INCREASE OF β-GLUCURONIDASE ACTIVITY IN THE SERUM OF RATS ADMINISTERED ORGANOPHONPHATE AND CARBAMATE INSECTICIDES.
スポンサーリンク
概要
- 論文の詳細を見る
An approximately 50-fold increase in serum β-glucuronidase activity appeared 2 hours after the administration of such organophosphate insecticides as dichlorvs, diazinon and disulfoton and of a carbamate insecticide, carbaryl. The activities of other acid hydrolases in the serum such as ribonuclease, acid phosphatase, hyaluronidase and N-acetylglucosaminidase did not change significantly after the insecticide treatment. The response was related to the dose level and was evident after a single intraperitoneal dose of diazinon as low as 1.6 mg/kg. This appearence of an increase in β-glucuronidase was retarded by pretreatment with SKF 525A, an inhibitor of drug metabolizing enzyme. When β-glucuronidase was elevated by a large dose of diazinon, full response to a second dose of diazinon did not occur until approximately one month after administration of the first dose.
- 日本トキシコロジー学会の論文
- 1981-02-25
著者
-
SUZUKI Yasuo
Department of Biochemistry, University of Shizuoka, School of Pharmaceutical Sciences, Core Research
-
HASHIMOTO Yoshiyuki
Department of Hygienic Chemistry, Pharmaceutical Institute, Tohoku University
-
Kikuchi Hideaki
Department Of Hygienic Chemistry Pharmaceutical Institute Tohoku University
-
Suzuki Yasuo
Department Of Applied Physics Faculty Of Engineering Fukui University
-
Hashimoto Yoshiyuki
Department Of Hygienic Chemistry Faculty Of Pharmaceutical Sciences Tohoku University
-
Suzuki Yasuo
Department Of Hygienic Chemistry Pharmaceutical Institute Tohoku University
-
HASHIMOTO Yoshiyuki
Department of Hygienic Chemistry, Pharmaceutical Institute Tohoku University
-
Kikuchi Hideaki
Department of Biochemistry and Molecular Biology, Faculty of Agriculture and Life Science, Hirosaki University
関連論文
- Identification and Characterization of Carbohydrate Molecules in Mammalian Cells Recognized by Dengue Virus Type 2
- A Unique Phosphatidylinositol Bearing a Novel Branched-Chain Fatty Acid from Rhodococcus equi Binds to Influenza Virus Hemagglutinin and Inhibits the Infection of Cells
- lnhibitory action of sulfatide a putative ligand for L-selectiv on B cell proliferation and lg prodrction
- The New Role of Disodium Cromoglycate in the Treatment of Adults with Bronchial Asthma
- In Vitro Inhibition of Human Influenza A Virus Infection by Fruit-Juice Concentrate of Japanese Plum (Prunus mume SIEB. et ZUCC)(Microbiology)
- Suppression of the Biosynthesis of Cellular Sphingolipids Results in the Inhibition of the Maturation of Influenza Virus Particles in MDCK Cells(Highlighted paper selected by Editor-in-chief,Biochemistry)
- In Vitro and in Vivo Inhibitory Effects of Disodium Cromoglycate on Influenza Virus Infection(Pharmacology)
- Duck and Human Pandemic Influenza A Viruses Retain Sialidase Activity under Low pH Conditions^1
- A Macrocyclic Sialic Acid Cluster as a Host, as an Adsorbate, and as a Ligand for Lectin and Virus
- Ganglioside GM_ on the Cell Surface Is Involved in the Infection by Human Rotavirus KUN and MO Strains
- ROLE OF ICAM-1 AND LFA-1 IN ENDOTOXIN-INDUCED UVEITIS IN MICE
- Correlation of the Mixing Process and the Power Consumption of Double-Blade Kneaders
- Power Consumption of Double-Bladed Kneaders of Various Shapes
- Synthetic Studies on Selection Ligands/Inhibitors. Synthesis and Biological Evaluation of Sulfated and Phosphorylated β-D-Galacto- and Lactopyranosides Containing Fatty-Alkyl Residues of Different Carbon Chain Lengths
- SYNTHESIS AND BIOLOGICAL ACTIVITY OF THE NOVEL SULFATED AND PHOSPHORYLATED BIVALENT β-D-GALACTOPYRANOSIDES CONTAINING FATTY-ALKYL RESIDUES
- Influenza A Virus-Binding Activity of Glycoglycerolipids of Aquatic Bacteria
- Effects of an Eyeglass-free 3-D Display on the Human Visual System
