Respiratory and Cardiovascular Reflexes Elicited by Nasal Instillation of Capsaicin to Anesthetized, Spontaneously Breathing Dogs.
スポンサーリンク
概要
- 論文の詳細を見る
Cardiopulmonary reflexes elicited by capsaicin (CAPS) instilled into the nasal passages were determined in 6 anesthetized dogs breathing spontaneously. Nasal instillation of CAPS (10 μg/m l, 10 ml) induced: 1) apneic response characterized by an increase in expiration time; 2) bronchoconstrictor response characterized by an increase in lung resistance and a decrease in dynamic compliance; and 3) cardiovascular response characterized by a decrease in heart rate and an increase in arterial blood pressure. These reflex responses to CAPS were attenuated by pretreatment with a higher dose of CAPS (100 μg/ml, 10 ml), suggesting desensitization of CAPS-sensitive endings. These results suggest that marked cardiopulmonary reflexes are produced by nasal CAPS instillation, which may result, at least in part, from stimulation of nasal CAPS-sensitive sensory afferents.
- 公益社団法人 日本獣医学会の論文
著者
-
MUTOH Tatsushi
Department of Surgical Neurology, Research Institute for Brain and Blood Vessels-Akita
-
Kuwahara Masayoshi
Department Of Comparative Pathophysiology Graduate School Of Agricultural And Life Science The Unive
-
Tsubone Hirokazu
Department Of Comparative Pathophysiology Graduate School Of Agricultural And Life Science The Unive
-
Sasaki Nobuo
Department Of Pharmacology Faculty Of Veterinary Medicine Hokkaido University
-
Kanamaru Arata
Department Of Physiology Showa University School Of Medicine
-
Tsubone Hirokazu
Department of Comparative Pathophysiology, Graduate School of Agricultural and Life Sciences, The University of Tokyo
-
NISHIMURA Ryohei
Department of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo
-
MUTOH Tatsushi
Department of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo
-
MUTOH Tatsushi
Department of Pediatic and Internal Medicine, School of Medicine, University of California, Davis, CA95616, U.S.A.
-
Sasaki Nobuo
Department of Biological Science and Technology, Tokyo University of Science
-
TSUBONE Hirokazu
Department Comparative Pathophysiology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan
-
KANAMARU Arata
Department of Comparative Pathophysiology, Graduate School of Agricultural and Life Sciences, The University of Tokyo
-
KANAMARU Arata
Department Comparative Pathophysiology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan
関連論文
- Impact of Early Surgical Evacuation of Sylvian Hematoma on Clinical Course and Outcome After Subarachnoid Hemorrhage
- Diurnal Fluctuations of Heart Rate, Body Temperature and Locomotor Activity in the House Musk Shrew (Suncus murinus)
- Connexin-43 Redistribution and Gap Junction Activation During Forced Restraint Protects Against Sudden Arrhythmic Death in Rats
- Anti-Tumor Effect of Adenoviral Vector-Mediated p53 Gene Transfer on the Growth of Canine Osteosarcoma Xenografts in Nude Mice
- Suppressive Effect of Cocoa Powder on Atherosclerosis in Kurosawa and Kusanagi-hypercholesterolemic Rabbits
- Availability of miniature pigs for the evaluation of cardiovascular system affected by drugs(Circulatory system, Proceedings of the 32nd Annual Meeting)
- The Difference in Citric Acid-Induced Cough in Congenitally Bronchial-Hypersensitive(BHS) and Bronchial-Hyposensitive (BHR) Guinea Pigs
- Airway Responsiveness to Acetylcholine in Congenitally Bronchial-Hypersensitive (BHS) and Bronchial-Hyposensitive (BHR) Guinea Pigs in Vivo and in Vitro
- Histamine-Induced Airway Contraction in Congenitally Bronchial-Hypersensitive (BHS) and Bronchial-Hyposensitive (BHR) Guinea Pigs
- Reduced Coronary Vasodilation in Patients With Familial Hypercholesterolemia Following Intracoronary Injection of Isosorbide Dinitrate
- c-Fos suppresses systemic inflammatory response to endotoxin
- Antihypertensive Effects of Peptides in Autolysate of Bonito Bowels on Spontaneously Hypertensive Rats
- The Daily Pattern of Cardiovascular Parameters in Kurosawa and Kusanagi-Hypercholesterolemic (KHC) Rabbits
- Diurnal Variation of Heart Rate, Locomotor Activity, and Body Temperature in Interleukin-1α/β Doubly Deficient Mice
