Acid phosphatase activity in the hexadecane-induced hyperkeratosis of guinea pig epidermis.

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概要

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• Topical application of hexadecane to the skin of guinea pig resulted in a marked hyperkeratotic response of the treated skin. The acid hydrolases activity : acid phosphatase and acid DNase, of non-treated and hexadecanetreated epidermis was followed for one month post-application. The remarkable increase in acid phosphatase activity was found to parallel development of hyperkeratotis, and diminished as the desquamation was in progress. However, the reduction in the level of acid DNase was observed in the hyperkeratotic epidermis. The biological role and significance of acid hydrolases on the hyperkeratotic epidermis were discussed.

• 久留米大学医学部 The Kurume Medical Journal 編集部の論文

著者

• MARUTA TOSHIO

  Department of Medical Biochemistry, Kurume University School of Medicine

関連論文

• THE POSSIBLE ROLE OF GLUTATHIONE TO LACTATE DEHYDROGENASE ACTIVITY IN THE EPIDERMIS
• Acid phosphatase activity in the hexadecane-induced hyperkeratosis of guinea pig epidermis.

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