L-Methionine enhances the contractile response to norepinephrine of rat vas deferens.
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概要
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Under Ca-depleted conditions, the contractile responses of rat vas deferens in the presence of norepinephrine were not elicited until the addition of CaCl<SUB>2</SUB>. L-Methionine enhanced the contractile response of vas deferens in the presence of methylation blockers under these conditions. The enhancing effect of L-methionine on some other smooth muscles could not be determined because under Ca-depleted conditions, these muscles showed 60-80% of the maximal contractile response on addition of CaCl<SUB>2</SUB> alone. Theas findings suggested that L-methionine has an enhancing effect on contraction of the rat vas deferens as it does on rat uterine muscle.
著者
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Ichida Seiji
Department Of Biological Chemistry School Of Pharmaceutical Sciences Kinki University
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Yoshioka Kazuo
Department Of Pediatrics Kinki University School Of Medicine
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Ariyoshi Shunji
Department Of Pharmacology Saga Medical School
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Ichida Seiji
Department of Biological Chemistry, Faculty of Pharmacy, Kinki University
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OKA Hiroaki
Department of Biological Chemistry, Faculty of Pharmacy, Kinki University
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ODA Yasuo
Department of Biological Chemistry, Faculty of Pharmacy, Kinki University
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ARIYOSHI Shunji
Department of Biological Chemistry, Faculty of Pharmacy, Kinki University
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