Cationic Liposome-Mediated Efficient Induction of Type I Interferons by a Low Dose of Poly I:Poly C in Mouse Cell Lines
スポンサーリンク
概要
- 論文の詳細を見る
- Japanese Biochemical Societyの論文
- 1998-10-01
著者
-
Hashida Mitsuru
Department Of Basic Pharmaceutics Faculty Of Pharmaceutical Sciences Kyoto University
-
Hashida Mitsuru
京都大学 薬学研究科病態情報薬学
-
Hashida Mitsuru
Dep. Of Drug Delivery Res. Graduate School Of Pharmaceutical Sciences Kyoto Univ. 46-29 Yoshidashimo
-
Hashida Mitsuru
Inst. Of Integrated Cell-material Sciences (icems) Kyoto Univ.
-
Watanabe Y
Department Of Molecular Biopharmacy And Genetics Graduate School Of Pharmaceutical Sciences Tohoku U
-
Hashida Mitsuru
Graduate School Of Pharmaceutical Sciences Kyoto University
-
TAKAKURA Yoshinobu
Department of Drug Delivery Research, Graduate School of Pharmaceutical Sciences, Kyoto University
-
HASHIDA Mitsuru
京大院薬
-
WATANABE Yoshihiko
Molecular Microbiology, Graduate School of Pharmaceutical Sciences, Kyoto University
-
OKAMOTO Sachiko
Departments of Drug Delivery Research, Kyoto University
-
Okamoto Sachiko
Departments Of Drug Delivery Research Kyoto University
-
Takakura Yoshinobu
Department Of Basic Pharmaceutics Faculty Of Pharmaceutical Sciences Kyoto University
-
Takakura Yoshinobu
Department Of Drug Delivery Research Graduate School Of Pharmaceutical Sciences Kyoto University
-
Watanabe Yoshifumi
Department Of Biomolecular Engineering Tokyo Institute Of Technology
-
Watanabe Yoshihiko
Department of Molecular Biopharmacy and Genetics, Graduate School of Pharmaceutical Sciences, Tohoku University
関連論文
- Biliary Excretion of Mitomycin C Dextran Conjugates in Relation of Physicochemical Characteristics of Carrier Dextran
- Intracellular Trafficking Is the Important Process That Determines the Optimal Charge Ratio on Transfection by Galactosylated Lipoplex in HepG2 Cells(Biopharmacy)
- Effect of the Particle Size of Galactosylated Lipoplex on Hepatocyte-Selective Gene Transfection after Intraportal Administration(Biopharmacy)
- Effect of Low-Molecular-Weight β-Cyclodextrin Polymer on Release of Drugs from Mucoadhesive Buccal Film Dosage Forms(Biopharmacy)
- Lipid Carrier Systems for Targeted Drug and Gene Delivery
- Analysis of Hepatic Disposition of Native and Galactosylated Polyethylenimine Complexed with Plasmid DNA in Perfused Rat Liver
- 5-Fluorouracil Derivatives. XXII. Synthesis and Antitumor Activities of 1-Carbamoyl-5-fluorouracils
- Effect of Co-administration of Cationic Macromolecules on the In Vivo Disposition and situ Renal Disposition Characteristics of rhIL-11
- Hepatic Disposition Characteristics of Recombinant Human Interleukin-11 (rhIL-11) in the Perfused Rat Liver
- Development of the inclusive evaluation method for the percutaneous absorption III : Prediction of human dermal concentration of chemicals in various vehicles
- Prediction of skin permeability of compounds from their molecular structure
- 2D- and 3D-QSAR of carrier-mediated transport of beta-lactam antibiotics in Caco-2 cells
- Prediction of Human Skin Permeability Using a Combination of Molecular Orbital Calculations and Artificial Neural Network
- QSPR analysis on inhibition of recombinant CYP3A4 activity by structurally diverse compounds using genetic algorithm combined partial least squares method
- Theoretical Analysis of the Effect of Cutaneous Metabolism on Skin Permeation of Parabens Based on a Two-Layer Skin Diffusion/Metabolism Model
- Pharmacokinetic analysis of ^I-labeled medium chain fatty acid as a radiopharmaceutical for hepatic function based on beta-oxidation
- Effect of Medium-Chain Glycerides on the Membrane Transport of D-Glucose and Sulfanilic Acid in the Intestinal Brush-Border Membrane Vesicles
