Development of Label-Free Bioaffinity Sensor Using a Lumped-Constant Microwave Resonator Probe
スポンサーリンク
概要
- 論文の詳細を見る
A novel label-free bioaffinity sensor using a lumped-constant microwave resonator was developed. A gold probe with a spherical tip immobilizing anti-chicken egg albumin antibody or anti-human albumin antibody on its surface was connected to the resonator and inserted into a flow cell to monitor the target antigen binding. The sensor showed specific sensitivity against its target antigen evidenced by the change of resonance frequency after the antigen injection. The large frequency shift observed during the injection of antigen solution was ascribed to the change of solution dielectric constant which showed a systematic increase with antigen concentration.
- 2011-01-25
著者
-
Cho Yasuo
Research Institute Of Electrical Communication Tohoku University
-
Chikyow Toyohiro
Advanced Electric Materials Center, National Institute for Materials Science (NIMS), 1-1 Namiki, Tsukuba, Ibaraki 305-0044, Japan
-
Nishino Taito
Nissan Chemical Industries, Ltd., Funabashi, Chiba 274-8507, Japan
-
Okazaki Noriaki
Research Institute of Electrical Communication, Tohoku University, Sendai 980-8577, Japan
関連論文
- Multiferroism at Room Temperature in BiFeO_3/BiCrO_3(111) Artificial Superlattices
- New Functions of Scanning Nonlinear Dielectric Microscopy -Higher-Order Measurement and Vertical Resolution-
- Measurement of the Ferroelectric Domain Distributions Using Nonlinear Dielectric Response
- Theoretical and Experimental Study on Nanoscale Ferroelectric Domain Measurement Using Scanning Nonlinear Dielectric Microscopy
- Determination of the Polarities of ZnO Thin Films on Polar and Nonpolar Substrates Using Scanning Nonlinear Dielectric Microscopy
- Quantitative Measurement of Linear and Nonlinear Dielectric Characteristics Using Scanning Nonlinear Dielectric Microscopy
- Theoretical Analysis of Surface Acoustic Wave Propagation Characteristics under Strained Media and Applications for High Temperature Stable High Coupling Surface Acoustic Wave Substrates
- Observation of Ultrathin Single-Domain Layers Formed on LiTaO_3 and LiNbO_3 Surfaces Using Scanning Nonlinear Dielectric Microscope with Submicron Resolution
- Simultaneous Observation of Ferroelectric Domain Patterns by Scanning Nonlinear Dielectric Microscope and Surface Morphology by Atomic Force Microscope
- Quantitative Measurement of Linear Dielectric Constant Using Scanning Nonlinear Dielectric Microscopy with Electro-Conductive Cantilever
- Fundamental Study of Surface Layer on Ferroelectrics by Scanning Nonlinear Dielectric Microscopy
- Observations of Domain Structure and Ferroelectricity in Bi(Ni_Ti_)O_3 Ceramics Fabricated by High-pressure Sintering
- Acoustic Wave Devices Composed of Periodically Poled $Z$-Cut LiTaO3 Plate Using Edge Reflection
- Scanning Nonlinear Dielectric Microscopy with Contact Sensing Mechanism for Observation of Nanometer Sized Ferroelectric Domains
- Scanning Nonlinear Dielectric Microscope with Submicron Resolution
- Development of Label-Free Bioaffinity Sensor Using a Lumped-Constant Microwave Resonator Probe
- Observation of Polarization Distribution on Si(111) Surface by Scanning Nonlinear Dielectric Microscopy
- In-Plane Distribution of Phase Transition Temperature of KTa1-xNbxO3 Measured with Single Temperature Sweep
- Surface Acoustic Wave Paramagnetic Resonance in Iron Doped-LiNbO_3 : Physical Acoustics
- Electrostrictive and Third-Order Dielectric Constants of Lithium Niobate : C: Single Crystals
- Determination of Electrostrictive and Third-Order Dielectric Constants of Piezoelectric Ceramic
