Peptide synthesis in alcohol solvents by the mixed anhydride method using dimethylphosphinothioyl chloride.
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概要
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The formation and coupling of the dimethylphosphinothioic mixed anhydrides of protected amino acids can be performed in alcohol solvents. Sparingly soluble protected C-terminal segments of vasoactive intestinal peptide (VIP) up to the heptapeptide stage were synthesized by this technique and fully characterized.
- 公益社団法人 日本化学会の論文
著者
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IKEDA Shigeru
Department of Computer and Mathematical Sciences, Graduate School of Information Sciences, Tohoku Un
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Saito Takashi
Department Of Agronomy Faculty Of Agriculture Tohoku University
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UEKI Masaaki
Department of Applied Chemistry, Science University of Tokyo
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Ueki Masaaki
Department of Anesthesia, Nishiwaki Municipal Hospital:Department of Anesthesia and Perioperative Medicine, Kobe University
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Oyamada Hidekazu
Department of Applied Chemistry, Faculty of Science, Science University of Tokyo
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Oyamada Hidekazu
Department of Applied Chemistry, Science University of Tokyo
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Saito Takashi
Department of Applied Chemistry, Science University of Tokyo
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Sasaya Jun
Department of Applied Chemistry, Science University of Tokyo
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