Synthesis of 4, 4'-(Tetramethylenedicarbonyldiamino)-bis(1-decylpyridinium bromide) and Its Antimicrobial and Deodorant Characteristics

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概要

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• A new bis-quaternary ammonium compound (bis-QAC), 4, 4'-(tetramethylenedicarbonyldiamino) bis (1-decylpyridinium bromide) (D-136) was synthesized, and its antimicrobial and deodorant characteristics were studied. A vinyl chloride polymer sheet containing D-136 (D-136 sheet) was prepared for practical use because D-136 exhibited a wide and effective antimicrobial spectrum of activity against both bacteria and fungi. The antibacterial and antifungal efficiency of the D-136 sheet was estimated according to the film covering method and the test for fungus resistance. Results showed that the growth of both bacteria and fungi was inhibited on the D-136 sheet. Furthermore, a model test for the deodorant efficiency of water-absorbing resins (SAP) containing D-136 (D-136 SAP) was done on the assumption that it might be applied for use in disposable diapers. To prevent the offensive odor arising from excreted urine in disposable diapers, it is necessary to inhibit the propagation of ureahydrolyzing bacteria in the water-absorbing layer. The microbe used for the experiment was <I>Proteus mirabilis</I> IFO 3849 which produces an enzyme (urease) capable of degrading urea and other compounds present in human urine to ammonia, methylamine and the like. As for the result of the model test, the generation of ammonia from human urine was inhibited on D-136 SAP.

• 日本防菌防黴学会の論文
• 2001-09-20

著者

• Maeda Takuya

  Department Of Biological Science And Technology Faculty Of Engineering The University Of Tokushima

• Ohkura Kazuto

  Department Of Biological Science And Technology Faculty Of Engineering The University Of Tokushima

• Ohkura Kazuto

  Department Of Applied Biological Sciences School Of Agricultural Sciences Nagoya University

• Yoshida Munehiro

  Takamatsu Works Inui Corporation

• Ohno Kosei

  Faculty Of Pharmaceutical Sciences Health Sciences University Of Hokkaido

• Yoshida M

  Takamatsu Works Inui Corporation

• NAGAMUNE Hideaki

  Department of Biological Science and Technology, Faculty of Engineering, The University of Tokushima

• OKAZAKI KIYO

  Faculty of Human Life Science, Shikoku University

• NAMBA TETSUTO

  Takamatsu Works, Inui Corporation

• Okazaki K

  Faculty Of Human Life Science Shikoku University

• Kourai Hiroki

  Department Of Biological Science And Technology Faculty Of Engineering The University Of Tokushima

• Namba Tetsuto

  Takamatsu Works Inui Corporation

• Kunikata Kensei

  Takamatsu Works Inui Corporation

• Nagamune Hideaki

  Department Of Biological Science And Technology Faculty Of Engineering The University Of Tokushima

• Tsuchiya Hiroshi

  Takamatsu Works Inui Corporation

• Maeda Takuya

  Department of Agricultural Chemistry, University of Osaka Prefecture

• Kourai Hiroki

  Department of Applied Chemistry, Technical College of Tokushima University

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