Ethnic difference in contribution of alleles of the interleukin-1 receptor antagonist gene to predisposition to osteoporosis
スポンサーリンク
概要
- 論文の詳細を見る
- 2002-06-01
著者
-
HOSOI Takayuki
Department of Advanced Medicine, National Center for Geriatrics and Gerontology
-
Emi Mitsuru
Department of Molecular Biology, Institute of Gerontology, Nippon Medical School
-
Inoue Satoshi
Department of Geriatric Medicine, University of Tokyo
-
OUCHI Yasuyoshi
Department of Geriatric Medicine, University of Tokyo
-
Emi Mitsuru
東京都老人医療センター
-
Emi Mitsuru
山形大学 医学部循環･呼吸･腎臓内科学
-
OGAWA Sumito
Department of Geriatric Medicine, Graduate School of Medicine, University of Tokyo
-
SHIRAKI Masataka
Research Institute and Practice for Involutional Diseases
-
Ogawa Sumito
東京大学 医学系研究科老年病学
-
Ogawa Sumito
Department Of Geriatric Medicine Graduate School Of Medicine The University Of Tokyo
-
Inoue S
Department Of Geriatric Medicine The University Of Tokyo
-
Inoue Satoshi
Department Of Geriatric Medicine The University Of Tokyo
-
Hosoi Takayuki
Tokyo Metropolitan Geriatric Hospital
-
Hosoi Takayuki
Endocrinology Section
-
Emi Mitsuru
Department Of Biochemistry Cancer Institute
-
ORIMO HAJIME
Tokyo Metropolitan Geriatric Medical Centre
-
Sugiyama Hiroaki
Department of Cardiology, the Cardiovascular Institute Hospital
-
ORIMO Hajime
Health Science University
-
Ouchi Yasuyoshi
Department Of Geriatric Medicine Faculty Of Medicine The University Of Tokyo
-
Orimo Hajime
Tokyo Metropolitan Geriatric Hospital
-
Emi Mitsuru
Department Of Neurology Hematology Metabolism Endocrinology And Diabetes Yamagata University School
-
Shintani Masafumi
Department Of Obstetrics And Gynecology Narakenritsu Mimuro Hospital
-
Hosoi Takayuki
Department Of Internal Medicine Tokyo Metropolitan Geriatric Hospital
-
Orimo Hajime
Department Of Geriatrics Faculty Of Medicine University Of Tokyo
-
Orimo Hajime
General Research Committee For Prevention Of Osteoporosis Ministry Of Health And Welfare Tokyo Metro
-
Emi Mitsuru
Department Of Neurology Hematology Metabolism Endocrinology And Diabetes Yamagata University School
-
Emi Mitsuru
Ddepartment Of Molecular Biology Institute Of Gerontology Nippon Medical School
-
Shiraki Masataka
Department Of Internal Medicine Research Institute And Practice For Involutional Diseases
-
Shiraki Masataka
Research Institute And Practice For Involutional Disease
-
Inoue Satoshi
Department Of Chemistry And Materials Engineering Faculty Of Chemistry Materials And Bioengineering
-
Emi Mitsuru
Department Of Neurology Hematology Metabolism Endocrinology And Diabetes Yamagata University School
-
Ouchi Yasuyoshi
Department Of Biostatistics Epidemiology And Preventive Health Sciences University Of Tokyo
-
Ouchi Yasuyoshi
Department Of Biostatistics Epidemiology And Preventive Health Sciences The University Of Tokyo
-
Sugiyama Hiroaki
Department Of Geriatric Medicine Graduate School Of Medicine The University Of Tokyo
-
OGAWA Sumito
Department of Geriatric Medicine, Graduate School of Medicine, The University of Tokyo
-
Inoue Satoshi
Department of Applied Chemistry, Graduate School of Engineering, Osaka University
関連論文
- Smoking Confers a MTHFR 677C>T Genotype-Dependent Risk for Systemic Atherosclerosis : Results from a Large Number of Elderly Autopsy Cases that Died in a Community-Based General Geriatric Hospital
- Overrepresentation of the EBAG9 Gene at 8q23 Associated with Early-Stage Breast Cancers
- Down-regulation of members of glycolipid-enriched membrane raft gene family, MAL and BENE, in cervical squamous cell cancers
- Genetic Association of Low-Density Lipoprotein Receptor-Related Protein 2 (LRP2) with Plasma Lipid Levels
- Association of nucleotide variations in the apolipoprotein B48 receptor gene (APOB48R) with hypercholesterolemia
- Hypercholesterolemia associated with splice-junction variation of inter-α-trypsin inhibitor heavy chain 4 (ITIH4) gene