- EFFECT OF MEDIUM-CHAIN GLYCERIDES (MGK^[○!R]) ON THE INTESTINAL ABSORPTION AND THE HEPATOBILIARY TRANSPORT OF BROMTHYMOL BLUE
- Pharmacokinetic considerations regarding non-viral cancer gene therapy
- Pharmacokinetic Evaluation of Biodistribution Data Obtained with Radiolabeled Proteins in Mice
- Pharmacokinetic Analysis of the in Vivo Disposition of Chemically Modified Proteins in Rats : Effect of Radiolabeling Method
- STUDY ON THE ACTION OF PERCUTANEOUS PENETRATION ENHANCERS : EFFECT ON VARIOUS DRUGS WITH DIFFERENT PHYSICOCHEMICAL PROPERTIES
- Analysis of Drug Penetration through Skin Considering Donor Concentration Decrease
- EFFECTS OF MITOMYCIN C, 5-FLUOROURACIL AND CYCLOPHOSPHAMIDE ON DRUG ABSORPTION, ENZYME ACTIVITIES AND MUCOSAL LIPID COMPOSITION OF INTESTINE
- BIOPHARMACEUTICAL STUDIES ON ANTITUMOR DRUG-INDUCED GASTROINTESTINAL DAMAGES
- Role of Tyrosine and Tryptophan in Chemically Modified Serum Albumin on Its Tissue Distribution(Biopharmacy)
- Control of Plasma Cholesterol-Lowering Action of Probucol with Various Lipid Carrier Systems
- Effects of Methyl-β-cyclodextrin Treatment on Secretion Profile of Interferon-β and Zonula Occuludin-1 Architecture in Madin–Darby Canine Kidney Cell Monolayers
- Secretion Mode and Subcellular Localization of Human Interferon-β Exogenously Expressed in Porcine Renal Epithelial LLC-PK_1 Cells(Biopharmacy)
- Exogenous Expression of Interferon-β in Cultured Brain Microvessel Endothelial Cells(Biochemistry/Molecular Biology)
- Expression and Visualization of a Human Interferon-β-Enhanced Green Fluorescent Protein Chimeric Molecule in Cultured Cells (Biochemistry/Molecular Biology)
- Cationic Liposome-Mediated Efficient Induction of Type I Interferons by a Low Dose of Poly I:Poly C in Mouse Cell Lines
- Unique Cytokine Production Profile Following Stimulation with DNA in Macrophages from NZB/W F_1 Mice(Miscellaneous)
- Transport Characteristics of Ebastine and Its Metabolites across Human Intestinal Epithelial Caco-2 Cell Monolayers
- Cellular Interaction and in Vitro Antitumor Activity of Lipophilic Mitomycin C Prodrugs(Pharmaceutical)
- Key Physiological Phenomena Governing Transgene Expression Based on Tissue Pressure-Mediated Transfection in Mice
- EVALUATION OF DRUG DISPOSITION IN BRAIN BY MOMENT ANALYSIS (II)
- Enhanced Gene Transfection in Macrophages by Histidine-Conjugated Mannosylated Cationic Liposomes
- Relationship between Drug Release of DE-310, Macromolecular Prodrug of DX-8951f, and Cathepsins Activity in Several Tumors(Biopharmacy)
- Hydrogen peroxide-mediated nuclear factor κB activation in both liver and tumor cells during initial stages of hepatic metastasis
- Influence of Cholesterol Composition on the Association of Serum Mannan-Binding Proteins with Mannosylated Liposomes(Analytical Biochemistry)
- Tissue-specific in vivo gene transfer characteristics following direct injection of plasmid DNA
- IMMUNOLOGICAL CONTROL OF DRUG ABSORPTION FROM THE GASTROINTESTINAL TRACT : EFFECT OF LOCAL ANAPHYLAXIS ON THE INTESTINAL ABSORPTION OF LOW MOLECULAR WEIGHT DRUGS IN THE RAT
- DRUG ABSORPTION FROM THE GASTROINTESTINAL TRACT AND IMMUNITY : THE MECHANISM OF THE DECREASED ABSORPTION OF SALICYLIC ACID DURING SYSTEMIC ANAPHYLAXIS. II
- DRUG ABSORPTION FROM THE GASTROINTESTINAL TRACT AND IMMUNITY : THE MECHANISM OF THE DECREASED ABSORPTION OF SALICYLIC ACID DURING SYSTEMIC ANAPHYLAXIS.I
- Deconvolution Analysis for Absorption and Metabolism of Aspirin in Microcapsules
- Effect of Vehicle Properties on Skin Penetration of Emedastine
- Molecular and Pharmacokinetic Properties of 222 Commercially Available Oral Drugs in Humans
- Nonviral Approaches Satisfying Various Requirements for Effective in Vivo Gene Therapy
