In vivo Effect of Parathyroid Hormone and/or Calcitonin on the Lysosomal Enzyme Activity of Rat Bone
スポンサーリンク
概要
- 論文の詳細を見る
The effect of parathyroid hormone (PTH) and/or calcitonin <I>in vivo</I> on the lysosomal enzyme activity of rat bone was studied. PTH caused a significant increase in the acidphosphatase and β-glucuronidase activity of the rat tibia in a dose-related manner. Calcitonin also caused a significant increase in the acid-phosphatase of the tibia. Administration of calcitonin did not counteract the PTH-induced increase in the enzyme activity. These results may give rise to some doubt on the hypothesis that lysosomal enzymes play a vital role in the process of bone resorption.
- 社団法人 日本内分泌学会の論文
著者
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ORIMO Hajime
Health Science University
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Ohata Masahiro
Department Of Internal Medicine Wakayama Medical College Kihoku Branch Hospital
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Orimo Hajime
Department Of Endocrinology Tokyo Metropolitan Geriatric Medical Center
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Orimo Hajime
Department Of Geriatrics Faculty Of Medicine University Of Tokyo
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Orimo Hajime
General Research Committee For Prevention Of Osteoporosis Ministry Of Health And Welfare Tokyo Metro
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Fujita Takuo
Department Of Internal Medicine Kobe University School Of Medicine
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FUJITA TAKUO
Department of Geriatrics, Faculty of Medicine University of Tokyo
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FUJITA TAKUO
Department of Anatomy, Jikei University School of Medicine
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OHATA MASAHIRO
Department of Geriatrics University of Tokyo Faculty of Medicine
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ORIMO HAJIME
Department of Endocrinology and Metabolism, Tokyo Metropolitan Geriatric Hospital
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