Effect of anti-inflammatory agents on the release of acid phosphatase in the epidermis following ultraviolet light exposure.
スポンサーリンク
概要
- 論文の詳細を見る
Ultraviolet (UV) exposure of a homogenate of guinea pig epidermis resulted in the release of acid hydrolases from the 20, 000×g pellet fraction into the medium. Release of enzymes such as acid phosphatase, acid DNase, β-glucuronidase was dependent on the radiant energy of UV light. These enzymes could be released or inactivated by varying the dose of UV energy. Both the biochemical facts and the electron microscopic examination suggested that the 20, 000×g pellet associated with lysosome-rich fraction. The in vitro incubation of homogenates or 20, 000×g pellet with steriodal and non-steriodal anti-inflammatory agents prior to UV exposure significantly reduced the relase of acid phosphatase. Fluocinonide, betamethasone and fluocinonide acetonide were all found to be effective: however, the latter was the least active. Indomethacin was not as effective as the more active corticosteroids.
- 久留米大学医学部 The Kurume Medical Journal 編集部の論文
著者
-
Kinoshita Akira
Department Of Applied Science Faculty Of Engineering Tokyo Electrical Engineering College
-
SHIMADA TATSUO
Second Department of Anatomy, Kurume University School of Medicine
-
KINOSHITA AKIRA
Department of Medical Biochemistry, Kurume University School of Medicine
-
OGURA RYOHEI
Department of Biochemistry, Kurume University School of Medicine
-
MURAKAMI MASAHIRO
Second Department of Anatomy, Kurume University School of Medicine
-
KNOX JOHN
Department of Dermatology, Baylor College of Medicine
関連論文
- PAX9 and TGFB3 are linked to susceptibility to nonsyndromic cleft lip with or without cleft palate in the Japanese : population-based and family-based candidate gene analyses
- The IHPK1 gene is disrupted at the 3p21. 31 breakpoint of t(3 ; 9) in a family with type 2 diabetes mellitus
- A catalog of 106 single-nucleotide polymorphisms (SNPs) and 11 other types of variations in genes for transforming growth factor-β1 (TGF-β1) and its signaling pathway
- A Japanese patient with a mild Lenz-Majewski syndrome
- Specific serum antibodies against membranous proteins of a human immortal chondrocytic cell line (HCS-2/8) in rheumatoid arthritis and their relationship to the natural history of this disease
- 128. Retinal Hemorrhage in Acute Head Injury
- RAPD法を用いたShorea属3種における遺伝的変異量の推定〔英文〕
- Mechanism of the Contracting Actions of K, Acetylcholine, Histamine, Noradrenaline and Ba in the Excised Vas Deferens of Guinea Pig, Particularly in Relation to Ca
- Subarachnoid Hemorrhage Associated With von Willebrand's Disease : Case Report
- Absorption and Reflection of Vapor Grown Single Crystal Platelets of β-Ga_2O_3
- Refractive Index of β-Ga_2O_3
- Photo-Sensitive Characteristics of Ag_2S Thin Film
- Mutations in PRRT2 responsible for paroxysmal kinesigenic dyskinesias also cause benign familial infantile convulsions
- Epidemiology of human papillomavirus genotypes in pregnant Japanese women
- Clinical application of fetal sex determination using cell-free fetal DNA in pregnant carriers of X-linked genetic disorders
- Novel mutations in the SIL1 gene in a Japanese pedigree with the Marinesco-Sjogren syndrome
- A type of familial cleft of the soft palate maps to 2p24.2–p24.1 or 2p21–p12
- Molecular karyotyping in 17 patients and mutation screening in 41 patients with Kabuki syndrome
- Medical Thoracoscopy Performed Under Local Anesthesia Is Useful for Diagnosing Pleural Metastasis of Renal Cell Carcinoma
- Effect of monochromatic ultraviolet light on lipoperoxide formation and on the function of isolated rat liver mitochondria.
- STRUCTURAL CHANGES OF THE RAT CHOROID PLEXUS FOLLOWING INTRAVENTRICULAR INJECTION OF SOME DRUGS:TRANSMISSION AND SCANNING ELECTRON MICROSCOPIC OBSERVATION
- Effect of anti-inflammatory agents on the release of acid phosphatase in the epidermis following ultraviolet light exposure.
- Subcellular distribution of acid DNase of rat submandibular gland.
- Assay for flavins in rat heart mitochondria by high pressure liquid chromatography.
- Arachidonate Metabolism in Bovine Gallbladder Mucosa.
- Electron spin resonance studies on the spin label of rat cardiac mitochondria treated with adriamycin.
- UV Exposure alters the membrane lipid composition and cell membrane fluidity of intact cultured B-16 melanoma cells.
- Effects of ultraviolet irradiation on cultured B-16 melanoma cells - Membrane fluidity, lipid composition and phospholipase activity.:Membrane Fluidity, Lipid Composition and Phospholipase Activity
- Riboflavin Deficiency Caused by Treatment with Adriamycin.
- THE OXYGEN UPTAKE CAUSED BY THE CYSTEINE UTILIZATION OF RAT EPIDERMIS
- THE CYTOPLASMIC ANNULATE LAMELLAE IN THE PRINCIPAL CELLS OF THE EPIDIDYMAL EPITHELIUM OF THE JAPANESE MONKEY
- Biochemical and morphological changes in isolated rat liver mitochondria exposed to ultraviolet light.
- ESR Spin-labeling method of determining membrane fluidity in biological materials. Tissue culture cells, cardiac mtiochondria, erythrocytes and epidermal cells.:Tissue Culture Cells, Cardiac Mitochondria, Erythrocytes and Epidermal Cells
- THE POSSIBLE ROLE OF GLUTATHIONE TO LACTATE DEHYDROGENASE ACTIVITY IN THE EPIDERMIS
- Inhibitory action of water-extract of cow snout epidermis on mushroom tyrosinase.
- BIOCHEMICAL AND SCANNING ELECTRON MICROSCOPIC PROPERTIES OF MITOCHONDRIA ISOLATED FROM RAT CARDIAC MUSCLE
- Study of acid DNase in cow snout epidermis by micro slab electrophoresis using acidic and basic gel sheet.
- THE FUNDAMENTAL STUDY ON THE MECHANISM OF THE CALCULI FORMATION (I)
- Assay for lipid peroxide content in mitochondria by the thiobarbituric acid reaction.
- STUDIES ON THE DEPOSITION OF CALCIUM SALT
- BIOCHEMICAL CHANGES IN RAT EPIDERMIS INDUCED BY CHRONIC ULTRAVIOLET-LIGHT EXPOSURE
- Biochemical role of glutathione on the sulfhydryl disulfide interchange reaction with randomly cross-linked ribonuclease.
- INFLUENCE OF HAIR GROWTH CYCLE ON SULFHYDRYL GROUPS OF RAT EPIDERMIS
- A new simplified radioisotope method for determining hypoxanthine-guanine phosphoribosyltransferase and adenine phosphoribosyltransferase with the use of thin-layer radio-chromatogram scanner.
- Copy number variation of the antimicrobial-gene, defensin beta 4, is associated with susceptibility to cervical cancer