- A promoter SNP (-1323T>C) in G-substrate gene (GSBS) correlates with hypercholesterolemia
- Hypertriglyceridemia associated with amino acid variation Asn985Tyr of the RP1 gene
- G-substrate gene promoter SNP (-1323T>C) modifies plasma total cholesterol and triglyceride phenotype in familial hypercholesterolemia : Intra-familial association study in an eight-generation hyperlipidemic kindred
- Soluble epoxide hydrolase variant (Glu287Arg) modifies plasma total cholesterol and triglyceride phenotype in familial hypercholesterolemia : intrafamilial association study in an eight-generation hyperlipidemic kindred
- Interaction between the LDL-receptor gene bearing a novel mutation and a variant in the apolipoprotein A-II promoter : molecular study in a 1135-member familial hypercholesterolemia kindred
- Characterization of liver-cirrhosis nodules by analysis of gene-expression profiles and patterns of allelic loss
- Common null variant, Arg192Stop, in a G-protein coupled receptor, olfactory receptor 1B1, associated with decreased serum cholinesterase activity
- Nutritional Effects of γ-Glutamyl Carboxylase Gene Polymorphism on the Correlation between the Vitamin K Status and γ-Carboxylation of Osteocalcin in Young Males
- Three Distinct Commonly Deleted Regions of Chromosome Arm 16q in Human Primary and Metastatic Prostate Cancers
- Localization of a Tumor Suppressor Gene Associated With Progression of Human Prostate Cancer Within a 1.2 Mb Region of 8p22-p21.3
- A 3-Mb Physical Map of the Chromosome Region 8p21.3-p22,Including a 600-kb Region Commonly Deleted in Human Hepatocellular Carcinoma, Colorectal Cancer, and Non-Small Cell Lung Cancer
- Clinical variant of Tangier disease in Japan : mutation of the ABCA1 gene in hypoalphalipoproteinemia with corneal lipidosis
- Allelic Losses of Loci at 3p25.1,8p22,13q12,17p13.3,and 22q13 Correlate with Postoperative Recurrence in Breast Cancer
- Segmental Copy Number Loss of SFMBT1 Gene in Elderly Individuals with Ventriculomegaly: A Community-Based Study
- Genetic mapping of allelic loss on chromosome 6q within heterogeneous prostate carcinoma
- Identification of a 1-Mb Common Region at 16q24.1-24.2 Deleted in Hepatocellular Carcinoma
- Allelic Loss at 1p34,13q12,17p13.3,and 17q21.1 Correlates With Poor Postoperative Prognosis in Breast Cancer
- Identification of a 1-cM Region of Common Deletion on 4q35 Associated With Progression of Hepatocellular Carcinoma
- Correlation of Allelic Loss with Poor Postoperative Survival in Breast Cancer
- PTEN/MMAC1 Mutations in Hepatocellular Carcinomas: Somatic Inactivation of Both Alleles in Tumors
- Frequent Allelic Loss at 6q26-27 in Breast Carcinomas of the Solid-tubular Histologic Type
- Detailed Deletion Mapping of Chromosome Arm 3p in Breast Cancers : A 2-cM Region on 3p 14.3-21.1 and a 5-cM Region on 3p 24.3-25.1 Commonly Deleted in Tumors
- Correlation of Allelic Losses and Clinicopathological Factors in Primary Breast Cancers
- Mapping of a Breast Cancer Tumor Suppressor Gene Locus to a 4-cM Interval on Chromosome 18q21
- Expression profiling to predict postoperative prognosis for estrogen receptor-negative breast cancers by analysis of 25,344 genes on a cDNA microarray
- Up-regulation of transcriptional factor E2F1 in papillary and anaplastic thyroid cancers
- Amplification, up-regulation and over-expression of C3G (CRK SH3 domain-binding guanine nucleotide-releasing factor) in non-small cell lung cancers
- Upregulation and Overexpression of Human X-box Binding Protein 1 (hXBP-1) Gene in Primary Breast Cancers
- Amplification, up-regulation and over-expression of DVL-1, the human counterpart of the Drosophila disheveled gene, in primary breast cancers
- Ret/PTC3 is the most frequent form of gene rearrangement in papillary thyroid carcinomas in Japan
- Allelic Loss on Chromosome 9q Is Associated with Lymph Node Metastasis of Primary Breast Cancer
