THE POSSIBLE ROLE OF GLUTATHIONE TO LACTATE DEHYDROGENASE ACTIVITY IN THE EPIDERMIS
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概要
- 論文の詳細を見る
The alternation of lactate dehydrogenase (LDH) activity in mouse epidermis following intraperitoneal administration of 100 mg glutathione (GSH) was observed. The intraperitoneal administration of GSH produced a temporary increase in the GSH level and LDH activity in the blood. The GSH level in the epidermis increased significantly at the 2nd through 3rd hour postadministration. The LDH activity in the epidermis increased about 2-fold at the 3rd hour. The increase of LDH activity in the epidermis was not observed after administration of 10 mg GSH.The incorporation of [<SUP>14</SUP>C] glycine into protein of the epidermis was not accelerated following intraperitoneal administration of GSH. The possible role of GSH to LDH in the epidermis was considered to be a continuous reactivation of LDH.
- 久留米大学医学部 The Kurume Medical Journal 編集部の論文
著者
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OGURA RYOHEI
Department of Biochemistry, Kurume University School of Medicine
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TAKASHIMA YUKIE
Department of Medical Biochemistry, Kurume University School of Medicine
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MARUTA TOSHIO
Department of Medical Biochemistry, Kurume University School of Medicine
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