone against Several Insect Pests
- Precursor of α-Methylene-γ-butyrolactone Involved in the Insecticidal Activity of Thunberg Spiraea, Spiraea thunbergii
- Insecticidal Component in Thunberg Spiraea, Spiraea thunbergii, against Thrips palmi
- Gamma-Ray-Induced Loss of Er^-Doped Silica-Core Optical Fiber
- Role of Point Defects in Dielectric Breakdown of SiO_2 Formed by Plasma-Enhanced Chemical Vapor Deposition of Tetraethoxysilane
- Clinical Significance of Estrogens in Chronic Aggressive Hepatitis
- Photovoltaic Properties of Organic p-n Junction Devices Consisting of Phthalocyanine and n-Type Porphyrin Deposited on an n-Type TiO_2 Layer
- Effect of Lithium Perchlorate Doping and Prebiasing on Electrical Conduction of Molecularly Doped Poly (N-vinylcarbazole) Light Emitting Diode
- Effects of TGF-β1 on Extracellular Matrix Formation in Rat Clonal Dental Pulp Cells
- Ultraviolet Photoelectron Spectroscopy and Surface Potential of π-conjugated Langmuir-Blodgett Films on Gold Metal Electrode
- Electrostatic Phenomena in π-conjugated Langmuir-Blodgett Films on Metal Electrodes
- EFFECT OF GINSENG-20S-PROSAPOGENIN ON TISSUE BLOOD FLOW MEASURED BY THE HYDROGEN CLEARANCE METHOD IN SYMPATHICOTONIC- OR PARASYMPATHICOTONIC-TYPE STRESSED MICE
- PHARMACOLOGICAL ACTIONS OF GINSENG SAPONIN IN STRESS MICE
- EXPERIMENTAL PHARMACOLOGICAL STUDY ON PARTIAL SYMPATHICOTONIA IN RESTRAINT AND WATER IMMERSION STRESSED ANIMALS
- ANALGESIC AND OTHER PHARMACOLOGIC ACTIONS OF SAIKO-SAPONIN IN REPEATED COLD STRESSED (SART STRESSED) ANIMALS
- Enhancement of the Open-Circuit Voltage and Hole Conduction of Tetraphenyl Porphyrin/C60 Multilayered Photovoltaic Device by the Insertion of Oxide Hole Collection Layers
- Short-distance Walking Responses of Thrips palmi KARNY(Thysanoptera:Thripidae)to Tomato Leaves
- EFFECTS OF EXOGENOUS STIMULI AND CENTRALLY ACTING DRUGS ON GALVANIC SKIN RESPONSES IN RATS
- Electrical properties of conducting polymer/CNT composite films prepared on thin titanium dioxide layer(Evaluation of organic materials)
- Electrical properties of conducting polymer /CNT composite films prepared on thin titanium dioxide layer
- Field Emission from Carbon-Nanotube-Dispersed Conducting Polymer Thin Film and Its Application to Photovoltaic Devices
- Interfacial Electronic Phenomena and Capacitance -Voltage Characteristics of Phthalocyanine Langmuir-Blodgett Films
- Surface Potential of Polyimide Langmuir-Blodgett Films Induced by Photoirradiation
- Blood Coagulation and Fibrinolysis in SART-Stressed (Repeated Cold-Stressed) Rats and Drug Effects on the Altered Hemostatic Parameters
- Patterning of Polyimide/Single-Walled Carbon Nanotube Composite and Its Electrical Properties
- Analgesic Mechanism of Neurotropin: Relation to the Serotonergic System and Influence of Spinal Cord Transection
- Impairment of Passive Avoidance Performance in SART-Stressed Mice and the Action of Drugs
- The Abnormal Open-Field Behavior of SART-Stressed Rats and Effects of Some Drugs on It
- Changes in Platelet Count and Related Parameters in SART-Stressed Mice and the Action of Administered Neurotropin
- Changes of Tissue Blood Flow in Mice Loaded with SART (Repeated Cold) Stress or Restraint and Water Immersion Stress and the Effect of Administered Neurotropin
- STUDIES ON THE SITE OF ACTION OF NEUROTROPIN IN EXPERIMENTS ON DENERVATION-SUPERSENSITIVITY OF THE DUODENUM AND VAS DEFERENS OF RATS AND MICE
- EXPERIMENTAL PARTIAL SYMPATHICOTONIA, AND EFFECTS OF SOME DRUGS ON IT IN RESTRAINT AND WATER IMMERSION STRESSED ANIMALS
- Current-Voltage Characteristics of Porphyrin/C_ Multi-Layered Organic Photovoltaic Device with and without Hole Collection Oxide Films
- Calculation of the Surface Potential across Langmuir-Blodgett Films with Polar Molecules
- Field Emission from Carbon-Nanotube-Dispersed Conducting Polymer Thin Film and Its Application to Photovoltaic Devices
- Relationship between Work Function of Hole Collection Electrode and Temperature Dependence of Open-Circuit Voltage in Multilayered Organic Solar Cells
- Fabrication of Inverted Bulk-Heterojunction Organic Solar Cell with Ultrathin Titanium Oxide Nanosheet as an Electron-Extracting Buffer Layer
- Photovoltaic Properties of Bulk-Heterojunction Organic Solar Cell with Ultrathin Titanium Oxide Nanosheet as Electron Selective Layer
- Fabrication of Polymer-Based Transistors with Carbon Nanotube Source Drain Electrodes Using Softlithography Techniques
- Fabrication of Double Layered Hybrid Solar Cells Consisting of Low-Temperature Anatase Titanium Oxide and Conducting Polymer
- Photovoltaic Properties of Organic p–n Junction Devices Consisting of Phthalocyanine and n-Type Porphyrin Deposited on an n-Type TiO2 Layer
- Electrical Properties of Heat-Treated C60 Field Effect Transistor Prepared on Polyimide Gate Insulator
- A characteristic pattern of active avoidance behavior in SART-stressed rats.
- Changes of total acetylcholine content and the activity of related enzymes in SART (repeated cold)-stressed rat brain and duodenum.
- Electrocorticogram in rats loaded with SART stress (repeated cold stress).
- Photovoltaic Properties of Bulk-Heterojunction Organic Solar Cell with Ultrathin Titanium Oxide Nanosheet as Electron Selective Layer (Special Issue : Solid State Devices and Materials)
- Changes in CNS Levels of Serotonin and Its Metabolite in SART-Stressed(Repeatedly Cold-Stressed)Rats.
- Methacholine- and adrenaline-induced arrhythmias in repeatedly cold-stressed mice.
- Effect of Lithium Perchlorate Doping and Prebiasing on Electrical Conduction of Molecularly Doped Poly (N-vinylcarbazole) Light Emitting Diode
- Subsensitivity to substance P in SART-stressed mice.