- Nucleotide variations in genes encoding plasminogen activator inhibitor-2 and serine proteinase inhibitor B10 associated with prostate cancer
- Association of common missense changes in ELAC2 (HPC2) with prostate cancer in a Japanese case-control series
- Nucleotide variations in genes encoding carbonic anhydrase 8 and 10 associated with femoral bone mineral density in Japanese female with osteoporosis
- Association of genetic variations of genes encoding thrombospondin, type 1, domain-containing 4 and 7A with low bone mineral density in Japanese women with osteoporosis
- Genomic Structure and Mapping of Human Orphan Receptor LXR Alpha : Upregulation of LXRa mRNA During Monocyte to Macrophage Differentiation
- Genetic Association between Aldehyde Dehydrogenase 2 (ALDH2) Variation and High-Density Lipoprotein Cholesterol (HDL-C) Among Non-Drinkers in Two Large Population Samples in Japan
- Association of an intronic haplotype of the LIPC gene with hyperalphalipoproteinemia in two independent populations
- Functional impairment of two novel mutations detected in lipoprotein-associated phospholipase A2 (Lp-PLA2) deficiency patients
- Correlation of Allelic Losses and Clinicopathological Factors in 504 Primary Breast Cancers
- Association of Allelic Losses at 3p25.1, 13q12, or 17p13.3 with Poor Prognosis in Breast Cancers with Lymph Node Metastasis
- Allelic Loss at 1p34-36 Predicts Poor Prognosis in Node-negative Breast Cancer
- DNA alterations during multi-step development of human hepatocellular carcinomas revealed by laser capture microdissection
- Genomic structure of the gene encoding human 3-hydroxy-3-methyl-glutaryl coenzyme A reductase : comparison of exon/intron organization of sterol-sensing domains among four related genes
- Genomic structure and chromosomal mapping of the human sterol regulatory element binding protein (SREBP) cleavage-activating protein (SCAP) gene
- Differentially Regulated Genes as Putative Targets of Amplifications at 20q in Ovarian Cancers
- Definition of a 1-Mb homozygous deletion at 9q32-q33 in a human bladder-cancer cell line
- Two Target Regions of Allelic Loss on Chromosome 9 in Urinary-bladder Cancer
- Mapping of a New Target Region of Allelic Loss to a 6-cM Interval at 21q21 in Primary Breast Cancers
- Polymorphism of cytochrome P450 2B6 and prostate cancer risk : A significant association in a Japanese population
- Role of DNA repair systems in malignant tumor development in the elderly
- Reviewing the definition of "elderly"
- Impaired gamma carboxylation of osteocalcin in elderly women with type II diabetes mellitus : relationship between increase in undercarboxylated osteocalcin levels and low bone mineral density
- Association of a single nucleotide polymorphism in the secreted frizzled-related protein 4 (sFRP4) gene with bone mineral density
- Hypermethylation associated with inactivation of the SOCS-1 gene, a JAK/STAT inhibitor, in human hepatoblastomas
- Molecular cloning, tissue expression, and chromosomal assignment of a novel gene encoding a subunit of the human signal-recognition particle
- Association of single nucleotide polymorphisms in the promoter region of the pro-opiomelanocortin gene (POMC) with low bone mineral density in adult women
- Association of a single-nucleotide polymorphism in the promoter region of leukemia inhibitory factor receptor gene with low bone mineral density in adult women
- Linkage disequilibrium and haplotype analysis among four novel single-nucleotide polymorphisms in the human leukemia inhibitory factor (LIF) gene
- Association of a single-nucleotide polymorphism in low-density lipoprotein receptor-related protein 5 gene with bone mineral density
- Association of genetic variation of the RIL gene, encoding a PDZ-LIM domain protein and localized in 5q31.1, with low bone mineral density in adult Japanese women
- Association of natural tooth loss with genetic variation at the human matrix Gla protein locus in elderly women