- Low Susceptibility of Long-Evans Cinnamon Rats to N-Butyl-N-(4-hydroxybutyl)-nitrosamine-induced Urinary Bladder Carcinogenesis and Inhibitory Effect of Urinary Copper
- Effects of D-Galactosamine Hydrochloride and Partial Hepatectomy on Spontaneous Hepatic Injury and Hepatocarcinogenesis in Long-Evans Cinnamon Rats
- Sulfatide and Its Synthetic Analogues Recognition by Moraxella catarrhalis
- β-Thujaplicin Zinc Chelate Induces Apoptosis in Mouse High Metastatic Melanoma B16BL6 Cells
- High-Frequency,High-Power Microwave Generation by a Vitual Cathode Oscillator
- Migrainous Cerebral Infarction Triggered by Alcohol Intake Under the Burning Sun
- Visual Field Defects Associated wit Sick Sinus Syndrome
- A Review of 244 Orbital Tumors in Japanese Patients During a 21-Year Period : Origins and Locations
- Leaky Neural Integration Observed in Square-wave Jerks
- Effect of High-dose Intravenous Steroid Pulse Therapy Followed by 3-Month Oral Steroid Therapy for Graves' Ophthalmopathy
- Retroperitoneal mucinous cystadenoma : Report of two cases and review of the literature
- Synthesis of High Refractive Index Poly(thioether sulfone)s with High Abbe's Number Derived from 2,5-Bis(sulfanylmethyl)-1,4-dithiane
- Role of Sialylglycoconjugate(s) in the Initial Phase of Metastasis of Liver-metastatic RAW117 Lymphoma Cells
- Characterization and In Vitro Cytotoxic Effect of Adriamycin-conjugated Monoclonal Antibody Prepared Against Breast Cancer Cell Line
- Characterization of A New Breast Cancer-Associated Antigen and Its Relationship to MUC1 and TAG-72 Antigens
- A case of recurrent invasive lobular carcinoma of the breast found as metastasis to the duodenum
- Gross Total Removal of Gliomas in the Pulvinar and Correlative Microsurgical Anatomy
- Anti-Mouse Sperm Monoclonal Antibody, A-1,Inhibits Sperm Capacitation, Acrosome Reaction and Calcium Influx into Spermatocytes
- Status of Currently Circulating Dengue Virus Responsible for the Epidemic in Bangladesh in the Year 2002
- Power Consumption Diagram for Wet Particle Kneader Mixers - In the Case that Rheological Properties for Wet Particles cannot be Measured -
- Synthesis of Highly Refractive and Transparent Polyimides Derived from 4,4'[p-Sulfonylbis(phenylenesulfanyl)]diphthalic Anhydride and Various Sulfur-containing Aromatic Diamines
- Regio-controlled Oxidative Polymerization of 2,5-Dimethylphenol by Using CuCl-TMEDA Complex
- Generation and Focusing of Intense Ion Beams with an Inverse Pinch Ion Diode
- Ion Beam Generation and its Applications with "HARIMA-II"
- Ion Beam Generation with the "Inverse Pinch Ion Diode"
- Retrieval of a Migrated Detachable Coil : Case Report
- Magnetic Resonance Imaging and Histology of a Large Cystic Meningioma : Case Report
- Mechanically Detachable Coil Embolization of a Traumatic Carotid-Cavernous Fistula : Case Report
- SUSCEPTIBILITY OF ANIMALS TO HEPATOCARCINOGENIC AROMATIC AMINES CORRELATES WITH THE INDUCTION OF THE CARCINOGEN ACTIVATION ENZYME (S) WITH THE AMINES
- Plasma Linear Accelerator II
- Plasma Acceleration by the Radiation Pressure
- Ultrasonic Absorption of n-BuOH-Water System with Hypercritical Point
- Dynamical Scaling for Sound Propagation in Critical Binary Mixture
- Binding of influenza type A viruses to group B Streptococcus and haemagglutination by virus-bound bacteria
- Role of Atp7b Gene in Spontaneous and N-Diethylnitrosamine-induced Carcinogenesis in a New Congenic Strain, WKAH.C-Atp7b Rats
- Infectivity and Arthritis Induction of Borrelia japonica on SCID Mice and Immune Competent Mice: Possible Role of Galactosylceramide Binding Activity on Initiation of Infection
- Inactivation of Human Type A and B Influenza Viruses by Tea-Seed Saponins
- Intracellular Localization of UDP-Glucuronosyltransferase Expressed from the Transfected cDNA in Cultured Cells
- Plasma Linear Accelerator I
- Convergence eye movements evoked by microstimulation of the rostral superior colliculus in the cat
