Pyrophosphate Enhancement of Hypocalcemic Effect of Thyrocalcitonin in Rat
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概要
- 論文の詳細を見る
Enhancing effect of neutral phosphate on the hypocalcemic response to thyrocalcitonin (TC) has been previously demonstrated in rats. The possibility of <I>in vivo</I> pyrophosphate enhancement of TC effect was investigated in the present study. Marked dose-dependent hypocalcemia was found 60 min. after s.c. injection of graded doses of pyrophosphate (4-1, 024μmols) in both intact and thyroparathyroidectomized rats. At all dose levels of TC used simultaneously injected pyrophosphate markedly enhanced the 60 min, hypocalcemic response to graded doses of TC.
- 社団法人 日本内分泌学会の論文
著者
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Fujita Takuo
Department of Internal Medicine, Kobe University School of Medicine
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Yoshikawa Masaki
Department Of Cardiology Tsuyama Center Hospital
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Orimo Hajime
Department Of Endocrinology Tokyo Metropolitan Geriatric Medical Center
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Fujita Takuo
Department Of Internal Medicine Kobe University School Of Medicine
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