- Association of the -381T/C promoter variation of the brain natriuretic peptide gene with low bone-mineral density and rapid postmenopausal bone loss
- Thirteen single-nucleotide polymorphisms in the human osteopontin gene identified by sequencing of the entire gene in Japanese individuals
- Linkage disequilibrium and haplotype analysis among ten single-nucleotide polymorphisms of interleukin 11 identified by sequencing of the gene
- Genomic structure and chromosomal mapping of the human Site-1 protease (S1P) gene
- Isolation and radiation hybrid mapping of a highly polymorphic CA repeat sequence at the SREBP cleavage-activating protein (SCAP) locus
- The sample size required for intervention studies on fracture prevention can be decreased by using a bone resorption marker in the inclusion criteria : prospective study of a subset of the Nagano Cohort, on behalf of the Adequate Treatment of Osteoporosis
- Absolute height reduction and percent height ratio of the vertebral body in incident fracture in Japanese women
- A nucleotide variant in the promoter region of the interleukin-6 gene associated with decreased bone mineral density
- Diagnostic criteria for primary osteoporosis: year 2000 revision
- Association of bone mineral density with a dinucleotide repeat polymorphism at the calcitonin (CT) locus
- Linkage of interleukin 6 locus to human osteopenia by sibling pair analysis
- Association of bone mineral density with polymorphism of the human matrix Gla protein locus in elderly women
- Identification of a novel polymorphism of estrogen receptor-α gene that is associated with calcium excretion in urine
- Trends in the incidence of hip fracture in Japan,1987-1997:The third nationwide survey
- Guidelines on the use of biochemical markers of bone turnover in osteoporosis (2001)
- Association of estrogen receptor β (ESR2) gene polymorphism with blood pressure
- Nationwide incidence survey of femoral neck fracture in Japan, 1992
- Case of bone Paget's disease with cheek pain, hearing loss and tremor whose histological findings showed peculiar calcified structures
- The Val158Met polymorphism of the catechol-O-methyltransferase gene is not associated with the risk of sporadic or latent prostate cancer in Japanese men
- Association of HTRA1 promoter polymorphism with spinal disc degeneration in Japanese women
- Cooperative effect of serum 25-hydroxyvitamin D concentration and a polymorphism of transforming growth factor-β1 gene on the prevalence of vertebral fractures in postmenopausal osteoporosis
- Association of a Single Nucleotide Polymorphism in the Insulin-Like Growth Factor-1 Receptor Gene With Spinal Disc Degeneration in Postmenopausal Japanese Women
- Association of radial bone mineral density with CA repeat polymorphism at the interleukin 6 locus in postmenoposal Japanese women
- High level of serum undercarboxylated osteocalcin in patients with incident fractures during bisphosphonate treatment
- Postprandial Reactive Hypoglycemia in an Oldest-old Patient Effectively Treated with Low-dose Acarbose
- A Case of Type 2 Diabetes Mellitus in an Elderly Patient with Rapid Attenuation of Insulin Secretion that Resembled Fulminant Type 1 DM but with Incomplete Beta Cell Damage
- Association of amino acid variation (Trp64Arg) in the beta3-adrenergic receptor gene with bone mineral density
- Ethnic difference in contribution of alleles of the interleukin-1 receptor antagonist gene to predisposition to osteoporosis
- Association between a promoter polymorphism of the paraoxonase PON1 gene and pathologically verified idiopathic Parkinson's disease
- Isolation and radiation hybrid mapping of dinucleotide repeat polymorphism at the human estrogen receptor βlocus
- ASSOCIATION OF ESTROGEN RECEPTOR DINUCLEOTIDE REPEAT POLYMORPHISM WITH OSTEOPOROSIS
- Design of a pragmatic approach to evaluate the effectiveness of concurrent treatment for the prevention of osteoporotic fractures