- A Surface Acoustic Wave Elastic Convolver using a KNbO_3 Single Crystal Substrate
- Effect of Y content in (TaC)1-xYx gate electrodes on flatband voltage control for Hf-based high-k gate stacks (Special issue: Dielectric thin films for future electron devices: science and technology)
- Three-Dimensional Measurement for Absolute Value of Polarization Angle by Scanning Nonlinear Dielectric Microscopy
- Cross-Sectional Observation of Nano-Domain Dots Formed in Congruent Single-Crystal LiTaO_3
- Epitaxial PbTiO3 Thin Films on SrTiO3(100) and SrRuO3/SrTiO3(100) Substrates Deposited by a Hydrothermal Method
- Effect of Annealing on Implanted Ga of Diamond-Like Carbon Thin Films Fabricated by Focused-Ion-Beam Chemical Vapor Deposition
- Nanodomain Formation on Ferroelectrics and Development of Hard-Disk-Drive-Type Ferroelectric Data Storage Devices
- Ferroelectric Single Crystal Recording Media Fabricated by Polarization Controlled Wet Etching Process
- Characterization of Metal/High-$k$ Structures Using Monoenergetic Positron Beams
- Observation of Nanoscale Ferroelectric Domains Using Super-Higher-Order Nonlinear Dielectric Microscopy
- Guiding Principle of Energy Level Controllability of Silicon Dangling Bonds in HfSiON
- Modified Oxygen Vacancy Induced Fermi Level Pinning Model Extendable to P-Metal Pinning
- Surface Nitridation of $c$-Plane Sapphire Substrate by Near-Atmospheric Nitrogen Plasma
- Characterization of Deposited Materials Formed by Focused Ion Beam-Induced Chemical Vapor Deposition Using AuSi Alloyed Metal Source
- Effect of Annealing on Mechanical Properties of Materials Formed by Focused Au or Si Ion-Beam-Induced Chemical Vapor Deposition Using Phenanthrene
- Scanning Nonlinear Dielectric Microscopy Nano-Science and Technology for Next Generation High Density Ferroelectric Data Storage
- Ferroelectric Data Recording Using Servo-Controlled Tracking Technique
- Evaluation of Bit Error Rate for Ferroelectric Data Storage
- Ultrahigh-Density Ferroelectric Data Storage Using Scanning Nonlinear Dielectric Microscopy
- Combinatorial Investigation of ZrO2-Based Dielectric Materials for Dynamic Random-Access Memory Capacitors
- Observation of Antiparallel Polarization Reversal Using a Scanning Nonlinear Dielectric Microscope
- Investigation of Three-Dimensional Domain Structure in LiTaO3 by Scanning Nonlinear Dielectric Microscopy
- Observation of Surface Polarization Distribution Using Temperature-Controlled Scanning Nonlinear Dielectric Microscopy
- Higher Order Nonlinear Dielectric Imaging Using Scanning Nonlinear Dielectric Microscopy
- High-Density Ferroelectric Recording Using Diamond Probe by Scanning Nonlinear Dielectric Microscopy
- Fundamental Study on Nano Domain Engineering Using Scanning Nonlinear Dielectric Microscopy
- Nanodomain Manipulation for Reduction of Bit Error Rate in Terabit/Inch2-Class Ferroelectric Data Storage
- Ultrahigh-Density Ferroelectric Data Storage Based on Scanning Nonlinear Dielectric Microscopy
- Fundamental Studies on Scanning Electron-Beam Dielectric Microscopy
- New Functions of Scanning Nonlinear Dielectric Microscopy —Higher-Order Measurement and Vertical Resolution—
- Simultaneous Observation of Ferroelectric Domain Patterns by Scanning Nonlinear Dielectric Microscope and Surface Morphology by Atomic Force Microscope
- Piezoelectric Performance and Domain Structure of Epitaxial PbTiO3 Thin Film Deposited by Hydrothermal Method
- Cross-Sectional Observation of Nano-Domain Dots Formed in Congruent Single-Crystal LiTaO3
- Nanosecond Switching of Nanoscale Ferroelectric Domains in Congruent Single-Crystal LiTaO3 Using Scanning Nonlinear Dielectric Microscopy