Failure of Estradiol Benzoate Given after Birth to Prevent the Adrenal Glands from Shrinking in Newborn Rats
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概要
- 論文の詳細を見る
Two hr after birth, newborn rats were given a subcutaneous injection of 0.01mg estradiol benzoate dissolved in 0.05ml sesame oil. Other siblings were given sesame oil alone. Autopsy was performed on days 1, 2 and 3 after birth. Gravimetric and histologic examinations of the adrenals from these animals and from normal littermate controls were made together with the determination of plasma corticosterone concentrations. In all the three groups of rats, estrogen-treated, oil-treated and nontreated, the weight of the adrenal glands declined with a concomitant decrease in the plasma corticosterone concentrations. The results indicate that estradiol benzoate, when given after birth, does not prevent the neonatal adrenal from shrinking.
- 社団法人 日本内分泌学会の論文
著者
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HASHIMOTO Yoshiyuki
Department of Hygienic Chemistry, Pharmaceutical Institute, Tohoku University
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Arishima Kazuyoshi
Department Of Anatomy Ii Azabu University School Of Veterinary Medicine
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Eguchi Yasunobu
Department Of Anatomy Ii Azabu University School Of Veterinary Medicine
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Morikawa Yoshio
Department Of Integrated Structural Biosciences Division Of Veterinary Science Graduate School Of Li
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Hashimoto Yoshiyuki
Department Of Hygienic Chemistry Faculty Of Pharmaceutical Sciences Tohoku University
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ARISHIMA Kazuyoshi
Department of Anatomy II
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ARISHIMA KAZUYOSHI
Department of Veterinary Anatomy, College of Agriculture, University of Osaka Prefecture
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MORIKAWA Yoshio
Department of Veterinary Anatomy, College of Agriculture, University of Osaka Prefecture
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