Biochemical role of glutathione on the sulfhydryl disulfide interchange reaction with randomly cross-linked ribonuclease.
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概要
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An enzyme which catalyzes sulfhydryl disulfide interchange in proteins containing incorrect disulfide bonds has been reported by several investigators. In the present paper, the biological significance of glutathione on the interchange reaction to the randomly cross-linked RNase was determined. It was suggested that glutathione must be also involved in the rearrangement of the incorrect disulfide bond to form the correct disulfide bond of the corresponding native protein.
- 久留米大学医学部 The Kurume Medical Journal 編集部の論文
著者
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NODA Kazuyoshi
Department of Applied Physics, The University of Tokyo
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OGURA Ryohei
Department of Medical Biochemistry, Kurume University School of Medicine
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OGURA RYOHEI
Department of Biochemistry, Kurume University School of Medicine
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NINOMIYA FUYUHIKO
Department of Medical Biochemistry, Kurume University School of Medicine
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