- Tissue Distribution of ^In-Labeled Uricase Conjugated with Charged Dextrans and Polyethylene Glycol
- CONTROL OF IN VIVO FATE OF PROTEIN DRUGS USING CHEMICAL MODIFICATION WITH SUGARS
- INTESTINAL ABSORPTION OF HAPTENS IN RATS IMMUNIZED WITH PROTEIN-HAPTEN CONJUGATE : COMPARISON OF SULFANILIC ACID WITH P-AMINOBENZOIC ACID
- EVALUATION OF ABSORPTIVE BARRIER TO PEPTIDES AND IMPROVEMENT OF MUCOSAL ABSORPTION OF PEPTIDES BY VARIOUS APPROACHES
- Design and Evaluation of Monoclonal Antibody-Antitumor Agent Conjugate
- Cellular Interaction and in Vitro Antitumor Effect of Various Mitomycin C Prodrugs in Mitomycin C-Resistant L1210 Leukemia Cell Lines(Pharmaceutical)
- EFFECT OF TEMPERATURE ON INTESTINAL TRANSFER AND TISSUE UPTAKE OF SULFANILAMIDE AND AMINOPROPYRON IN VITRO
- CELLULAR INTERACTION AND ANTITUMOR ACTIVITY OF MITOMYCIN C PRODRUGS
- URINARY EXCRETION CHARACTERISTICS OF A POLYMERIC PRODRUG OF MITOMYCIN C, MITOMYCIN C-DEXTRAN CONJUGATE
- ENHANCED LYMPHATIC DELIVERY OF MIYOMYCIN C BY POLYMERIC MODIFICATION
- Deformation Behaviour of Softened Celluloid under Complex Loading : Along Orthogonal Bi-linear Stress Trajectory
- Correlation of Induction of ATP Binding Cassette Transporter A5 (ABCA5) and ABCB1 mRNAs with Differentiation State of Human Colon Tumor(Molecular and Cell Biology)
- mRNA Expression of the ATP-Binding Cassette Transporter Subfamily A (ABCA) in Rat and Human Brain Capillary Endothelial Cells(Biochemistry/Molecular Biology)
- Effect of Polycyclic Aromatic Hydrocarbons on Generation and Efflux of Glutathione Conjugates in Primary Cultured Alveolar Epithelial Cells
- In Silico Approaches for Predicting ADME Properties of Drugs
- Preparation of an Artificial Cell Cycle Progressor with a Novel Mechanism
- Biodistribution Characteristics of Surface Charge Improved Lysine Dendrimers after Intravenous Injection in Mice
- mRNA Expression and Amino Acid Transport Characteristics of Cultured Human Brain Microvascular Endothelial Cells (hBME)
- ANTITUMOR ACTIVITY OF LIPOPHILIC PRODRUGS OF MITOMYCIN C ENTRAPPED IN LIPOSOME OR O/W EMULSION
- DEVELOPMENT OF LIPOPHILIC MITOMYCIN C PRODRUGS AND THEIR APPLICATION TO LIPID DISPERSION SYSTEMS
- Enhancement of antiproliferative activity of interferons by RNA interference-mediated silencing of SOCS gene expression in tumor cells
- Analysis Methods and Recent Advances in Nonlinear Pharmacokinetics from In Vitro through In Loci to In Vivo
- Histogram Analysis of Pharmacokinetic Parameters by Bootstrap Resampling from One-point Sampling Data in Animal Experiments
- A Racemization Test in Peptide Synthesis Using 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium Chloride (DMT-MM)
- Analysis of IFN-γ-Induced Cell Cycle Arrest and Cell Death in Hepatocytes^1
- Liver-Derived Matrix Metalloproteinase-9 (Gelatinase B) Recruits Progenitor Cells from Bone Marrow into the Blood Circulation
- Callosal commissural neurons of Dab1 deficient mutant mouse, yotari
- Development of a Simple System for Dehydrocondensation Using Solid-Phase Adsorption of a Water-Soluble Dehydrocondensing Reagent (DMT-MM)
- Direct Evidence of Macrophage Differentiation from Bone Marrow Cells in the Liver: A Possible Origin of Kupffer Cells
- PC57 SYNTHESIS OF INOSITOL POLYPHOSPHATES
- Bovine Serum Albumin as a Lyoprotectant for Preparation of DNA Dry Powder Formulations Using the Spray-Freeze Drying Method
- Evaluation of Long-Term Gene Expression in Mouse Liver Using PhiC31 Integrase and Hydrodynamic Injection
- Combination of Bubble Liposomes and High-Intensity Focused Ultrasound (HIFU) Enhanced Antitumor Effect by Tumor Ablation
- Factors Influencing the Surface Modification of Mesenchymal Stem Cells with Fluorescein-Pegylated Lipids