- Power Spectral Analysis of Heart Rate Variability for Assessment of Diurnal Variation of Autonomic Nervous Activity in Guinea Pigs
- The Daily Pattern of Heart Rate, Body Temperature, and Locomotor Activity in Guinea Pigs
- The Daily Pattern of Heart Rate, Body Temperature, Locomotor Activity, and Autonomic Nervous Activity in Congenitally Bronchial-Hypersensitive (BHS) and Bronchial-Hyposensitive (BHR) Guinea Pigs
- Influence of Training on Heart Rate Variability in Young Thoroughbred Horses
- Effect of Acetylcholinesterase Activity on Pathogenesis of Airway Hyperresponsiveness in Guinea Pigs
- Effect of M_2 and M_3 Muscarinic Receptors on Airway Responsiveness to Carbachol in Bronchial-Hypersensitive (BHS) and Bronchial-Hyposensitive (BHR) Guinea Pigs
- 日本最高齢馬シンザンの心電図
- Effects of Insulin-Sensitizing Agent on Autonomic Nervous Function in Zucker-Fatty Rats(Nervous system, Proceedings of the 32nd Annual Meeting)
- Characteristics of Autonomic Nervous Function in Zucker-Fatty Rats : Investigation by Power Spectral Analysis of Heart Rate Variability
- Effects of Pair Housing on Diurnal Rhythms of Heart Rate and Heart Rate Variability in Miniature Swine
- Changes in Autonomic Control of Heart Associated with Classical Appetitive Conditioning in Rats
- Effects of Psychological Stress on Autonomic Control of Heart in Rats
- Charastalistics of delayed rectiire K^+ current in in vivo model of rabbi heart(Proceedings of the 32nd Annual Meeting)
- Morphological Variations in Trnasplanted Tumors Developed by Inoculation of Spontaneous Mesothelioma Cell Lines Derived from F344 Rats
- Universal External Carotid Artery to Proximal Middle Cerebral Artery Bypass With Interposed Radial Artery Graft Prior to Approaching Ruptured Blood Blister-Like Aneurysm of the Internal Carotid Artery : Technical Note
- The Influence of Chronic Sympathectomy on Cutaneous Blood Flow in the Rat Tail
- Heart Rates and Blood Lactate Response in Thoroughbred Horses during a Race
- Progesterone Concentration throughout Gestation in Cows with Singleton and Twin Pregnancies
- Optical imaging of respiratory burst activity in newborn rat medullary block preparations
- Comparative Study of Anti-Oncogenic MicroRNA-145 in Canine and Human Malignant Melanoma
- Arrhythmias and alterations in autonomic nervous function induced by deoxynivalenol (DON) in unrestrained rats
- REFLEX CONTROL OF GASTRIC MOTILITY BY THE VAGAL AND GREAT SPLANCHNIC NERVES IN THE DOG
- Arrhythmias and alterations in autonomic nervous function induced by deoxynivalenol (DON) in unrestrained rats
- Enhanced gastric retention of solid resin beads as a marker for emetic potential of agents in rats
- Augmented Activity of the Pelvic Nerve Afferent Mediated by TRP Channels in Dextran Sulfate Sodium (DSS)-Induced Colitis of Rats
- A Retrospective Study of Inflammatory Colorectal Polyps in Miniature Dachshunds
- Lyophilized Aspirin with Trehalose May Decrease the Incidence of Gastric Injuries in Healthy Dogs
- Dermal Cell Damage Induced by Topical Application of Non-Steroidal Anti-Inflammatory Drugs Is Suppressed by Trehalose Co-Lyophilization in Ex Vivo Analysis
- Loss- and gain-of-function analyses of vacuolar protein sorting 2 in Notch signaling of Drosophila melanogaster
- The Posterior Nasal Nerve Plays an Important Role on Cardiopulmonary Reflexes to Nasal Application of Capsaicin, Distilled Water and l-Menthol in Anesthetized Dogs.
- The Effect of Subacute Supplementation of Taurine on Spatial Learning and Memory
- Respiratory and Cardiovascular Reflexes Elicited by Nasal Instillation of Capsaicin to Anesthetized, Spontaneously Breathing Dogs.
- Effects of Perineural Capsaicin Treatment on Compound Action Potentials of Superior Laryngeal Nerve Afferents in Sevoflurane-Anesthetized Dogs.
- Cytotoxicity Induced by Recombinant Human Tumor Necrosis Factor-.ALPHA. Dependent on the Types of Its Receptors on Canine Cells.
- Nasal Sensory Receptors Responding to Capsaicin, Water and Tactile Stimuli in Sevoflurane-Anesthetized Dogs.
- Toxic effects of T-2 toxin and deoxynivalenol on the mitochondrial electron transport system of cardiomyocytes in rats
- Loss- and gain-of-function analyses of vacuolar protein sorting 2 in Notch signaling of Drosophila melanogaster