Syntheses of cationic mononucleotide analogs and their interaction with polynucleotide and polynucleotide analogs.
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概要
- 論文の詳細を見る
Cationic mononucleotide analogs were synthesized through a quaternization reaction of <I>N</I>-halogenoethylated derivatives of nucleic acid bases or 5′-halogeno-5′-deoxynucleoside. When they interacted with polynucleotide and polynucleotide analogs with negative charges, base-base interactions were observed. The interactions between complementary bases were stronger than the others. It is suggested that an anionic field originating from the polynucleotide or polynucleotide analog contributes to the interaction of complementary bases.
- 公益社団法人 日本化学会の論文
著者
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Konishi Yoshiyuki
Department Of Biology Faculty Of Science Chiba University
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SHIMIDZU Takeo
Department of Molecular Engineering, Graduate School of Engineering, Kyoto University
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Yamana Kazushige
Department Of Applied Chemistry Himeji Institute Of Technology
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Murakami Akira
Department Of Biomolecular Engineering Graduate School Of Science And Technology Kyoto Institute Of
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Yamana Kazushige
Department of Hydrocarbon Chemistry, Faculty of Engineering, Kyoto University
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