- Branch Retinal Artery Occlusion Associated with Rupture of Retinal Arteriolar Macroaneurysm on the Optic Disc
- Transition from Upbeat to Downbeat Nystagmus Observed in a Patient with Wernicke's Encephalopathy
- MRI Findings of Giant Plasmacytoma of the Calvarium
- Detection of Chlorophyll Breakdown Products in the Senescent Leaves of Higher Plants
- Binding of influenza and paramyxoviruses to Group B Streptococcus with the terminal sialyl-galactose linkage
- Adaptive changes in human smooth pursuit eye movement
- Accurate Estimation of the Number of Weak Coherent Signals
- Extraneural Metastasis of High Grade Glioma Without Simultaneous Central Nervous System Recurrence : Case Report
- Fine structure and elemental component of blackish-brown deposits on the enamel surfaces of deciduous teeth in children
- Identification of a Major PAF Acetylhydrolase in Human Serum/Plasma as a 43 kDa Glycoprotein Containing About 9kDa Asparagine-Conjugated Sugar Chain(s)^1
- Effects of Chemical Solutions on the Toughness of Polypropylene
- ALTERATION OF HEPATIC CYTOCHROME P-450 ISOZYMES DURING HEPATOCARCINOGENESIS PROCESS IN RATS
- Altered Expression of Hepatic CYP1A Enzymes in Rat Hepatocarcinogenesis
- VALIDITY OF ACTIVITY INDICES IN ULCERATIVE COLITIS : COMPARISON OF CLINICAL AND ENDOSCOPIC INDICES
- Stability of an Intense Pulsed Ion Beam during Successive Operation
- Effect of Adsorbed Matter on Intense Pulsed Ion Beam Generation
- Incomplete Oculomotor Palsy with Pupil Sparing Caused by Compression of the Oculomotor Nerve by a Posterior Communicationg Posterior Cerebral Aneurysm
- Reversible Horner's Syndrome and Dysthyroid Ocular Myopathy Associated with Hashimoto's Disease
- The Relationship between Adherence and Liver Metastatic Ability in Murine Mastocytoma Cell Line
- Alignment by Poling and Regioselective Photodimerization of Stilbazolium Ions Dispersed in Polyelectrolytes
- INCREASE OF β-GLUCURONIDASE ACTIVITY IN THE SERUM OF RATS ADMINISTERED ORGANOPHONPHATE AND CARBAMATE INSECTICIDES.
- Sulfatide, a Specific Sugar Ligand for L-Selectin, Blocks CCl_4-induced Liver Inflammation in Rats
- Failure of Estradiol Benzoate Given after Birth to Prevent the Adrenal Glands from Shrinking in Newborn Rats
- Perinatal Changes in the Liver Weight with Observations of Effects of Fetal Adrenalectomy and Fetal Decapitation with or without Maternal Adrenalectomy in the Rat
- Hormonal Control of Liver Glycogen in Fetal and Newborn Rats
- Histological Development of the Testis of the Mouse during Embryonic Stages
- Resets of torsional eye position errors in different lighting conditions
- Histological Studies on the Developing Femur of the Male Mouse
- Clinical trial : effects of an oral preparation of mesalazine at 4 g/day on moderately active ulcerative colitis. A phase III parallel-dosing study
- Influence of long-term low-dose methotrexate therapy on periarticular and generalized osteoporosis in rheumatoid arthritis
- Thrombotic microangiopathic hemolytic anemia in systemic lupus erythematosus associated with antiphospholipid antibodies: usefulness of monitoring coagulation-fibrinolysis markers
- 高病原性トリインフルエンザウイルスとそのシアロ糖鎖レセプター
- Value of serum IgG4 in the diagnosis of IgG4-related disease and in differentiation from rheumatic diseases and other diseases
- Sialobiology of Influenza : Molecular Mechanism of Host Range Variation of Influenza Viruses
- Nonstoichiometry and electrical resistivity in two mixed metal oxides, La2NiO4-x and LaSrNiO4-x.
- タイトル無し
- Turner's Syndrome Associated with Hashimoto's Thyroiditis and Sarcoidosis: A Case Report.
- タイトル無し
- タイトル無し
- タイトル無し
- Effect of Gamma Radiation on Silica Gel
- Syntheses and crystal and molecular structure of (hexaaquabis(2-naphthalenesulfonato)lanthanoid(III)) 2-naphthalenesulfonate trihydrate, (Ln(C10H7SO3)2(H2O)6)(C10H7SO3)3H2O(Ln=Pr, Nd, Sm, Eu, Gd, Dy, Er, and Yb).
- タイトル無し